Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery +25 more
wiley +1 more source
Randomized controlled trial on the efficacy of topical urea-based cream in preventing capecitabine-associated hand-foot syndrome. [PDF]
Wongkraisri C +5 more
europepmc +1 more source
Hand-foot syndrome induced by chemotherapy drug: Case series study and literature review.
Zaiem A +7 more
europepmc +1 more source
HOPE has improved outcomes in ECD liver transplantation and allowed the safe utilization of increasingly marginal grafts with favorable results. ABSTRACT Background The advent of machine perfusion (MP) has significantly improved post‐liver transplantation (post‐LT) outcomes, potentially enabling the use of increasingly marginal grafts and expanding the
Gerti Dajti +16 more
wiley +1 more source
Discoloration and Dilemma: A Case Report of Hand-Foot Syndrome Associated With Capecitabine Use. [PDF]
Gohil R +4 more
europepmc +1 more source
Spotlight on Hand-Foot Syndrome [PDF]
openaire +1 more source
ABSTRACT Background Postpartum health‐related problems are diverse, and some may extend beyond the first postpartum year. The purpose of this study was to describe women's postpartum health problems in the first and second postpartum years. Methods We analyzed data from an online survey (N = 427) conducted in 2024.
Sudhathai Sirithepmontree +2 more
wiley +1 more source
A phase II study evaluating the preventive effect of topical hydrocortisone for capecitabine-induced hand-foot syndrome in patients with colorectal cancer receiving adjuvant chemotherapy with capecitabine plus oxaliplatin (T-CRACC study). [PDF]
Iimura Y +12 more
europepmc +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source

