Results 11 to 20 of about 206,174 (219)

The role of photoperiod and melatonin in the control of seasonal reproduction in mammals [PDF]

open access: yesRoczniki Naukowe Polskiego Towarzystwa Zootechnicznego, 2020
Melatonin secreted by pineal cells is a hormone whose biosynthesis is coordinated by neurons of the master clock located in the hypothalamic suprachiasmatic nuclei (SCN), characterized by the generation of a 24-hour rhythm.
Izabela Szpręgiel, Danuta Wronska
doaj   +1 more source

Defining the Syrian hamster as a highly susceptible preclinical model for SARS-CoV-2 infection

open access: yesEmerging Microbes and Infections, 2020
Following emergence in late 2019, SARS-CoV-2 rapidly became pandemic and is presently responsible for millions of infections and hundreds of thousands of deaths worldwide.
K. Rosenke   +15 more
semanticscholar   +2 more sources

Adenovirus type 5 SARS-CoV-2 vaccines delivered orally or intranasally reduced disease severity and transmission in a hamster model

open access: yesScience Translational Medicine, 2022
Transmission-blocking strategies that slow the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and protect against coronavirus disease 2019 (COVID-19) are needed.
S. Langel   +10 more
semanticscholar   +1 more source

Dynamic Changes of the Blood Chemistry in Syrian Hamsters Post-Acute COVID-19

open access: yesMicrobiology Spectrum, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that causes coronavirus disease 2019 (COVID-19). However, the long-term health consequences of COVID-19 are not fully understood. We aimed to determine the long-term lung
Chi-Ju Hsu   +9 more
doaj   +1 more source

Gender associates with both susceptibility to infection and pathogenesis of SARS-CoV-2 in Syrian hamster

open access: yesSignal Transduction and Targeted Therapy, 2021
Epidemiological studies of the COVID-19 patients have suggested the male bias in outcomes of lung illness. To experimentally demonstrate the epidemiological results, we performed animal studies to infect male and female Syrian hamsters with SARS-CoV-2 ...
Lunzhi Yuan   +24 more
semanticscholar   +1 more source

Reversible Suppression of Fear Memory Recall by Transient Circadian Arrhythmia

open access: yesFrontiers in Integrative Neuroscience, 2022
We tested the hypothesis that a temporary period of circadian arrhythmia would transiently impair recall of an aversive memory in Siberian hamsters (Phodopus sungorus).
Athreya Steiger   +5 more
doaj   +1 more source

Splenic Transcriptional Responses in Severe Visceral Leishmaniasis: Impaired Leukocyte Chemotaxis and Cell Cycle Arrest

open access: yesFrontiers in Immunology, 2021
Structural changes in the spleen have been reported in several infectious diseases. In visceral leishmaniasis (VL), a severe parasitic disease caused by Leishmania spp., the loss of white pulp accompanies a severe clinical presentation.
Caroline Vilas Boas de Melo   +11 more
doaj   +1 more source

Suppression of Circadian Timing and Its Impact on the Hippocampus

open access: yesFrontiers in Neuroscience, 2021
In this article, I describe the development of the disruptive phase shift (DPS) protocol and its utility for studying how circadian dysfunction impacts memory processing in the hippocampus.
Norman F. Ruby
doaj   +1 more source

Simulation of the clinical and pathological manifestations of Coronavirus Disease 2019 (COVID-19) in golden Syrian hamster model: implications for disease pathogenesis and transmissibility

open access: yesClinical Infectious Diseases, 2020
Background A physiological small animal model that resembles COVID-19 with low mortality is lacking. Methods Molecular docking on the binding between angiotensin-converting enzyme 2 (ACE2) of common laboratory mammals and the receptor-binding domain of ...
J. Chan   +23 more
semanticscholar   +1 more source

Antiviral Ranpirnase TMR-001 Inhibits Rabies Virus Release and Cell-to-Cell Infection In Vitro

open access: yesViruses, 2020
Currently, no rabies virus-specific antiviral drugs are available. Ranpirnase has strong antitumor and antiviral properties associated with its ribonuclease activity.
Todd G. Smith   +12 more
doaj   +1 more source

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