Results 181 to 190 of about 8,618 (217)

Engineering Halomonas bluephagenesis for L-Threonine production

Metabolic Engineering, 2020
Halophilic Halomonas bluephagenesis (H. bluephagenesis), a chassis for cost-effective Next Generation Industrial Biotechnology (NGIB), was for the first time engineered to successfully produce L-threonine, one of the aspartic family amino acids (AFAAs).
Du, Hetong, Zhao, Yiqing, Wu, Fuqing, Ouyang, Peifei, Chen, Jinchun, Jiang, Xiaoran, Ye, Jianwen, Chen, Guo-Qiang   +7 more
openaire   +2 more sources

Polyhydroxyalkanoates (PHA) from Halomonas pacifica ASL10 and Halomonas salifodiane ASL11 isolated from Mariout salt lakes

International Journal of Biological Macromolecules, 2020
Two novel PHA producing bacterial strains were chosen out of 12 strains collected from Mariout salt lakes. Analysis of 16srRNA gene sequence of the two new strains revealed 95.38% and 98.78% similarity to that of Halomonas pacifica and Halomonas salifodiane, respectively.
Fady Abd, El-Malek, Aida, Farag, Sanaa, Omar, Heba, Khairy   +3 more
openaire   +2 more sources

Halomonas borealis sp. nov. and Halomonas niordiana sp. nov., two new species isolated from seawater

Systematic and Applied Microbiology, 2020
Two Gram-negative strains obtained from tank water in a scallop hatchery in Norway, were phenotypically and genotypically characterized in order to clarify their taxonomic position. On the basis of 16S rRNA gene sequence analysis, these isolates, ATF 5.2T and ATF 5.4T, were included in the genus Halomonas, being their closest relatives H.
Ana L, Diéguez, Sabela, Balboa, Jesús L, Romalde   +2 more
openaire   +2 more sources

Ectoine hyperproduction by engineered Halomonas bluephagenesis

Metabolic Engineering
Ectoine, a crucial osmoprotectant for salt adaptation in halophiles, has gained growing interest in cosmetics and medical industries. However, its production remains challenged by stringent fermentation process in model microorganisms and low production level in its native producers.
Qitiao Hu, Simian Sun, Zhongnan Zhang, Wei Liu, Xueqing Yi, Hongtao He, Nigel S. Scrutton, Guo-Qiang Chen   +7 more
openaire   +2 more sources

Engineering Halomonas bluephagenesis via small regulatory RNAs

Metabolic Engineering, 2022
Halomonas bluephagenesis, a robust and contamination-resistant microorganism has been developed as a chassis for "Next Generation Industrial Biotechnology". The non-model H. bluephagenesis requires efficient tools to fine-tune its metabolic fluxes for enhanced production phenotypes.
Li-Juan Wang, Xiao-Ran Jiang, Jie Hou, Cong-Han Wang, Guo-Qiang Chen   +4 more
openaire   +2 more sources

Engineered Halomonas spp. for production of l-Lysine and cadaverine

Bioresource Technology, 2022
Cadaverine, a derivative of l-lysine, has been used as a monomer for the synthesis of bio-based nylon-5,6. This study engineered Halomonas bluephagenesis TD1.0 by blocking the feedback inhibition, overexpressing the key l-lysine synthesis genes, strengthening the l-lysine export system and increasing the supply of oxaloacetate for production of l ...
Cuihuan, Zhao, Taoran, Zheng, Yinghao, Feng, Xuan, Wang, Lizhan, Zhang, Qitiao, Hu, Jinchun, Chen, Fuqing, Wu, Guo-Qiang, Chen   +8 more
openaire   +2 more sources

Analysis of the Genome of the Moderate Halophile Halomonas eurihalina

Current Microbiology, 2002
We have studied the genomic organization of Halomonas eurihalina, a moderately halophilic bacterium that produces an anionic exopolysaccharide with a potentially wide range of applications in industry. To estimate the genome size of strain F2-7, large restriction fragments of genomic DNA were separated by pulsed-field gel electrophoresis.
Inmaculada, Llamas, Maria José, Sánchez, Montserrat, Argandoña, Victoria, Béjar, Emilia, Quesada, Ana, del Moral   +5 more
openaire   +2 more sources

Manipulation of polyhydroxyalkanoate granular sizes in Halomonas bluephagenesis

Metabolic Engineering, 2019
Bacterial polyhydroxyalkanoates (PHA) are a family of intracellular polyester granules with sizes ranging from 100 to 500 nm. Due to their small sizes, it has been very difficult to separate the PHA granules from the bacterial broths. This study aims to engineer the PHA size control mechanism to obtain large PHA granular sizes beneficial for the ...
Rui, Shen, Zhi-Yu, Ning, Yu-Xuan, Lan, Jin-Chun, Chen, Guo-Qiang, Chen   +4 more
openaire   +2 more sources

Unsterile and continuous production of polyhydroxybutyrate by Halomonas TD01

Bioresource Technology, 2011
An unsterile and continuous fermentation process was developed based on a halophilic bacterium termed Halomonas TD01 isolated from a salt lake in Xinjiang, China. The strain reached 80 g/L cell dry weight containing 80% poly(3-hydroxybutyrate) (PHB) on glucose salt medium during a 56 h fed-batch process.
Dan, Tan, Yuan-Sheng, Xue, Gulsimay, Aibaidula, Guo-Qiang, Chen   +3 more
openaire   +2 more sources

Turgor regulation in a novel Halomonas species

Archives of Microbiology, 1993
The mechanisms by which a novel eubacterium, identified as belonging to the genus Halomonas, adapted to increases in the extracellular osmotic potential were investigated. It was shown that the ability of the bacterium to grow after hyperosmotic shock was dependent on the presence of potassium ions.
Stephen P. Cummings, Michael P. Williamson, D. James Gilmour   +2 more
openaire   +1 more source