Results 81 to 90 of about 554,043 (268)
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Bulk handling of milk by the ranch to factory system
California Agriculture, 1947 Milk-holding tanks on dairy farms, used in conjunction with tank trucks, are bringing about savings to the dairyman and to the milk buyer through the elimination of the ten-gallon milk can.
E Jack, R Perry
doaj
Simulation analysis of models for estimation of empty travel time of vehicles in non-automated material handling systems [PDF]
FME Transactions, 2018 In designing or redesigning a facility like manufacturing plant or warehouse, an integral part is a proper selection of material handling system. Despite large alternatives, including automated material handling systems with conveyors or automated guided
Dukić Goran +3 more
doaj
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Research and Application of Automatic Pipe Handling System
Shiyou jixie, 2015 Domestic study on automated pipe handling system is just on starting stage.Drillpipe transfer during drilling operation is more relied on synergy of manpower and tools,which could not meet the requirement of drilling operation automation.To address this ...
Yang Lidong +3 more
doaj
The effect of hypothalamic peptides, neurohormone C and proline-rich peptide-1on the Ca2+-handling system in heartin pathophysiological conditions. [PDF]
Heliyon, 2020 Guevorkian AG.
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
FoodsPick-and-place handling of aquatic products (e.g., raw oyster) in packing processing remains manual, despite advances in soft robotic grippers as well as robotic systems that offer a path to automation in food production lines.
Yang Zhang, Zhongkui Wang
doaj +1 more source