Next‐Generation Manufacturing: The Evolving Role of Biocatalysis in AstraZeneca
Biocatalysis is strengthening AstraZeneca's manufacture of active pharmaceutical ingredients through faster development, robust scale‐up, and lower environmental impact. Case studies illustrate where biocatalysis delivers greatest value, while enabling platforms, teams, and partnerships shape its next phase.
Alba Diaz‐Rodriguez +4 more
wiley +1 more source
HALOGENATION: PART XXIII. HALOGENATION OF FLUOROBENZENE, o-, m-, AND p-FLUOROTOLUENES
Fluorobenzene, o-,m- and p-fluorotoluenes have been chlorinated, brominated and iodinated under different conditions as a result of which mixed halogen derivatives have been obtained by direct ...
K. S. VENKAT RAMAN +2 more
core +1 more source
Regioselective halogenation of lavanducyanin by a site-selective vanadium-dependent chloroperoxidase [PDF]
Halogenated phenazine meroterpenoids are a structurally unusual family of marine actinobacterial natural products that exhibit antibiotic, anti-biofilm, and cytotoxic bioactivities.
Shaun, McKinnie, Jackson, Baumgartner
core +2 more sources
Halogenation. Part X. Iodination of Xylenes and Mono-iodoxylenes.
Halogenation. Part X.
K. S. VENKAT RAMAN, PHULDEO SAHAY VARMA
core +1 more source
Azaporphyrinoid‐Based Photo‐ and Electroactive Architectures for Advanced Functional Materials
A long‐standing collaboration between the Torres and Guldi groups has yielded diverse azaporphyrinoid‐based donor‐acceptor nanohybrids with promising applications in solar energy conversion. This conspectus highlights key molecular platforms and structure‐function relationships that govern light and charge management, supporting the rational design of ...
Jorge Labella +3 more
wiley +1 more source
Intermolecular halogen...halogen contacts in crystals with heteroatomic halogens [PDF]
openaire +1 more source
From Sourcing to End‐of‐Life: Sustainability Challenges and Opportunities in Organic Bioelectronics
Organic bioelectronics bridges biology and electronics using organic mixed ionic/electronic conductors. This Perspective addresses sustainability across the full lifecycle of organic bioelectronic materials and devices, offering a framework to guide material sourcing, synthesis, fabrication, application, and end‐of‐life strategies toward bioelectronic ...
Gwennaël Dufil +3 more
wiley +1 more source
Sixteen indazole–sulfonamide hybrids exhibit species‐dependent antibacterial activity against E. coli and S. aureus, with the lead compound displaying an eightfold lower MIC than sulfathiazole against E. coli. Molecular docking against wild‐type and Sul1‐resistant dihydropteroate synthase identifies a candidate retaining binding affinity toward the ...
Romaisaa Boudza +8 more
wiley +1 more source
Heterocyclic‐Based Fungicides: Emerging Strategies for Viable Plant Disease Control
Heterocyclic compounds have attracted considerable attention because of their structural diversity, potent antifungal activity, and ability to interact with multiple fungal targets, offering broad‐spectrum protection against phytopathogens. Synthetic and semisynthetic/part‐natural scaffolds, particularly azole, quinoline, indole, cyclotryptamine, and ...
Sumit Tahlan +4 more
wiley +1 more source
Endophytic Fungi Natural Factories of Novel Bioactive Compounds
This review provides a systematic analysis of 242 natural products isolated from 42 genera of endophytic fungi, highlighting their remarkable structural diversity and broad spectrum of biological activities . ABSTRACT Endophytic fungi represent a prolific and chemically diverse source of novel specialized metabolites with significant pharmacological ...
Dilmurod Murodullayev +18 more
wiley +1 more source

