Results 21 to 30 of about 259,291 (341)

Genomic characterization, transcriptome analysis, and pathogenicity of the Nipah virus (Indian isolate)

open access: yesVirulence, 2023
Nipah virus (NiV) is a high-risk pathogen which can cause fatal infections in humans. The Indian isolate from the 2018 outbreak in the Kerala state of India showed ~ 4% nucleotide and amino acid difference in comparison to the Bangladesh strains of NiV ...
Sreelekshmy Mohandas   +5 more
doaj   +1 more source

Characterizations of Hamster Retina as a Model for Studies of Retinal Cholesterol Homeostasis

open access: yesBiology, 2021
Cholesterol homeostasis in the retina, a sensory organ in the back of the eye, has been studied in mice but not hamsters, despite the latter being more similar to humans than mice with respect to their whole-body cholesterol maintenance. The goal of this
Nicole El-Darzi   +6 more
doaj   +1 more source

BORAGE OIL RICH IN GAMMA LINOLENIC ACID (GLA) REDUCES CARDIOVASCULAR DISEASE (CVD) RISK FACTORS IN HAMSTERS FED IN DIET RICH IN SATURATED FATTY ACIDS (SFAS) AND CHOLESTEROL. [PDF]

open access: yesBasrah Journal of Veterinary Research, 2014
The experiment was applied on /45/ healthy male of golden Syrian hamsters, were divided into three groups as follows: Control group(C), High Fat-High Cholesterol group(HF-HC) and Borage Oil group (BO).
Ahmad Mufeed Supuh   +2 more
doaj   +1 more source

Diet-Induced Obesity and NASH Impair Disease Recovery in SARS-CoV-2-Infected Golden Hamsters

open access: yesViruses, 2022
Obese patients with non-alcoholic steatohepatitis (NASH) are prone to severe forms of COVID-19. There is an urgent need for new treatments that lower the severity of COVID-19 in this vulnerable population. To better replicate the human context, we set up
François Briand   +18 more
doaj   +1 more source

Antiviral Ranpirnase TMR-001 Inhibits Rabies Virus Release and Cell-to-Cell Infection In Vitro

open access: yesViruses, 2020
Currently, no rabies virus-specific antiviral drugs are available. Ranpirnase has strong antitumor and antiviral properties associated with its ribonuclease activity.
Todd G. Smith   +12 more
doaj   +1 more source

A combination DNA vaccine encoding nucleoside hydrolase 36 and glycoproteine 63 protects female but not male hamsters against Leishmania mexicana

open access: yesParasite, 2009
Leishmaniasis is a group of diseases caused by protozoan parasites of the Leishmania genus. Previous studies have shown that a DNA vaccine encoding Leishmania donovani antigen nucleoside hydrolase 36 and L. mexicana glycoprotein 63 is protective in mice.
Chalé-balboa W.G.   +4 more
doaj   +1 more source

Syrian Hamster as an Animal Model for the Study on Infectious Diseases

open access: yesFrontiers in Immunology, 2019
Infectious diseases still remain one of the biggest challenges for human health. In order to gain a better understanding of the pathogenesis of infectious diseases and develop effective diagnostic tools, therapeutic agents, and preventive vaccines, a ...
Jinxin Miao   +3 more
semanticscholar   +1 more source

Convalescent human IgG, but not IgM, from COVID-19 survivors confers dose-dependent protection against SARS-CoV-2 replication and disease in hamsters

open access: yesFrontiers in Immunology, 2023
IntroductionAntibody therapeutic strategies have served an important role during the COVID-19 pandemic, even as their effectiveness has waned with the emergence of escape variants.
Hannah A. D. King   +44 more
doaj   +1 more source

Neural Androgen Synthesis and Aggression: Insights From a Seasonally Breeding Rodent

open access: yesFrontiers in Endocrinology, 2018
Aggression is an essential social behavior that promotes survival and reproductive fitness across animal systems. While research on the neuroendocrine mechanisms underlying this complex behavior has traditionally focused on the classic neuroendocrine ...
Kathleen M. Munley   +2 more
doaj   +1 more source

Flagellum and toxin phase variation impacts intestinal colonization and disease development in a mouse model of Clostridioides difficile infection

open access: yesGut Microbes, 2022
Clostridioides difficile is a major nosocomial pathogen that can cause severe, toxin-mediated diarrhea and pseudomembranous colitis. Recent work has shown that C. difficile exhibits heterogeneity in swimming motility and toxin production in vitro through
Dominika Trzilova   +4 more
doaj   +1 more source

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