Results 261 to 270 of about 399,690 (387)

Adsorption of antigen to polymeric nanoparticles enhances cytotoxic T‐cell responses and anti‐tumor immunity by targeting conventional type 1 dendritic cells

Immunology &Cell Biology, EarlyView.
Therapeutic cancer vaccines require CD8+ T‐cell activation for efficacy. This response can be enhanced by rationally designing polymeric nanoparticle adjuvants. The importance of antigen location for the adjuvanticity of polymeric nanoparticles has not been fully resolved.
Jorge Huete‐Carrasco, Jingjing Zhu, Benoit J Van den Eynde, Christian Thomas Mayer, Tim Sparwasser, Ross W Ward, Ed C Lavelle   +6 more
wiley   +1 more source

Hamsters with long COVID present distinct transcriptomic profiles associated with neurodegenerative processes in brainstem. [PDF]

Nat Commun
Coleon A, Larrous F, Kergoat L, Tichit M, Hardy D, Obadia T, Kornobis E, Bourhy H, de Melo GD.   +8 more
europepmc   +1 more source

Innate Immune Activation Is a Strong Suppressor of CCL22 and Impedes Regulatory T Cell–Dendritic Cell Interaction

Immunology, EarlyView.
During homeostasis, CCL22 is secreted by dendritic cells (DC), which mediate contacts between regulatory T cells (Treg) and DC to maintain immune balance. Activation of innate immunity via microbes or pattern recognition receptor (PRR) agonists induces the secretion of several soluble factors (e.g., type I and II interferons, IL‐10), which mediate ...
Ignazio Piseddu, Jan Gärtig, Stephan Eiber, Stefan Moder, Raffael Thaler, Matthias Thaler, Juliane Gruen, Marlies Vornhülz, Kevin Bahner, Luana Messa, Benjamin Kühnemuth, Jennifer Müller, Konstantin Schnell, Antonia Beimert, Carolin Perleberg, Natascha Röhrle, Maximilian Martin Ludwig Knott, Linda Hammann, Vanessa Wittmann, Patrick Layritz, Moritz Rapp, Carole Bourquin, Julia Mayerle, Stefan Endres, David Anz   +24 more
wiley   +1 more source

Identification of potent inhibitors of Leishmania donovani and Leishmania infantum chagasi, the causative agents of Old and New World visceral leishmaniasis. [PDF]

Commun Biol
Zulfiqar B, Colombo FA, Nunes JB, Espuri PF, Ferreira AF, Manthri S, De Rycker M, Marques MJ, Avery VM.   +8 more
europepmc   +1 more source

Pretreatment of recipients (nude rat) with donor antigens leads to prolonged survival of hamster heart xenografts [PDF]

, 1996
Demetris, AJ, Fung, JJ, Madariaga, J, Pan, F, Rao, AS, Starzl, TE, Sun, H, Tsugita, M, Valdivia, LA, Wakizaka, Y   +9 more
core  

Vascular Patterns of Four Transplantable Tumors in the Hamster (Mesocricetus Auratus) [PDF]

, 1965
C. M. Goodall, Rebecca L. Feldman, A. G. Sanders, Philippe Shubik   +3 more
openalex   +1 more source

Disrupted circadian rhythms and opioid‐mediated adverse effects: Bidirectional relationship and putative mechanisms

Journal of Neuroendocrinology, EarlyView.
Abstract Recent studies have shown a link between disrupted circadian rhythms and the development of chronic opioid‐induced negative effects. Both animal and human studies show a significant bidirectional relationship between the circadian system and opioid effects.
Nasrin Mehranfard, Maedeh Ghasemi, Ehsan Saboory   +2 more
wiley   +1 more source

The furin cleavage site is required for pathogenesis, but not transmission, of SARS-CoV-2. [PDF]

J Virol
Morgan AL, Vu MN, Zhou Y, Lokugamage KG, Meyers WM, Alvarado RE, Ahearn Y, Estes LK, Plante JA, Johnson BA, Suthar MS, Walker DH, Plante KS, Menachery VD.   +13 more
europepmc   +1 more source

Immunity to a salivary protein of a sand fly vector protects against the fatal outcome of visceral leishmaniasis in a hamster model

Proceedings of the National Academy of Sciences of the United States of America, 2008
R. Gomes, C. Teixeira, M. Teixeira, Fabiano Oliveira, M. J. Menezes, C. Silva, C. D. de Oliveira, J. Miranda, D. Elnaiem, S. Kamhawi, J. Valenzuela, C. Brodskyn   +11 more
semanticscholar   +1 more source

Stress alters hypothalamic gene expression in adolescent male Golden hamsters

Journal of Neuroendocrinology, EarlyView.
Abstract In Golden hamsters (Mesocricetus auratus), a two‐week exposure to chronic social stress in adolescence causes acceleration of agonistic behavior, enhanced adult aggression, impaired waiting impulsivity, and higher food intake, body fat, and long‐term increased body weight.
Kevin M. Moran, Tyler M. Milewski, James P. Curley, Yvon Delville   +3 more
wiley   +1 more source