Results 71 to 80 of about 162,987 (311)
Hamster: um rato simples [PDF]
, 2002 This paper describes the robotic agent Hamster witch participated in the Ciber-Rato contest of the Festival Nacional de Robótica 2002. This robot uses a very simple algorithm which is efficient.Este artigo descreve o agente robótico Hamster ...
Silva, Valter, Cardoso, Gonçalo
core +1 more source
SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer
Advanced Science, EarlyView.Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian +8 more
wiley +1 more source
Ultrastructure of Giardia duodenalis trophozoites group from hamster: some relevant aspects
Memorias do Instituto Oswaldo Cruz, 1991 Throphozoites of Giardia duodenalis group obtained from fragments or scratched of hamster's mucosa were examined by transission electron microscopy. The fine structure of the trophozoites are presented and comapred with those described for other animals.
Maria Inês L. Sogayar +1 more
doaj +1 more source
Cannabinoid CB1 Receptor in Nociceptors Mediates Postoperative Analgesia via ASIC3 Inhibition
Advanced Science, EarlyView.CB1R and ASIC3 are co‐expressed in CGRP+ nociceptors of mouse DRG. Plantar incision triggers an upregulation of ASIC3 and activation of ASIC3+ neurons, driving mechanical allodynia. CB1R activation suppresses ASIC3 function and downstream ERK1/2 phosphorylation, thereby braking nociceptive signaling and accelerating pain resolution.
Kangtai Xu +13 more
wiley +1 more source
Innovative Approach Reveals How Receptors Control G Protein State Equilibria
Advanced Science, EarlyView.Using conformational specific trFRET biosensors of the Gi protein (depicted at the bottom), the authors show that receptor activation can not only release GDP from the inactive G protein, but can also release GTP from the activated G protein, leading to the reformation of the RG ternary complex.
Alexandre Bouyssou +12 more
wiley +1 more source
Preclinical Models of Oropouche Virus Infection and Disease
PathogensOropouche virus (OROV) is an emerging and underreported arbovirus with dengue-like symptoms confounding diagnosis. OROV is also neuroinvasive, with a small number of cases presenting severe neurological symptoms.
Daniel Morley +2 more
doaj +1 more source
Advanced Science, EarlyView.In summary, pulmonary exposure to ZnO NPs, particularly aged NPs, promotes breast cancer metastasis by remodelling the lung tumour microenvironment. Aged ZnO NPs enrich M2‐macrophages, MDSCs and activated CAFs to form an immunosuppressive metastatic niche. CXCL10 from these cells drives metastasis via Wnt/β‐catenin activation.
Yong Zhu +8 more
wiley +1 more source
Frontiers in Neuroscience, 2015 Knowledge of neuronal cell types in the mammalian retina is important for the understanding of human retinal disease and the advancement of sight-restoring technology, such as retinal prosthetic devices.
Ian L Jones +7 more
doaj +1 more source
Advanced Science, EarlyView.FDA‐approved anti‐inflammatory drug Auranofin inhibits SARS‐CoV‐2 replication by inhibiting viral Main protease activity and Spike processing required for viral entry. It shows strong synergy with nucleoside analogue Remdesivir, due to non‐overlapping mechanisms.
Oyahida Khatun +13 more
wiley +1 more source