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Calibrating a functional assay for variant classification in RYR1-related malignant hyperthermia susceptibility. [PDF]

open access: yesHum Mol Genet
Ying EZ   +7 more
europepmc   +1 more source

Comprehensive profiling of anaesthetised brain dynamics across phylogeny

open access: yes
Luppi AI   +26 more
europepmc   +1 more source
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Effects of the halothane-sensitivity gene on sarcoplasmic reticulum function

American Journal of Physiology - Cell Physiology, 1989
Pigs heterozygous for the halothane-sensitivity gene exhibit a distinct phenotype with regard to both in vivo and in vitro muscle responses to halothane (E. M. Gallant, J. R. Mickelson, B. D. Roggow, S. K. Donaldson, C. F. Louis, and W. E. Rempel. Am. J. Physiol. 257 (Cell Physiol. 26): C781-C786, 1989). In this paper heavy sarcoplasmic reticulum (SR)
James Mickelson
exaly   +3 more sources

Halothane-sensitivity gene and muscle contractile properties in malignant hyperthermia

American Journal of Physiology - Cell Physiology, 1989
Malignant hyperthermia (MH) results from the presence of the halothane-sensitivity gene and is characterized by abnormalities in muscle function. Populations of genetically defined pigs were used to determine the in vivo and in vitro expression of this gene in both the homozygous and the heterozygous condition.
James Mickelson
exaly   +3 more sources

Halothane anesthesia suppresses reflex tachycardia caused by calcitonin gene-related peptide in dogs

Journal of Anesthesia, 1996
Calcitonin gene-related peptide (CGRP) is known to produce vasodilation, hypotension, and tachycardia. To investigate the interaction between CGRP and anesthetics, the hemodynamic response to infusions of CGRP was studied in dogs anesthetized with halothane or pentobarbital.
S, Takeda   +3 more
exaly   +3 more sources

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