Results 21 to 30 of about 306,860 (343)

A combination DNA vaccine encoding nucleoside hydrolase 36 and glycoproteine 63 protects female but not male hamsters against Leishmania mexicana

Parasite, 2009
Leishmaniasis is a group of diseases caused by protozoan parasites of the Leishmania genus. Previous studies have shown that a DNA vaccine encoding Leishmania donovani antigen nucleoside hydrolase 36 and L. mexicana glycoprotein 63 is protective in mice.
Chalé-balboa W.G., Mut-Martin M., Ramirez-Sierra M.J., Garcia-Miss M.R., Dumonteil E.   +4 more
doaj   +1 more source

Convalescent human IgG, but not IgM, from COVID-19 survivors confers dose-dependent protection against SARS-CoV-2 replication and disease in hamsters

Frontiers in Immunology, 2023
IntroductionAntibody therapeutic strategies have served an important role during the COVID-19 pandemic, even as their effectiveness has waned with the emergence of escape variants.
Hannah A. D. King, Hannah A. D. King, Hannah A. D. King, Vincent Dussupt, Vincent Dussupt, Vincent Dussupt, Letzibeth Mendez-Rivera, Letzibeth Mendez-Rivera, Letzibeth Mendez-Rivera, Bonnie M. Slike, Bonnie M. Slike, Bonnie M. Slike, Ursula Tran, Ursula Tran, Ursula Tran, Nathan D. Jackson, Nathan D. Jackson, Nathan D. Jackson, Erica Barkei, Michelle Zemil, Michelle Zemil, Michelle Zemil, Emily Tourtellott-Fogt, Emily Tourtellott-Fogt, Emily Tourtellott-Fogt, Caitlin H. Kuklis, Sandrine Soman, Aslaa Ahmed, Maciel Porto, Christopher Kitajewski, Brittany Spence, Dalia Benetiene, Lindsay Wieczorek, Lindsay Wieczorek, Lindsay Wieczorek, Swagata Kar, Gregory Gromowski, Victoria R. Polonis, Shelly J. Krebs, Shelly J. Krebs, Shelly J. Krebs, Kayvon Modjarrad, Diane L. Bolton, Diane L. Bolton, Diane L. Bolton   +44 more
doaj   +1 more source

Immunocytochemical localization of chromatin regions UV-microirradiated in S phase or anaphase : Evidence for a territorial organization of chromosomes during cell cycle of cultured Chinese hamster cells [PDF]

, 1983
Chinese hamster cells (M3-1 line) in S phase were laser-UV-microirradiated (λ, 257 nm) at a small site of the nucleus. Cells were fixed either immediately thereafter or in subsequent stages of the cell cycle, including prophase and metaphase.
Avivi, Bennett, Berns, Boveri, Boveri, Comings, Cornelis, Cornelis, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Earnshaw, Gray, Hager, Hancock, Hancock, Hens, Laemmli, Rabl, Regan, Sakharov, Sedat, Sperling, Stack, Trosko, Vogel, Zorn   +33 more
core   +1 more source

Flagellum and toxin phase variation impacts intestinal colonization and disease development in a mouse model of Clostridioides difficile infection

Gut Microbes, 2022
Clostridioides difficile is a major nosocomial pathogen that can cause severe, toxin-mediated diarrhea and pseudomembranous colitis. Recent work has shown that C. difficile exhibits heterogeneity in swimming motility and toxin production in vitro through
Dominika Trzilova, Mercedes A. H. Warren, Nicole C. Gadda, Caitlin L. Williams, Rita Tamayo   +4 more
doaj   +1 more source

A point mutation of integrin beta 1 subunit blocks binding of alpha 5 beta 1 to fibronectin and invasin but not recruitment to adhesion plaques. [PDF]

, 1992
A point mutation in a highly conserved region of the beta 1 subunit, Asp130 to Ala (D130A) substitution, abrogates the Arg-Gly-Asp (RGD)-dependent binding of alpha 5 beta 1 to fibronectin (FN) without disrupting gross structure or heterodimer assembly ...
Ginsberg, MH, Mandelman, D, Puzon, W, Takada, Y, Ylänne, J   +4 more
core   +2 more sources

Neural Androgen Synthesis and Aggression: Insights From a Seasonally Breeding Rodent

Frontiers in Endocrinology, 2018
Aggression is an essential social behavior that promotes survival and reproductive fitness across animal systems. While research on the neuroendocrine mechanisms underlying this complex behavior has traditionally focused on the classic neuroendocrine ...
Kathleen M. Munley, Nikki M. Rendon, Gregory E. Demas   +2 more
doaj   +1 more source

Population dynamics and biotopic distribution of the common hamster in Medobory (Podillia)

Theriologia Ukrainica, 2022
The results of the surveys and data on biotopic distribution of common hamster burrows in the vicinity of the Medobory Nature Reserve were collected and summarised.
Ivan Dobryvoda
doaj   +1 more source

Role of spike compensatory mutations in the interspecies transmission of SARS-CoV-2

One Health, 2022
SARS-CoV-2, the virus responsible for COVID-19 in humans, can efficiently infect a large number of animal species. Like any virus, and particularly RNA viruses, SARS-CoV-2 undergoes mutations during its life cycle some of which bring a selective ...
Roger Frutos, Nouara Yahi, Laurent Gavotte, Jacques Fantini, Christian A. Devaux   +4 more
doaj   +1 more source

Evidence for the role of proteoglycans in cation-mediated gene transfer [PDF]

, 1996
We report evidence that gene complexes, consisting of polycations and plasmid DNA enter cells via binding to membrane-associated proteoglycans. Treatment of HeLa cells with sodium chlorate, a potent inhibitor of proteoglycan sulfation, reduced luciferase
Baldeschwieler, John D., Mislick, Kimberly A.   +1 more
core   +1 more source

Hamster health care

BMJ, 2000
Across the globe doctors are miserable because they feel like hamsters on a treadmill. They must run faster just to stand still. In underdoctored Britain they must see ever more patients, fill in more forms, and sit on more committees just to keep the NHS afloat.
Richard Smith, Ian Morrison
openaire   +4 more sources