Results 141 to 150 of about 1,139,400 (279)
Robots and Minimal, Physics‐Informed Features: A Hybrid Framework for Enzyme Catalysis
Advanced Science, EarlyView.Robotic experimentation and physics‐informed machine learning combine to predict enzyme substrate scope. With a handful of interpretable features derived from docking and quantum mechanics calculations, our model rivals descriptor‐heavy AI approaches and extrapolates to unseen substrates and enzyme classes.
Natalia Onishchenko +8 more
wiley +1 more source
Sir William Hamilton's account of his first visit to Malta
, 1972 British Museum Egerton 2635, MSS. 13091, f. 86 et seq.William Hamilton's, Britain's Envoy Extraordinary in Naples, accidental visit to Malta in 1769. He was particularly interested in volcanoes and antiquities.
Xuereb, Paul
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Optimal solution of nonlinear equations [PDF]
, 1985 journal articleWe survey recent worst case complexity results for the solution of nonlinear equations. Notes on worst and average case analysis of iterative algorithms and a bibliography of the subject are also ...
Optimal solution; Nonlinear equations +1 more
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Hamilton's 150th Anniversary: Pechakucha 19 - Dave Snell
, 2014 Invited presentation of Bogan research as a part of Pechakucha 19 during of Hamilton's 150th Anniversary Celebrations.
Snell, Dave
core +1 more source
Advanced Science, EarlyView.In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang +18 more
wiley +1 more source
Advanced Science, EarlyView.This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao +12 more
wiley +1 more source
Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair
Advanced Science, EarlyView.Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou +14 more
wiley +1 more source
Riccati differential equations /
, 1972 Includes bibliographical references and index.Front Cover; Riccati Differential Equations; Copyright Page; Contents; Preface; Chapter One. Scalar Riccati Differential Equations; Chapter Two.
Reid, William T.(William Thomas),1907 October 4-1977.
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Advanced Science, EarlyView.Combined high‐glucose and hypoxic stress switches microglia into a TSPAN4‐dependent migrasome‐producing state. These migrasomes deliver pro‐angiogenic signals to endothelial cells, activating HIF‐1α/VEGF signaling, disrupting vascular junctions, and fueling pathological neovascularization. This work uncovers migrasome‐mediated immune‐vascular crosstalk
Jingyi Xu +12 more
wiley +1 more source
Advanced Electronic Materials, EarlyView.Composition‐dependent structural evolution in GeXSe1‐X selector‐only memory (SOM) is correlated with device switching behavior. Increasing Ge strengthens network rigidity, suppresses atomic motion, and stabilizes threshold switching, while narrowing the memory window. The revealed structure–property relationship provides a guideline for compositionally
Tien Anh Nguyen +9 more
wiley +1 more source