Results 41 to 50 of about 750,742 (319)

Propeller perforator flaps from the dorsal digital artery perforator chain for repairing soft tissue defects of the finger

BMC Surgery, 2019
Background When restoring the appearance and function of the fingers, hand surgeons face a challenge in choosing a suitable surgical method to repair finger skin defects.
Haoliang Hu, Hong Chen, Jinjiong Hong, Weisheng Mao, Mintao Tian, Liping Wang, Jianghui Dong, Xueyuan Li   +7 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Geriatric Proximal Femur Fractures During the Covid-19 Pandemic - Fewer Cases, But More Comorbidities

Geriatric Orthopaedic Surgery & Rehabilitation, 2021
Background: The COVID-19 pandemic is challenging healthcare systems worldwide. This study examines geriatric patients with proximal femur fractures during the COVID-19 pandemic, shifts in secondary disease profile, the impact of the pandemic on ...
Christina Polan, Heinz-Lothar Meyer, Manuel Burggraf, Monika Herten, Paula Beck, Henrik Braitsch, Lars Becker, Carsten Vogel, Marcel Dudda, Max Daniel Kauther   +9 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The rare complication of vascular malformations of the limb after sclerotherapy: a report of 3 cases and brief literature review

BMC Pediatrics, 2023
Background Vascular malformations are common but complicated types of disease in infants, with unclear causes and lack of effective prevention. The symptoms usually do not disappear and tend to progress without medical intervention.
Nianzhe Sun, Rui Liu, Gechang Cheng, Panfeng Wu, Fang Yu, Liming Qing, Lei Zeng, Xiaoyang Pang, Ding Pan, Yongbin Xiao, Umar Zeb Khan, Juyu Tang   +11 more
doaj   +1 more source

Surgery of the hand in severe systemic sclerosis.

, 2004
Ten patients with scleroderma and severe hand problems required surgery, and seven were available for follow-up (two died from scleroderma-related complications and one was lost to follow-up).
Bogoch, E.R., Lee, P., Gilbart, M.K., Jolles, B.M.   +3 more
core   +1 more source

Dermatology and Skin Conditions for Hand Surgeons

, 2022
The hand surgeon must be familiar with all aspects of hand pathology, and while faced with dermatological pathology in daily practice, a comprehensive understanding of skin pathology is often lacking.
Stewart, Nicholas C, Jones, Neil F, Sivakumar, Brahman, Graham, David J   +3 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Comparative study of K-wire combined with screw vs. K-wire in the treatment of AO type B3.1 phalangeal fractures

BMC Musculoskeletal Disorders, 2023
Purpose The purpose of this study was to introduce the surgical method of K-wire combined with screw in the treatment of Arbeitsgemeinschaftfür Osteosynthesefragen (AO) type B3.1 phalangeal fractures and to compare its clinical, radiological and ...
Xuelin Ma, Li Wang, Xiaoran Zhang, Zhemin Zhang, Yali Xu, Li Lv, Xinzhong Shao   +6 more
doaj   +1 more source

Hand transplant surgery [PDF]

The Annals of The Royal College of Surgeons of England, 2014
In September 1998 the world’s first hand transplant was performed in Lyon, France. A new era in reconstructive surgery had begun. This case highlighted the potential for composite tissue allotransplantation (CTA). While CTA is not a new technique, it unifies the principles of reconstructive microsurgery and transplant surgery, achieving the goals of ...
M, Nassimizadeh, A K, Nassimizadeh, D, Power   +2 more
openaire   +2 more sources