Results 51 to 60 of about 18,586 (269)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Robust Face Detection in Airports

EURASIP Journal on Advances in Signal Processing, 2004
Robust face detection in complex airport environment is a challenging task. The complexity in such detection systems stems from the variances in image background, view, illumination, articulation, and facial expression.
Zhang Hong Jiang, Jiang Jimmy Liu, Loe Kia-Fock   +2 more
doaj   +1 more source

Facial Attribute Recognition With Feature Decoupling and Graph Convolutional Networks

IEEE Access, 2019
The objective of facial attribute recognition is to predict a set of labels for each face image. Similar to general multi-label image classification task, facial attribute recognition suffers from several typical problems: discriminative feature learning,
Fudong Nian, Xia Chen, Shimeng Yang, Gang Lv   +3 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Empirical evaluation of data normalization methods for molecular classification [PDF]

PeerJ, 2018
Background Data artifacts due to variations in experimental handling are ubiquitous in microarray studies, and they can lead to biased and irreproducible findings.
Huei-Chung Huang, Li-Xuan Qin
doaj   +2 more sources

Robust Inference via Generative Classifiers for Handling Noisy Labels

, 2019
Accepted in ICML ...
Lee, Kimin, Yun, Sukmin, Lee, Kibok, Lee, Honglak, Li, Bo, Shin, Jinwoo   +5 more
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Good Laboratory Practice in Particle Measurement Calibration: Cascade Impactor

KONA Powder and Particle Journal, 2014
A laboratory often is faced with the task of calibrating particle inertial classifiers or investigating how instruments, or systems, respond to particles of specific sizes.
Virgil A. Marple, Bernard A. Olson
doaj   +1 more source

A comprehensive simulation study on classification of RNA-Seq data. [PDF]

PLoS ONE, 2017
RNA sequencing (RNA-Seq) is a powerful technique for the gene-expression profiling of organisms that uses the capabilities of next-generation sequencing technologies.
Gökmen Zararsız, Dincer Goksuluk, Selcuk Korkmaz, Vahap Eldem, Gozde Erturk Zararsiz, Izzet Parug Duru, Ahmet Ozturk   +6 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source