Results 51 to 60 of about 6,618,367 (274)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Conjugacy criteria for half-linear differential equations [PDF]
, 1999 summary:Sufficient conditions on the function $c(t)$ ensuring that the half-linear second order differential equation \[ (|u^\prime |^{p-2} u^\prime )^\prime + c(t)|u(t)|^{p-2} u(t)=0\,, \quad \quad p>1 \] possesses a nontrivial solution having at least ...
Peňa, Simón
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Hartman-type comparison theorems for half-linear differential equations of the second order
Electronic Journal of Qualitative Theory of Differential Equations, 2012 Comparison theorem of the Hartman type for a continuous family of nonlinear differential equations of the form $$ \big(p(t, \lambda)\varphi(u')\big)' + q(t,\lambda) \varphi(u) = 0, \lambda \geq 0, \quad \tag{ $\rm E_\lambda$}$$ where $ p \in \mathrm{C ...
Jaroslav Jaroš
doaj +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Forced oscillation of super-half-linear impulsive differential equations
Computers & Mathematics with Applications, 2007 The aim of this work is to establish new oscillation criteria for forced super-half-linear equations of the form \[ \begin{alignedat}{2} 2 (m(t)\varphi_\alpha(y'))'&+ q(t)\varphi_\beta(y)= f(t),&\quad t&\neq \theta_i,\\ \Delta(m(t)\varphi_\alpha(y'))&+ q_i\varphi_\beta(y)= f_i,&\quad t&= \theta_i,\;i\in\mathbb{N}, \end{alignedat} \] where \(\beta\geq ...
Abdullah Özbekler, Agacik Zafer
openaire +3 more sources
Neumann problem on the semi-line for the Burgers equation [PDF]
, 2011 In this article, the Neumann problem on the semi-line for the Burgers equation is considered. The problem is reduced to a nonlinear integral equation in one independent variable, whose unique solution is proven to exist for small time.
Sommacal, Matteo, de Lillo, Silvana
core +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Hille-Wintner type comparison kriteria for half-linear second order differential equations [PDF]
, 2006 summary:We establish Hille-Wintner type comparison criteria for the half-linear second order differential equation \[ \left(r(t)\Phi (x^{\prime })\right)^{\prime }+c(t)\Phi (x)=0,\quad \Phi (x)=|x|^{p-2}x\,,\ p>1\,, \] where this equation is viewed as a ...
Došlý, Ondřej, Pátíková, Zuzana
core +1 more source
A remark on the linearization technique in half-linear oscillation theory [PDF]
Opuscula Mathematica, 2006 We show that oscillatory properties of the half-linear second order differential equation \[(r(t)\Phi(x'))'+c(t)\Phi(x)=0,\qquad\Phi(x)=|x|^{p-2}x,\quad p\gt 1,\] can be investigated via oscillatory properties of a certain associated second order linear ...
Ondřej Došlý
doaj