Measuring the response of human head and neck squamous cell carcinoma to irradiation in a microfluidic model allowing customized therapy [PDF]
, 2017 Radiotherapy is the standard treatment for head and neck squamous cell carcinoma (HNSCC), however, radioresistance remains a major clinical problem despite significant improvements in treatment protocols. Therapeutic outcome could potentially be improved
Beavis, Andrew W. +5 more
core +1 more source
Catalytic activity of the caspase-8-FLIPL complex inhibits RIPK3-dependent necrosis
Nature, 2011 Caspase-8 has two opposing biological functions—it promotes cell death by triggering the extrinsic pathway of apoptosis, but also has a survival activity, as it is required for embryonic development, T-lymphocyte activation, and resistance to necrosis ...
A. Oberst +8 more
semanticscholar +1 more source
Türkiye'deki soroptimistler boş durmuyor [PDF]
, 1964 Taha Toros Arşivi, Dosya No: 13-Berat Zeki-Zeki-Ekrem Zeki-Vedat Üngör.
Yeşim, Nazan
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Güneş klübünün taşlanması hadisesi:Fedarasyon hakemin tecziyesine karar verdi [PDF]
, 1935 Taha Toros Arşivi, Dosya Adı: Galatasarayİstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN ...
core
Slow plasmon modes in polymeric salt solutions
, 2000 The dynamics of polymeric salt solutions are presented. The salt consists of chains $\rm A$ and $\rm B$, which are chemically different and interact with a Flory-interaction parameter $\chi$, the $\rm A$ chain ends carry a positive charge whereas the ...
A Johner +5 more
core +1 more source
Caspase-8 Inactivation in T Cells Increases Necroptosis and Suppresses Autoimmunity in \(Bim^{−/−}\) Mice [PDF]
, 2013 Dysregulation of either the extrinsic or intrinsic apoptotic pathway can lead to various diseases including immune disorders and cancer. In addition to its role in the extrinsic apoptotic pathway, caspase-8 plays nonapoptotic functions and is essential ...
Bohgaki, Miyuki +8 more
core +1 more source
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
Nature, 2011 Apoptosis and necroptosis are complementary pathways controlled by common signalling adaptors, kinases and proteases; among these, caspase-8 (Casp8) is critical for death receptor-induced apoptosis.
W. Kaiser +7 more
semanticscholar +1 more source
BURSA İLİNDEKİ FAAL FUTBOL HAKEMLERİNİN PROBLEM ÇÖZME VE ATILGANLIK DÜZEYLERİNİN BELİRLENMESİ
Spormetre Beden Eğitimi ve Spor Bilimleri Dergisi, 2008 Bu çalışmada Bursa ilinde bulunan faal futbol hakemlerinin problem çözme ve atılganlık seviyeleri tespit edilmiştir. Bursa ilinde faal olan 91 erkek futbol hakemi incelenmiştir. Hakemler farklı klasmanlardadır.
Mehmet Efe +2 more
doaj +1 more source
Apaf1 is required for mitochondrial pathways of apoptosis and brain development.
Cell, 1998 Apoptosis is essential for the precise regulation of cellular homeostasis and development. The role in vivo of Apaf1, a mammalian homolog of C. elegans CED-4, was investigated in gene-targeted Apaf1-/- mice.
Hiroki Yoshida +15 more
semanticscholar +1 more source