Results 71 to 80 of about 2,609,260 (302)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Hand Grip Strength Profiles in Traditional Sumatran Communities: Demographic and Regional Influences

open access: yesHayati Journal of Biosciences
The hand plays a vital role in performing daily tasks with precision, relying on the strength of the hand and forearm muscles. Hand grip strength is widely used as an indicator to assess upper limb muscle performance.
Nur Badriah   +6 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Comparing the Predictive Power of Subjective and Objective Health Indicators: Changes in Hand Grip Strength and Overall Satisfaction with Life as Predictors of Mortality [PDF]

open access: yes
Self-reported measures of health are generally treated as weak measures of respondents' objective health status. On the other hand, most surveys use self-reported health to measure health status and to determine the effects of a range of other socio ...
Gert G. Wagner   +2 more
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Effects of toxoplasmosis, Rh phenotype, hand and trial on performance in the hand-grip test.

open access: yes, 2018
Effects of toxoplasmosis, Rh phenotype, hand and trial on performance in the hand-grip test.
Jaroslav Flegr (52527)   +4 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Video game-based therapy for the non-dominant hand improves manual skills and grip strength [PDF]

open access: yes, 2020
The study was designed to investigate the effect of virtual reality-supported training on manual skills and grip strength in the non-dominant hand in healthy participants. Thirty participants were randomized into two groups: ErgoActive group (n = 15) and
Emir, A.   +8 more
core   +1 more source

Hand-grip strenghts in right- and left-handers with different degrees of hand preferences [PDF]

open access: yes, 2008
We evaluated hand grip- strength in right- and left-handed individuals with different degrees of preferences. Six hundred and thirty-three individuals (343 men, 290 women) aged between 18 and 42 years (22.11±2,07) participated.
Ozer, Cenk Murat   +3 more
core   +1 more source

Hand Grip Strength: age and gender stratified normative data in a population-based study

open access: yesBMC Research Notes, 2011
Background The North West Adelaide Health Study is a representative longitudinal cohort study of people originally aged 18 years and over. The aim of this study was to describe normative data for hand grip strength in a community-based Australian ...
Taylor Anne W   +4 more
doaj   +1 more source

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