Results 61 to 70 of about 58,243 (254)

Oscillatory Behavior of Even-Order Half-Linear Neutral Differential Equations

International Journal of Differential Equations, 2022
This paper discusses some sufficient conditions for oscillatory behavior of even-order half-linear neutral differential equation. An example is given to illustrate the main result.
S. Sangeetha, S. K. Thamilvanan, Ethiraju Thandapani   +2 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Forced Oscillation of Second-Order Half-Linear Dynamic Equations on Time Scales

Abstract and Applied Analysis, 2010
We will establish a new interval oscillation criterion for second-order half-linear dynamic equation (r(t)[xΔ(t)]α)Δ+p(t)xα(σ(t))=f(t) on a time scale T which is unbounded, which is a extension of the oscillation result for second order linear dynamic ...
Quanwen Lin, Baoguo Jia, Qiru Wang
doaj   +1 more source

On increasing solutions of half-linear delay differential equations

Mathematics for Application, 2020
submitted ...
Serena Matucci, Pavel Řehák
openaire   +5 more sources

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

The boundary value problem for an ordinary linear half-order differential equation

Қарағанды университетінің хабаршысы. Математика сериясы
This study is devoted to the study of the solution of a boundary value problem for an ordinary linear differential equation of half order with constant coefficients.
N. Aliyev, M. Rasulov, B. Sinsoysal
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Comparison theorems for even order half-linear differential equations

Applied Mathematics Letters, 2012
The author establishes some generalization of Picone's formula for half-linear differential operators and presents its application to comparison ...
openaire   +2 more sources

Generalized Prüfer angle and oscillation of half-linear differential equations

Applied Mathematics Letters, 2017
The Euler half-linear differential equation \[ \left[t^{\alpha-1}\,\Phi(x')\right]'+\gamma\,t^{\alpha-p-1}\,\Phi(x)=0\,,\quad \alpha\neq p \] is a typical example of the so-called \textit{conditionally oscillatory} half-linear differential equation. It is oscillatory if \(\gamma\,p^p> |p-\alpha|^p\) and non-oscillatory in the opposite case, that is, \(\
Ondrej Doslý, Jaroslav Jaros, Michal Veselý   +2 more
openaire   +1 more source