Results 91 to 100 of about 1,925,041 (282)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

The retinoblastoma protein contributes to maintaining the stability of HPV E7 in cervical cancer cells

Journal of Virology
High-risk human papillomaviruses (HR HPV)-16 and -18, and other closely related subtypes, are associated with at least 90% of human cervical cancers.
Ifeoluwa Gbala, Nezka Kavcic, Lawrence Banks   +2 more
doaj   +1 more source

Feasibility study of the observation of the neutrino accompanied double beta-decay of Ge-76 to the 0+(1) excited state of Se-76 using segmented germanium detectors [PDF]

, 2007
Neutrino accompanied double beta-decay of Ge-76 can populate the ground state and the excited states of Se-76. While the decay to the ground state has been observed with a half-life of 1.74 +0.18 -0.16 10^21 years, decays to the excited states have not ...
Kroeninger, K., Pandola, L., Tretyak, V.
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

The role of N-terminal phosphorylation of DGK-θ

Journal of Lipid Research
Diacylglycerol kinases (DGKs) are lipid kinases that mediate the phosphorylation of diacylglycerol (DAG) leading to the production of phosphatidic acid (PtdOH). To examine the role of phosphorylation on DGK-θ, we first identified the phosphorylated sites
Millie X. Barbernitz, Lauren R. Devine, Robert N. Cole, Daniel M. Raben   +3 more
doaj   +1 more source

Determination of the energy transitions and half-lives of Rubidium nuclei

Open Physics, 2018
The photonuclear reactions, first extensively studied in the 1970’s and performed using the gamma rays obtained via bremsstrahlung, are a standard nuclear physics experiment.
Biçer Ahmet, Manisa Kaan, Engin Çalık Abdullah, Erdoğan Mehmet, Şen Mürsel, Bircan Hasan, Dapo Haris, Boztosun Ismail   +7 more
doaj   +1 more source

Measurement of double beta decay of ¹⁰⁰Mo to excited states in the NEMO 3 experiment [PDF]

, 2007
The double beta decay of ¹⁰⁰Mo to the 0_{1}^{+} and 2_{1}^{+} excited states of ¹⁰⁰Ru is studied using the NEMO 3 data. After the analysis of 8024 h of data the half-life for the two-neutrino double beta decay of ¹⁰⁰Mo to the excited 0_{1}^{+} state is ...
Arnold, R, Augier, C, Baker, J, Barabash, AS, Bongrand, M, Broudin, G, Brudanin, V, Caffrey, AJ, Egorov, V, Etienvre, AI, Fatemi-Ghomi, N, Hubert, F, Hubert, P, Jerie, J, Jollet, C, Jullian, S, King, S, Kochetov, O, Konovalov, SI, Kovalenko, V, Lalanne, D, Lamhamdi, T, Leccia, F, Lemière, Y, Longuemare, C, Lutter, G, Marquet, C, Mauger, F, Nachab, A, Ohsumi, H, Perrot, F, Piquemal, F, Reyss, JL, Ricol, JS, Saakyan, R, Sarazin, X, Shitov, Y, Simard, L, Smolnikov, A, Suhonen, J, Sutton, CS, Szklarz, G, Söldner-Rembold, S, Thomas, J, Timkin, V, Tretyak, V, Umatov, V, Vanyushin, I, Vasiliev, V, Vorobel, V, Vylov, T, Vála, L, Šimkovic, F, Štekl, I   +53 more
core  

High precision half-life measurement of $^{147}$Sm $\alpha$ decay from thin-film sources

, 2017
An investigation of the {\alpha}-decay of $^{147}$Sm was performed using an ultra low-background Twin Frisch-Grid Ionisation Chamber (TF-GIC). Four natural samarium samples were produced using pulsed laser deposition in ultra high vacuum.
Degering, Detlev, Heller, René, Neu, Volker, Wilsenach, Heinrich, Zuber, Kai   +4 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Relationship between the timing of relapse and plasma drug levels following discontinuation of cariprazine treatment in patients with schizophrenia: indirect comparison with other second-generation antipsychotics after treatment discontinuation

Neuropsychiatric Disease and Treatment, 2019
Christoph U Correll,1–3 Rakesh Jain,4 Jonathan M Meyer,5 Antonia Periclou,6 Timothy Carrothers,6 Ágota Barabássy,7 Mehul Patel,8 Willie Earley91Department of Psychiatry, Northwell Health, The Zucker Hillside Hospital, Glen Oaks, NY ...
Correll CU, Jain R, Meyer JM, Periclou A, Carrothers T, Barabássy Á, Patel M, Earley W   +7 more
doaj