Results 71 to 80 of about 612,872 (266)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Asymptotic formulas for solutions of half-linear Euler-Weber equation

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2008
We establish improved asymptotic formulas for nonoscillatory solutions of the half-linear Euler-Weber type differential equation $$ (\Phi(x'))'+\left[\frac{\gamma_p}{t^p}+\frac{\mu_p}{t^p\log^2 t}\right]\Phi(x)=0, \quad \Phi(x):=|x|^{p-2}x,\quad p>1 ...
Zuzana Pátíková
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Secants of Abelian Varieties, Theta functions, and Soliton Equations

open access: yes, 1996
This paper is a survey on relations between secant identities and soliton equations and applications of soliton equations to problems of algebraic geometry, i.e., the Riemann-Schottky problem and its analogues.
Taimanov, I. A.
core   +2 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Oscillation results for second-order half-linear differential equations

open access: yesMathematical and Computer Modelling, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Sturm-Liouville Eigenvalue Problems for Half- Linear Ordinary Differential Equations

open access: yesRocky Mountain Journal of Mathematics, 2001
The authors consider the half-linear Sturm-Liouville eigenvalue problem \[ \begin{gathered} (p(t)|x'|^{\alpha-1}x')'+\lambda q(t)|x|^{\alpha-1}x=0, \qquad a\leq t\leq b,\tag{HL}\\ Ax(a)-A'x'(a)=0,\qquad Bx(b)+B'x'(b)=0,\end{gathered} \] where \(\alpha>0\) is a constant, \(p,q\) are real-valued continuous functions on \([a,b]\) with \(p(t)>0\) and ...
Kusano, Takaŝi, Naito, Manabu
openaire   +4 more sources

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Forced Oscillation of Second-Order Half-Linear Dynamic Equations on Time Scales

open access: yesAbstract and Applied Analysis, 2010
We will establish a new interval oscillation criterion for second-order half-linear dynamic equation (r(t)[xΔ(t)]α)Δ+p(t)xα(σ(t))=f(t) on a time scale T which is unbounded, which is a extension of the oscillation result for second order linear dynamic ...
Quanwen Lin, Baoguo Jia, Qiru Wang
doaj   +1 more source

Home - About - Disclaimer - Privacy