Results 81 to 90 of about 1,593,354 (203)

A Cytosine‑Bulged (3+1) Hybrid G‑Quadruplex Formed by the Chicken DNA Replication Origin

open access: yesChemistry – A European Journal, EarlyView.
The first high‐resolution structure of an OGRE‐derived G‐quadruplex from the chicken β‐globin replication origin reveals an intramolecular three‐layer (3+1) hybrid fold with a cytosine bulge and an unprecedented 5'‐outer‐quartet anti guanine, creating a distinctive surface for molecular recognition.
Yingying You   +13 more
wiley   +1 more source

A Survey of Delay-Oriented Dynamic Link Scheduling Policies for 5G/6G Integrated Access and Backhaul Systems

open access: yesIEEE Access
Integrated Access and Backhaul (IAB) is expected to become a key part of the 5G and future cellular systems enabling cost-controlled network densification.
Anna Zhivtsova   +3 more
doaj   +1 more source

Introduction of a Double‐Headed Nucleotide Into G‐Quadruplex DNA: Position‐Dependent Stabilization and Structural Insights

open access: yesChemistry – A European Journal, EarlyView.
A double‐headed bis‐guanine (G) nucleotide (GG) was evaluated as a noncanonical building block in G‐quadruplexes (G4s). Biophysical and computational analyses reveal that GG can directly participate in G‐tetrads and strongly stabilize G4s in a position‐ and topology‐dependent manner. These findings establish design rules for using GG to engineer highly
Krista Urup   +5 more
wiley   +1 more source

Queueing and channel access delay analysis in in-band full-duplex wireless networks

open access: yesInternational Journal of Distributed Sensor Networks, 2019
In-band full-duplex wireless communication, which supports a node to transmit and receive simultaneously in the same frequency band, is receiving growing interest.
Yanjing Sun   +3 more
doaj   +1 more source

4′‐ThioRNA Substitution and Sense‐Strand Segmentation for the Design of Functional Fully Modified siRNAs Targeting SARS‐CoV‐2

open access: yesChemistry – A European Journal, EarlyView.
4′‐ThioRNA was broadly tolerated across multiple positions in SARS‐CoV‐2‐targeting siRNAs, but full 4'‐thio modification of both strands caused a reduction in RNAi activity. Sense‐strand segmentation improved RNAi and antiviral activity, particularly when the nick was located at position 10 from the 5′‐end of the sense strand, thereby unlocking the ...
Yuhei Nogi   +5 more
wiley   +1 more source

Deciphering transcriptome complexity via long‐read sequencing

open access: yesiMeta, EarlyView.
Long‐read sequencing is transforming transcriptomics from gene‐level quantification to isoform‐resolved interpretation by directly resolving full‐length transcript structures, transcription in repetitive regions, and linked molecular features. This review provides an end‐to‐end roadmap covering sequencing platforms, library preparation strategies ...
Chuwen Xu   +21 more
wiley   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

open access: yesInterdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li   +7 more
wiley   +1 more source

Subzero tensile properties of a welded duplex stainless steel [PDF]

open access: yes, 2012
Nel presente lavoro vengono studiate propriet tensili di diversi tipi di saldatura su acciaio duplex LDX2101. Questo acciaio destinato a generici usi industriali, qualora particolari propriet meccaniche, corrosive ed economicità vengano richieste ...
Casarotto, Paolo
core  

Intrinsically Design‐Rule‐Compliant Nanophotonic Inverse Design via Learned Generative Manifolds

open access: yesLaser &Photonics Reviews, EarlyView.
A generative reparameterization framework for nanophotonic inverse design is introduced, restricting optimization to a learned manifold of design‐rule‐compliant geometries. Unlike conventional penalty‐based approaches, fabrication constraints are encoded intrinsically within the design representation.
Bahrem Serhat Danis   +8 more
wiley   +1 more source

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