Results 51 to 60 of about 4,564,592 (349)

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

The aetiology of acute traumatic occupational hand injuries seen at a South African state hospital

open access: yes, 2017
Background: Acute traumatic occupational hand injuries are the second most common cause of all traumatic hand injuries worldwide and the most commonly injured body part during occupational accidents.
A. Stewart, G. Biddulph, G. Firth
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Treatment notes: Treatment of hand injuries

open access: yesSouth African Journal of Physiotherapy, 1960
No abstract available.
Joan E. Youthed, Keith Nicol
doaj   +1 more source

Experiences of the High-Velocity Firearm Injuries at the Forearm and Hand [PDF]

open access: yesTurkish Journal of Plastic Surgery, 2017
Objective: Weapon injuries have been increasing due to use of weapons widespread. This study aims to describe our experiences with high-velocity firearm injuries to the forearm and the hand.
Yakup Çil
doaj   +1 more source

Epidemiology of isolated hand injuries in the United Arab Emirates

open access: yesWorld Journal of Orthopaedics, 2016
AIM To provide suggestions for hand injury prevention by study the demography and risk factors of casualties suffering from isolated hand injuries. METHODS All trauma patients with isolated hand injuries who were admitted to Al Ain Hospital for more than
M. Grivna, H. Eid, F. Abu-Zidan
semanticscholar   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

Grinder Injury of the Hand: A Rare but Devastating Occupational Hazard

open access: yesThe Surgery Journal, 2021
Food handlers and workers are exposed to several occupational hazards not frequented by the general population. Grinder injuries of the hand present a devastating consequence of industrial food processing that is infrequently described.
Tushar Patial   +4 more
doaj   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

open access: yesMolecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo   +11 more
wiley   +1 more source

Upper extremity high-pressure injection injuries with paint thinner: Case reports with review of the literature

open access: yesTurkish Journal of Plastic Surgery, 2021
Introduction: High-pressure injection injuries are rare traumas of upper extremity which can result in high morbidity incompatible with presentation.
Bugra Ipek   +5 more
doaj   +1 more source

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