Calibrating a functional assay for variant classification in RYR1-related malignant hyperthermia susceptibility. [PDF]
Ying EZ +7 more
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Magnetic Resonance Imaging of Progressive Changes in Traumatic Brain Injury and Epileptogenesis (Aivomuutosten magneettikuvantaminen traumaattisen päävamman ja epilepsian kehitysvaiheiden aikana) [PDF]
Immonen, Riikka
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Myocardial injury and its prevention in the perioperative setting [PDF]
Foëx, P., Schaub, M. C., Zaugg, M.
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A review of preclinical research on mechanically gated ion channels as therapeutic targets in neuropathic pain. [PDF]
Xie Y, Wang X, Ju J, Hang L.
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Systematic analysis of adverse reactions associated with dantrolene treatment: From clinical features to molecular mechanisms. [PDF]
Chen H, Zhang X, Chen D, Jiang X, Yu C.
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Comprehensive profiling of anaesthetised brain dynamics across phylogeny
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Effects of the halothane-sensitivity gene on sarcoplasmic reticulum function
American Journal of Physiology - Cell Physiology, 1989Pigs heterozygous for the halothane-sensitivity gene exhibit a distinct phenotype with regard to both in vivo and in vitro muscle responses to halothane (E. M. Gallant, J. R. Mickelson, B. D. Roggow, S. K. Donaldson, C. F. Louis, and W. E. Rempel. Am. J. Physiol. 257 (Cell Physiol. 26): C781-C786, 1989). In this paper heavy sarcoplasmic reticulum (SR)
James Mickelson
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Halothane-sensitivity gene and muscle contractile properties in malignant hyperthermia
American Journal of Physiology - Cell Physiology, 1989Malignant hyperthermia (MH) results from the presence of the halothane-sensitivity gene and is characterized by abnormalities in muscle function. Populations of genetically defined pigs were used to determine the in vivo and in vitro expression of this gene in both the homozygous and the heterozygous condition.
James Mickelson
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Halothane anesthesia suppresses reflex tachycardia caused by calcitonin gene-related peptide in dogs
Journal of Anesthesia, 1996Calcitonin gene-related peptide (CGRP) is known to produce vasodilation, hypotension, and tachycardia. To investigate the interaction between CGRP and anesthetics, the hemodynamic response to infusions of CGRP was studied in dogs anesthetized with halothane or pentobarbital.
S, Takeda +3 more
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