Results 71 to 80 of about 2,864,786 (285)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

A Novel Detection and Recognition Method for Continuous Hand Gesture Using FMCW Radar

IEEE Access, 2020
In this article, a novel method for continuous hand gesture detection and recognition is proposed based on a frequency modulated continuous wave (FMCW) radar.
Yong Wang, Aihu Ren, Mu Zhou, Wen Wang, Xiaobo Yang   +4 more
doaj   +1 more source

Multibody Dynamics Model of a Human Hand for Haptics Interaction [PDF]

, 2008
In this paper we propose a strategy for modelling a human hand for Haptics interaction. The strategy consists in a parallel computing architecture that calculates the dynamics of a hand; this is accomplished by computing the dynamics of each finger in a ...
Aracil Santonja, Rafael, Carrera Calderon, Isela Guadalupe, Ferre Pérez, Manuel, Moreno Avalos, Hector, Saltaren Pazmiño, Roque Jacinto, Yime, Eugenio   +5 more
core   +1 more source

Synthesizing Training Data for Object Detection in Indoor Scenes

, 2017
Detection of objects in cluttered indoor environments is one of the key enabling functionalities for service robots. The best performing object detection approaches in computer vision exploit deep Convolutional Neural Networks (CNN) to simultaneously ...
Berg, Alexander C., Georgakis, Georgios, Kosecka, Jana, Mousavian, Arsalan   +3 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Wrist detection based on a minimum bounding box and geometric features

Journal of King Saud University: Computer and Information Sciences, 2020
Wrist detection is a crucial element in the hand-pose estimation and hand-gesture recognition processes in Human-Computer Interaction applications. Most methods use horizontal parallel lines to scan for the location of a wrist line.
Andi Sunyoto, Agus Harjoko, Retantyo Wardoyo, Mochamad Hariadi   +3 more
doaj   +1 more source

Corner Detection of Hand Gesture

TELKOMNIKA Indonesian Journal of Electrical Engineering, 2012
This paper studies the methods of corner detection of hand gesture, and mainly introduces the orthogonal three-direction chain code (3OT) and uses it in corner detection of hand gesture. The study is discussed from four aspects: the techniques used in corner detection, the techniques of Freeman chain code, the main idea of 3OT, the process of corner ...
Linghua Li, Lili Zhang
openaire   +1 more source