Results 91 to 100 of about 6,618,367 (274)

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Existence of non-oscillatory solutions for second-order advanced half-linear differential equations

Electronic Journal of Differential Equations, 2013
In this article, we establish the necessary and sufficient conditions for existence of non-oscillatory solutions for the second-order advanced half-linear differential equation $$ ig(r(t)|x'(t)|^{alpha-1}x'(t)ig)'+p(t)|x(h(t)ig)|^{alpha-1}x(h(t))=0,
Aijun Cheng, Zhiting Xu
doaj  

Oscillatory behavior of the second order noncanonical differential equations

Electronic Journal of Qualitative Theory of Differential Equations, 2019
Establishing monotonical properties of nonoscillatory solutions we introduce new oscillatory criteria for the second order noncanonical differential equation with delay/advanced argument \begin{equation*} (r(t)y'(t))'+p(t)y(\tau(t))=0. \end{equation*}
Blanka Baculíková
doaj   +1 more source

On the oscillation of higher-order half-linear delay differential equations

Applied Mathematics Letters, 2011
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Chenghui Zhang, Tongxing Li, Bo Sun, Ethiraju Thandapani   +3 more
openaire   +2 more sources

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Generalized Prüfer angle and oscillation of half-linear differential equations

Applied Mathematics Letters, 2017
The Euler half-linear differential equation \[ \left[t^{\alpha-1}\,\Phi(x')\right]'+\gamma\,t^{\alpha-p-1}\,\Phi(x)=0\,,\quad \alpha\neq p \] is a typical example of the so-called \textit{conditionally oscillatory} half-linear differential equation. It is oscillatory if \(\gamma\,p^p> |p-\alpha|^p\) and non-oscillatory in the opposite case, that is, \(\
Ondrej Doslý, Jaroslav Jaros, Michal Veselý   +2 more
openaire   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source

Small solutions of the damped half-linear oscillator with step function coefficients

Electronic Journal of Qualitative Theory of Differential Equations, 2016
In this paper we consider the damped half-linear oscillator \begin{equation*} x''|x'|^{n-1} + c(t) |x'|^{n-1} x' + a(t)|x|^{n-1}x=0, \qquad n \in \mathbb{R}^+. \end{equation*} We give a sufficient condition guaranteeing the existence of a small solution,
Attila Dénes, László Székely
doaj   +1 more source