Results 241 to 250 of about 162,987 (311)

Multitarget Drug Design for Cardiovascular Disease: Bridging Chemistry and Medicine

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
Many pathophysiological pathways associated with cardiovascular diseases involve multiple drug targets. This article reviews recent advances in the development of pharmacological compounds capable of simultaneously modulating multiple mechanisms. Multitarget drugs offer a promising therapeutic approach for complex cardiovascular disorders, including ...
Gyuzel Y. Mitronova, Vladimir N. Belov, Constanze Schmidt, Stephan E. Lehnart   +3 more
wiley   +1 more source

Nipah Virus: A Neurotropic Zoonosis-From Molecular Biology to Clinical Manifestations and Translational Advances. [PDF]

Viruses
Mariappan V, Feldmann H.
europepmc   +1 more source

Hitting Coronaviruses Where It Hurts: Antiviral Strategies Targeting Viral Proteins

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
Viral proteins represent key vulnerabilities in human coronaviruses (HCoVs). This review outlines inhibitors targeting spike (S), main protease (Mpro), papain‐like protease (PLpro), and RNA‐dependent RNA polymerase (RdRp), mapping chemically diverse strategies that disrupt entry and replication, and provides an integrated view of current candidates ...
Álvaro de la Cruz‐Potenciano, Miguel Maldonado, María‐José Camarasa, Sonia de Castro   +3 more
wiley   +1 more source

Babesia microti: Breaking the culture barrier. [PDF]

Trends Parasitol
Vydyam P, Beri D, Lobo CA.
europepmc   +1 more source

Curcumin-based compounds in non-malignant biliary injury and cholangiocarcinoma: mechanistic insights and translational barriers. [PDF]

Front Pharmacol
Chen Z, Peng T.
europepmc   +1 more source

Physics-informed Hamiltonian learning for large-scale optoelectronic property prediction. [PDF]

Nat Commun
Schwade M, Zhang S, Vonhoff F, Delgado FP, Egger DA.   +4 more
europepmc   +1 more source

Comparative osteogenic performance of Chinese hamster ovary cell-derived versus Escherichia coli-derived recombinant human bone morphogenetic protein-2. [PDF]

Bone Joint Res
Matthews C, Johnson L, Holden W, von Benecke J.   +3 more
europepmc   +1 more source

Head of the Syrian Hamster (<i>Mesocricetus auratus</i>): Planar Anatomy with Correlative Micro-Computed Tomography and Magnetic Resonance Imaging. [PDF]

Animals (Basel)
Nourinezhad J, Ansari S, Moarabi A, Hanafi MG, Janeczek M.   +4 more
europepmc   +1 more source

The Effect of Serum Carnosinase on the Tissue Distribution of Imidazole Dipeptides After Their Oral Administration in Golden Hamsters. [PDF]

Nutrients
Shiotani S, Kawashima T, Takahashi C, Sakano T, Kuramoto A, Yanai N.   +5 more
europepmc   +1 more source