Results 51 to 60 of about 642,928 (316)

The SuperJournal project : data handling using SGML [PDF]

open access: yes, 1999
The SuperJournal research project evaluated the usage within UK academia of a set of electronic journals made available through a bespoke electronic journal application via the World Wide Web.
MacIntyre, Ross, Apps, Ann
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Expert System for Handling Congestion in Opportunistic Network

open access: yesEAI Endorsed Transactions on Mobile Communications and Applications, 2018
Opportunistic networks are one of the most popular categories of mobile Adhoc networks. These types of networks usually have to deal with intermittent disconnected path from source to the destination most of the time therefor suffers from numerous key ...
Ahthasham Sajid, Khalid Hussain
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Seeking Justice for Indonesian Children: The Juvenile Criminal Justice System in Indonesia in the Context of Criminal Justice Reform

open access: yesIndonesian Journal of Advocacy and Legal Services, 2022
Children who are in contact with law in Indonesia have their own characteristics and handling procedures through the Juvenile Criminal Justice System. Through Law Number 11 of 2021 concerning the Juvenile Criminal Justice System, the state tries to be ...
Resty Shelya Pujiani   +2 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Handling Contractor Safety Concerns/Observations [PDF]

open access: yes, 2018
The University of Maine System\u27s Handling Contractor Safety Concerns ...
University of Maine System
core   +1 more source

Self-modifiable color petri nets for modeling user manipulation and network event handling [PDF]

open access: yes, 2003
A Self-Modifiable Color Petri Net (SMCPN) which has multimedia synchronization capability and the ability to model user manipulation and network event (i.e. network congestion, etc.) handling is proposed in this paper.
Guan, SU, Liu, W, Liu, W., Guan, S.-U.
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

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