Results 81 to 90 of about 25,792 (269)
Synthesis and Characterization of Mixed Methyl/Allyl Monolayers on Si(111) [PDF]
, 2010 The formation of mixed methyl/allyl monolayers has been accomplished through a two-step halogenation/alkylation reaction on Si(111) surfaces. The total coverage of alkylated Si, the surface recombination velocities, and the degree of surface oxidation as
Brunschwig, Bruce S. +3 more
core +1 more source
Deploying Microbial Synthesis for Halogenating and Diversifying Medicinal Alkaloid Scaffolds
Frontiers in Bioengineering and Biotechnology, 2020 Plants produce some of the most potent therapeutics and have been used for thousands of years to treat human diseases. Today, many medicinal natural products are still extracted from source plants at scale as their complexity precludes total synthesis ...
Samuel A. Bradley +2 more
doaj +1 more source
Serum protein halogenation and nitrosylation: trait of maintained overstimulation of blood phagocytes in sporadic Parkinson’s disease [PDF]
, 2013 Introduction: Halogenative and nitrosative stress are two types of oxidative stress that have been proposed as pathogenic mechanisms in Parkinson’s disease (PD). They can be caused by overstimulation of phagocytes. This hypothesis discusses serum protein
Fernández-Espejo, Emilio
core +1 more source
Transmission Infrared Spectra of CH_3-, CD_3-, and C_(10)H_(21)-Ge(111) Surfaces [PDF]
, 2011 The surface chemistry of CH_3–, CD_3–, and C_(10)H_(21)–Ge(111) surfaces prepared through a bromination/alkylation method have been investigated by infrared spectroscopy. Well-ordered CH_3–Ge(111) surfaces could be prepared only if, prior to bromination,
Brunschwig, Bruce S. +2 more
core +1 more source
Structural Insights from Molecular Dynamics Simulations of Tryptophan 7-Halogenase and Tryptophan 5-Halogenase [PDF]
, 2018 Many natural organic compounds with pharmaceutical applications, including antibiotics (chlortetracycline and vancomycin), antifungal compounds (pyrrolnitrin), and chemotherapeutics (salinosporamide A and rebeccamycin) are chlorinated.
Ainsley, Jon +5 more
core +7 more sources
ChemistryEurope, EarlyView.A modular synthetic approach enables the preparation of azulene‐fused heterocycles via nucleophilic aromatic substitution followed by intramolecular cyclization of alkynyl fluoroazulenes. The method allows the incorporation of various heteroatoms (N, O, S, Se, and Te), leading to structurally diverse heteroannulated azulenes.
Martin C. Dietl +8 more
wiley +1 more source
Heterochirality and Halogenation Control Phe-Phe Hierarchical Assembly [PDF]
, 2020 Slavko Kralj +11 more
openalex +1 more source
ChemistryEurope, EarlyView.Following the Danube Flow. The first total syntheses of highly brominated rubrolides T, U, and U‐analog, together with the efficient and divergent syntheses of rubrolides A, D, and P. The dibrominated key intermediate, obtained via a Suzuki‐Miyaura cross‐coupling reaction, is the centerpiece of the synthesis.
Jasmin Janneschütz +7 more
wiley +1 more source
ChemistryOpen, 2020 Screening for an interesting biocatalyst and its subsequent kinetic characterization depends on a reliable activity assay. In this work, a fluorometric assay based on the halogenation of 4‐methyl‐7‐diethylamino‐coumarin was established to monitor ...
Alexander V. Fejzagić +5 more
doaj +1 more source
Catalytic electrophilic halogenation of silyl-protected and terminal alkynes: trapping gold(I) acetylides vs. a bronsted acid-promoted reaction [PDF]
, 2012 In the presence of a cationic gold(I) catalyst and N-halosuccinimide, both trimethylsilyl-protected and terminal alkynes are converted into alkynyl halides.
D'Oyley, JM +3 more
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