Results 51 to 60 of about 1,593,354 (203)

Mechanical Signatures of Nucleic Acid Trefoil Knot Topology

Angewandte Chemie, EarlyView.
Single‐stranded DNA can be designed with sequences that self‐thread into topological knots. The exact same sequence can alternatively be turned into an unknotted pseudoknot. The topology of the resulting polymer is determined by applying force with optical tweezers, causing the pseudoknot to resolve but the knot to tighten.
David t.R. Bakker, Micah Yang, Isaac T. S. Li   +2 more
wiley   +2 more sources

Hardware Impaired Self-Energized Bidirectional Sensor Networks over Complex Fading Channels

Sensors, 2020
Rapid emergence of wireless sensor networks (WSN) faces significant challenges due to limited battery life capacity of composing sensor nodes. It is substantial to construct efficient techniques to prolong the battery life of the connected sensors in ...
Stefan R. Panic, Dushantha Nalin K. Jayakody, Sofiene Affes, Palanivelu Muthuchidambaranathan   +3 more
doaj   +1 more source

Advances in Aptamer Drug Delivery Systems for Treatment of Glioblastoma

Advanced Science, EarlyView.
Aptamers have remarkable recognition capacity which is suitable for assisting drug delivery for GB. This review demonstrates that aptamers have great potential as targeted therapeutic carriers, conjugated to various therapeutic carriers, using a range of conjugation strategies and chemistries.
Alexandra R. Paul, Alexandra Moreno Mitchell, Dean O'Neil, Yutong Luo, Khuloud T. Al‐Jamal   +4 more
wiley   +1 more source

RNA Organelles in DNA‐Based Artificial Cells Provide Spatial Aptamer Functions and Enhanced Signal Processing

Angewandte Chemie, EarlyView.
Multiphase DNA–RNA artificial cells integrate a protective DNA shell, a transcriptionally active DNA core, and a functional RNA organelle. Spatial compartmentalization enables signal generation, external protein expression, and selective recapture via RNA aptamers. ABSTRACT Naturally occurring biomolecular condensates orchestrate key cellular processes
Maria Vonk‐de Roy, Daniel Hoenders, Laia Civit, Julián Valero, Andreas Walther   +4 more
wiley   +2 more sources

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

Advanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu, Yingyu Zhang, Xianwei Zhang, Mengxin Zhang, Fei Zhang, Jushan Sun, Yahui Yang, Kangbo Liu, Peng Wang, Shuying Luo, Wancun Zhang   +10 more
wiley   +1 more source

The Cytoplasmic MicroRNA‐Production Complex Regulates MicroRNA Sorting to Extracellular Vesicles During Synaptogenesis

Advanced Science, EarlyView.
The mechanisms of microRNA cargo sorting to extracellular vesicles, important mediators of cell communication, are not fully understood. This study reveals that the microRNA‐production machinery acts as a ‘hub’ for the sorting of microRNAs to extracellular vesicles, a process regulated by dynamic organelle interactions.
Yuzhou Zeng, Selina Luhmann, Aditi Saha, Marta Orlando, Haider Sami, Timo Glatter, Anna Antoniou   +6 more
wiley   +1 more source

Static and dynamic power splitting protocol enabled in DF energy harvesting Half-Duplex relaying network: Ergodic capacity analysis

CTU Journal of Innovation and Sustainable Development
In this research, we propose and examine the DF Energy Harvesting Half-Duplex Relaying Network. For this system model, the DF Energy Harvesting Half-Duplex Relaying Network is analyzed in two cases: Static and Dynamic Power Splitting Protocol.
Nhat Tan Nguyen, Nhat Tien Nguyen
doaj   +3 more sources

Performance Analysis of RIS-Assisted Bi-Directional Full-Duplex Systems Under Hardware Impairments and Nakagami-m Fading Channels

Journal of Communications Software and Systems
This paper investigates the performance of reflec tive intelligent surface (RIS)-assisted bi-directional full-duplex (FD) systems considering hardware impairments (HIs), and self interference (SI) under Nakagami-m fading.
Rajesh Ramanathan, Bagubali Annasamy
doaj   +1 more source

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

Advanced Science, EarlyView.
A low‐density lipoprotein receptor‐oriented biomimetic nanoplatform couples brain‐tumor delivery with a mechanistically matched regorafenib‐erythrodiol combination. Concurrent disruption of autophagic nutrient salvage and cholesterol homeostasis collapses bioenergetic and signaling support, suppresses glioblastoma stemness, and promotes immunogenic ...
Yining Jiang, Wenzhuo Yang, Wenting Cheng, Jing Zuo, Lin Pan, Sheng Zhong, Ren Geng, Yao Zhao, Zijian Chen, Canhua Huang, Yang Bai, Liyan Zhao, Yunqian Li   +12 more
wiley   +1 more source

Full Duplex AF and DF Relaying Under Channel Estimation Errors for V2V Communications

IEEE Access, 2018
In this paper, we investigate the outage performance of full-duplex (FD) and half-duplex (HD) vehicle to vehicle (V2V) networks. We consider two vehicular communication scenarios with the assistance of roadside unit (RSU), i.e., RSU-to-vehicle-to-vehicle
Siye Wang, Dandi Wang, Chao Li, Wenbo Xu
doaj   +1 more source