Results 101 to 110 of about 1,925,041 (282)

The Cyclic Antimicrobial Peptide C-LR18 Has Enhanced Antibacterial Activity, Improved Stability, and a Longer Half-Life Compared to the Original Peptide

Antibiotics
Background: LR18 is an α₋helical AMP with high antimicrobial activity, low hemolytic activity, and low cytotoxicity. However, the susceptibility to degradation of the peptidase enzyme and a short half-life hinder its application as a therapeutic agent ...
Zhihua Pei, Qiaoxi Song, Jingqi Xu, Shuang Yu, Hongxia Ma   +4 more
doaj   +1 more source

Is There Any Regional Price Disparity in Peninsular Malaysia? [PDF]

Romanian Review of Regional Studies, 2015
This study examines whether there are significant differences in prices across four regions in Peninsular Malaysia, namely Northern, Central, Southern, and Eastern Peninsular Malaysia. Disaggregate monthly consumer price indices for twelve types of goods
LEE CHIN
doaj  

Human FcRn Tissue Expression Profile and Half-Life in PBMCs

Biomolecules, 2019
System-wide quantitative characterization of human neonatal Fc receptor (FcRn) properties is critical for understanding and predicting human PK (pharmacokinetics) as well as the distribution of mAbs and Fc-fusion proteins using PBPK (physiologically ...
Yao-Yun Fan, Vahid Farrokhi, Teresa Caiazzo, Mengmeng Wang, Denise M. O’Hara, Hendrik Neubert   +5 more
doaj   +1 more source

Quantifying the half-life of deviations from PPP: The role of economic priors [PDF]

The half-life of deviations from purchasing power parity (PPP) plays a central role in the ongoing debate about the ability of macroeconomic models to account for the time series behavior of the real exchange rate.
Lutz Kilian, Tao Zha
core  

Precision half-life measurement of the 4-fold forbidden electron capture of V-50

, 2011
A sensitive search of the 4-fold forbidden non-unique beta decay of V-50 has been performed. A total exposure of 185.8 kg x d has been accumulated. A reliable half-life value with the highest precision so far of $(2.29 \pm 0.25) \cdot 10^{17}$ years of ...
Dombrowski, H., Neumaier, S., Zuber, K.
core   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Measurement of double beta decay of 100Mo to excited states in the NEMO 3 experiment

, 2006
The double beta decay of 100Mo to the 0^+_1 and 2^+_1 excited states of 100Ru is studied using the NEMO 3 data. After the analysis of 8024 h of data the half-life for the two-neutrino double beta decay of 100Mo to the excited 0^+_1 state is measured to ...
A. Nachab, A. Smolnikov, A.I. Etienvre, A.J. Caffrey, A.S. Barabash, Abad, Ahmad, Ahmad, Ahmed, Altman, Arnold, Arnold, Arnold, Arnold, Aunola, Bahcall, Barabash, Barabash, Barabash, Barabash, Barabash, Barabash, Barabash, Berger, Bilenky, Blum, Busto, C. Augier, C. Jollet, C. Longuemare, C.S. Sutton, Ch. Marquet, Civitarese, Cleveland, D. Lalanne, Dassié, Dassié, De Braeckeleer, de Holanda, Doi, Domin, Eguchi, Ejiri, Elliot, F. Hubert, F. Leccia, F. Mauger, F. Perrot, F. Piquemal, F. Šimkovic, Faessler, Fukuda, Fukuda, G. Broudin, G. Lutter, G. Szklarz, Garcia, Gavrin, Griffiths, H. Ohsumi, Hirsch, I. Vanyushin, I. Štekl, J. Baker, J. Jerie, J. Suhonen, J. Thomas, J.L. Reyss, J.S. Ricol, Junk, Kisel, Kudomi, L. Simard, L. Vála, M. Bongrand, Maltoni, N. Fatemi-Ghomi, O. Kochetov, Pascoli, Pascoli, Pascoli, Ph. Hubert, R. Arnold, R. Saakyan, Rodin, S. Jullian, S. King, S. Söldner-Rembold, S.I. Konovalov, Schwieger, Sobel, Stoica, Suhonen, Suhonen, Suhonen, T. Lamhamdi, Tomoda, Tomoda, Ts. Vylov, V. Brudanin, V. Egorov, V. Kovalenko, V. Timkin, V. Tretyak, V. Umatov, V. Vasiliev, V. Vorobel, Vergados, X. Sarazin, Y. Lemière, Yu. Shitov, Šimkovic, Šimkovic   +112 more
core   +2 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source