Results 71 to 80 of about 115,928 (265)
Viruses, 2015 Adenovirus infections of immunocompromised pediatric hematopoietic stem cell transplant patients can develop into serious and often deadly multi-organ disease. There are no drugs approved for adenovirus infections.
Karoly Toth +7 more
doaj +1 more source
Advanced Science, EarlyView.This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang +10 more
wiley +1 more source
CCL3 and IL‐7 Synergistically Enhance CAR‐T Efficacy in Solid Tumors
Advanced Science, EarlyView.Synergistic delivery of CCL3 and IL‐7 by CAR‐T cells overcomes the immunosuppressive tumor microenvironment by enhancing cell infiltration, survival, and local immune reprogramming. This also establishes positive feedback that amplifies anti‐tumor activity and memory responses in both CAR‐T and endogenous T cells, presenting a robust therapeutic ...
Huanpeng Chen +12 more
wiley +1 more source
Advanced Science, EarlyView.Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du +9 more
wiley +1 more source
Cell Segmentation Beyond 2D—A Review of the State‐of‐the‐Art
Advanced Intelligent Discovery, EarlyView.Cell segmentation underpins many biological image analysis tasks, yet most deep learning methods remain limited to 2D despite the inherently 3D nature of cellular processes. This review surveys segmentation approaches beyond 2D, comparing 2.5D and fully 3D methods, analyzing 31 models and 32 volumetric datasets, and introducing a unified reference ...
Fabian Schmeisser +6 more
wiley +1 more source
Chromosomes of "Mongoloid" Hamsters.
Experimental Biology and Medicine, 1966 SummaryThe chromosomes were studied in 8 adult Syrian hamsters which had developed “mongolism” following an intracerebral inoculation of virus in the neonatal period. No significant chromosome abnormalities were detected. It is concluded that viral-induced “mongolism” in the hamster is an example of selective postnatal developmental arrest and that the
M, Galton, L, Kilham
openaire +2 more sources
Animal Models and Experimental Medicine, EarlyView.This study established a closed‐tube LAMP‐LFD assay for detecting Rodentibacter heylii and Rodentibacter pneumotropicus. The method exhibited high sensitivity (detection limits of 10−5 ng/μL for R. heylii and 10−4 ng/μL for R. pneumotropicus), high specificity, reliable performance with clinical samples, and effective validation in experimental ...
Huiqiong Yan +17 more
wiley +1 more source
Choline Deficiency in the Hamster
Experimental Biology and Medicine, 1949 SummaryYoung hamsters develop fatty livers when fed choline deficient rations containing peanut meal, although the mean increment in liver fat is only half that found in rats on the same diet. This may be correlated with the finding that hamster livers and kidneys possess markedly less choline oxidase activity than do the livers and kidneys of rats or ...
P, HANDLER, F, BERNHEIM
openaire +2 more sources
mBioHantaviruses are rodent-borne viruses that cause severe disease in infected humans. In the New World, major hantaviruses include Andes virus (ANDV) and Sin Nombre virus (SNV) causing hantavirus pulmonary syndrome.
Rebecca L. Brocato +10 more
doaj +1 more source
Journal of Experimental Pharmacology, 2023 Kongratanapasert T, Kongsomros S, Arya N, et al. J Exp Pharmacol. 2023;15:13–26. Page 19, line two, the text “510.25 ± 329.37 and 2015.74 ± 708.53 μg/g” should read “510.25 ± 329.37 and 2015.74 ...
Kongratanapasert T +18 more
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