Results 71 to 80 of about 1,021,103 (192)

Individualized homeopathic treatment and fluoxetine for moderate to severe depression in peri- and postmenopausal women (HOMDEP-MENOP study): a randomized, double-dummy, double-blind, placebo-controlled trial.

PLoS ONE, 2015
BackgroundPerimenopausal period refers to the interval when women's menstrual cycles become irregular and is characterized by an increased risk of depression.
Emma Del Carmen Macías-Cortés, Lidia Llanes-González, Leopoldo Aguilar-Faisal, Juan Asbun-Bojalil   +3 more
doaj   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

Continuous‐Flow Microfluidic Synthesis Enhances C2+ Selectivity for Cu2O Catalysts

Advanced Science, EarlyView.
Microfluidic devices are used to prepare Cu2O nanoparticles under laminar flow conditions, which exhibit enhanced selectivity in the CO2‐to‐C2+ reaction due to their nanoporosity and high defect concentration. Cu2O prepared using standard solution methods displays decreased CO2‐to‐C2+ selectivity due to the absence of similar properties. Altogether, we
Carlota Casas, Anh Tuan Ngo, João Pedro Vale, Ona Falcó, Gerard Martí, Mohamed Amazian, Júlia Mayans, Sònia Estradé, Marcos Gil‐Sepulcre, Teresa Andreu, Francesca Peiró, Tiago Sotto Mayor, Lluís Yedra, Jordi García‐Antón, Josep Puigmartí‐Luis, Xavier Sala, Roc Matheu   +16 more
wiley   +1 more source

TET1 Inhibition Promotes Therapeutic Sensitivity in TP53‐Mutant GBM by Influencing Genome Fragility and Altering TAMs Biology

Advanced Science, EarlyView.
In TP53mut GBM cells, reduced P53 function is associated with increased TET1 expression. Genetic or pharmacological inhibition of TET1 correlates with genome fragility, including DNA damage, cellular senescence, telomere shortening, and reactive oxygen species accumulation, which may contribute to increased efficacy of antitumor therapy.
Zhuonan Pu, Jinqiu Liu, Yuxuan Deng, Shuyu Hao, Xiaoli Zhang, Mingxu Yang, Chao Guo, Chao Du, Yingdan Chen, Tai Sun, Nan Ji, Zhengping Zhuang, Jie Feng   +12 more
wiley   +1 more source

Efficacy and safety of rimegepant in Chinese women with pure menstrual migraine: a retrospective observational study

BMC Neurology
Objective To evaluate rimegepant’s effectiveness and safety in the short-term prevention of pure menstrual migraine. Background Rimegepant’s effectiveness and safety in both acute and preventive treatment of migraine have been demonstrated by numerous ...
Wenlu Ye, Yongli Fan, Jia Liu, Xuan Xu, Xing Xu, Dan Li, Juan Liu, Yixian Huang   +7 more
doaj   +1 more source

CLOCK 3111T/C Variant Correlates with Motor Fluctuation and Sleep Disorders in Chinese Patients with Parkinson’s Disease

Parkinson's Disease, 2018
Background. The clock genes controlling biological rhythm play an important role in the pathophysiology of aging. The purpose of this study was to determine whether there is an association between a variant of the circadian locomotor output cycles kaput (
Fan Lou, Ming Li, Xiaoguang Luo, Yan Ren
doaj   +1 more source

HUBUNGAN KARAKTERISTIK KELUARGA DENGAN TINGKAT ANSIETAS SAAT MENGHADAPI KEKAMBUHAN PASIEN GANGGUAN JIWA

Indonesian Journal for Health Sciences, 2018
Clients mental disorder characterized by cycles of recurrence, which reached 60-75% of all patients. Recurrence trigger psychological conflict such as anxiety in the family.
Livana PH, Yulia Susanti, Dimas Eka Ardika Putra   +2 more
doaj   +1 more source

A Selected Catalog of the Ezra Pound Collection at Hamilton College

, 2005
This lavishly illustrated catalog highlights the Hamilton College Library’s holdings of Ezra Pound material. Pound, a Hamilton alumnus (class of 1905), was one of the most important and influential poets of the twentieth century.
McWhirter, Cameron, Ericson, Randall L.
core  

Second Nature: Hamilton College and the Natural Environment [PDF]

, 2017
The following histories explore the boundaries between the human and natural environment on Hamilton College’s campus. They were written for the Environmental Studies course “Interpreting the American Environment” and incorporated site visits and ...
Raynor, Emma, \u2718, Connors, Noelle, \u2719, Morgan, Emma, \u2718, Boutselis, Sabrina, \u2719, Keating, Chloe, \u2718, Simons, Peter, Kwasnoski, Laura, \u2718, Hay, Jack, \u2719, LePage, Elise, \u2718, Preston, Leigh, \u2718   +9 more
core  

Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations

Advanced Science, EarlyView.
Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford, Matthew Tamasi, Elena Di Mare, Adam J. Gormley   +3 more
wiley   +1 more source