Results 41 to 50 of about 206,174 (219)

A Syrian golden hamster model recapitulating ebola hemorrhagic fever.

open access: yesJournal of Infectious Diseases, 2013
Ebola hemorrhagic fever (EHF) is a severe viral infection for which no effective treatment or vaccine is currently available. While the nonhuman primate (NHP) model is used for final evaluation of experimental vaccines and therapeutic efficacy, rodent ...
H. Ebihara   +10 more
semanticscholar   +1 more source

Protection of hamsters from mortality by reducing fecal moxifloxacin concentration with DAV131A in a model of moxifloxacin-induced Clostridium difficile colitis [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, American Society for Microbiology, 2017, 2017
BackgroundLowering the gut exposure to antibiotics during treatments can prevent microbiota disruption. We evaluated the effect of an activated charcoal-based adsorbent, DAV131A, on fecal free moxifloxacin concentration and mortality in a hamster model of moxifloxacin-induced C.
arxiv   +1 more source

Age-Associated Metabolic and Morphologic Changes in Mitochondria of Individual Mouse and Hamster Oocytes

open access: yesPLoS ONE, 2013
Background In human oocytes, as in other mammalian ova, there is a significant variation in the pregnancy potential, with approximately 20% of oocyte-sperm meetings resulting in pregnancies.
F. simsek‐duran   +5 more
semanticscholar   +1 more source

Hypothalamic Ventricular Ependymal Thyroid Hormone Deiodinases Are an Important Element of Circannual Timing in the Siberian Hamster (Phodopus sungorus)

open access: yesPLoS ONE, 2013
Exposure to short days (SD) induces profound changes in the physiology and behaviour of Siberian hamsters, including gonadal regression and up to 30% loss in body weight.
A. Herwig   +7 more
semanticscholar   +1 more source

Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant

open access: yesNature, 2022
The emergence of the Omicron variant of SARS-CoV-2 is an urgent global health concern1. In this study, our statistical modelling suggests that Omicron has spread more rapidly than the Delta variant in several countries including South Africa.
R. Suzuki   +77 more
semanticscholar   +1 more source

Quantitative characterizations of the cholesterol-related pathways in the retina and brain of hamsters

open access: yesJournal of Lipid Research, 2023
The retina and brain are separated from the systemic circulation by the anatomical barriers, which are permeable (the outer blood-retinal barrier) and impermeable (the blood-brain and inner blood-retina barriers) to cholesterol.
Natalia Mast   +3 more
doaj  

Stimulatory effect of RFRP-3 on the gonadotrophic axis in the male Syrian hamster: the exception proves the rule.

open access: yesEndocrinology, 2012
In seasonal mammals, a distinct photoneuroendocrine circuit that involves the pineal hormone melatonin tightly synchronizes reproduction with seasons. In the Syrian hamster, a seasonal model in which sexual activity is inhibited by short days, we have ...
Caroline M Ancel   +5 more
semanticscholar   +1 more source

Experimental evidence of the genetic hypothesis on the etiology of bicuspid aortic valve aortopathy in the hamster model

open access: yesFrontiers in Cardiovascular Medicine, 2022
Bicuspid aortopathy occurs in approximately 50% of patients with bicuspid aortic valve (BAV), the most prevalent congenital cardiac malformation. Although different molecular players and etiological factors (genetic and hemodynamic) have been suggested ...
María Teresa Soto-Navarrete   +21 more
doaj   +1 more source

Travelling Waves for Reaction-Diffusion Equations Forced by Translation Invariant Noise [PDF]

open access: yes, 2019
Inspired by applications, we consider reaction-diffusion equations on $\mathbb{R}$ that are stochastically forced by a small multiplicative noise term that is white in time, coloured in space and invariant under translations. We show how these equations can be understood as a stochastic partial differential equation (SPDE) forced by a cylindrical Q ...
arxiv   +1 more source

A bioinformatics pipeline for the identification of CHO cell differential gene expression from RNA-Seq data [PDF]

open access: yesMethods Mol Biol. 2017;1603:169-186, 2019
In recent years the publication of genome sequences for the Chinese hamster and Chinese hamster ovary (CHO) cell lines have facilitated study of these biopharmaceutical cell factories with unprecedented resolution. Our understanding of the CHO cell transcriptome, in particular, has rapidly advanced through the application of next-generation sequencing (
arxiv   +1 more source

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