Results 81 to 90 of about 2,609,260 (302)

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Dynamometer Measurements of Hand-Grip Strength Predict Multiple Outcomes

, 2001
Hand-grip strength, which can be measured easily and objectively using a dynamometer, is predictive of multiple outcomes among a variety of subjects. Although the literature is not fully consistent, it tends to support grip strength as a predictor of ...
Richard W. Bohannon
core   +1 more source

Hand Grip-EMG Muscle Response [PDF]

, 2014
One of the most important factors in hand-arm system research is the information about hand grip force and pressing force on a tool handle. This article focuses on an alternative method to measure grip force.
Kozupa, A., Barański, R.
core   +1 more source

Hand Grip Strength in the Adult Malaysian Population

Journal of Orthopaedic Surgery, 2006
Purpose. To measure the hand grip strength of Malaysians aged 18 to 65 years. Methods. Between January and April 2003, 412 subjects (200 women and 212 men) were recruited from staff, students, and visitors of the University of Malaya Medical Centre ...
T Kamarul, TS Ahmad, WYC Loh
doaj   +1 more source

Vascular normalization confers an endothelial immune suppressive gene expression profile

Molecular Oncology, EarlyView.
We compare the immunoregulatory gene expression profiles of healthy endothelial cells or endothelial cells from tumors having a normalized endothelium (low leakage) with that of wild‐type tumors (high leakage) and observe that the wild‐type tumor endothelium exhibits immunostimulatory properties.
Liqun He, Michael Welsh
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Hand-grip Strengths in Right- and Left-handers with Different Degrees of Hand Preferences [PDF]

, 2008
We evaluated hand grip- strength in right- and left-handed individuals with different degrees of preferences. Six hundred and thirty-three individuals (343 men, 290 women) aged between 18 and 42 years (22.11 +/- 2.07) participated.
Ozer, Cenk Murat, Sevinc, Ozdemir, Barut, Cagatay, Sumbuloglu, Vildan   +3 more
core   +1 more source

Correlation between handgrip strength and carrying angle in young women with different body mass indices – A cross-sectional observation study

Revista Pesquisa em Fisioterapia
| INTRODUCTION: Hand grip strength is an indicator to predict the health status of individuals in clinical practice. Age, gender, anthropometric characteristics, and health status influence grip strength performance of the hand through their influence on
Kshama Susheel Shetty, Rashmi Ravi Kotennavar, Hariharasudhan Ravichandran   +2 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source