Results 121 to 130 of about 14,920 (228)

ATP modulates holdase activity of fungal and human 110‐kilodalton heat shock proteins to promote protein folding

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Heat shock proteins of the 70‐kDa family (Hsp70s) are highly abundant and conserved molecular chaperones that help preserve proteostasis primarily by facilitating proper protein folding. Heat shock protein of the 110‐kDa family (Hsp110s), a specialized branch of the Hsp70/Hsp110 superfamily, function both as nucleotide exchange factor (NEF ...
Justin M. Kidd, Cancan Sun, Alissa Garay, Mitchell Keplinger, Colin Richter, Aaron E. May, Qinglian Liu   +6 more
wiley   +1 more source

Quality control of protein import into mammalian mitochondria

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Mitochondrial function depends on the continuous import of hundreds of nuclear‐encoded proteins. Targeting and translocation of mitochondrial proteins is a multistep process that is inherently vulnerable to defects in cytosolic quality control systems as well as perturbations in mitochondrial protein import machinery and organelle function ...
Madeleine Goldstein, Laurie Lee‐Glover, Hilla Weidberg   +2 more
wiley   +1 more source

Early versus late initiation of long‐acting insulin in paediatric and adult diabetic ketoacidosis: A systematic review and meta‐analysis of randomised control trials

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3655-3663, May 2026.
Abstract Aims Diabetic ketoacidosis (DKA) is a serious complication of diabetes, requiring intravenous (IV) insulin until resolution and subsequent transition to subcutaneous insulin. Currently, clinical guidelines vary regarding the timing of long‐acting subcutaneous insulin initiation, with some advocating early administration during IV insulin ...
Bachviet Nguyen, Stephanie Quon, Balkaran Dhaliwal, Mark Warwas, Sara Stafford   +4 more
wiley   +1 more source

Mechanistic Basis of Cholesterol Binding and Transfer in NPC2: Insights From Molecular Dynamics Simulations

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
A mechanistic basis is proposed for how variation in protein sequence perturbs cholesterol handling in Niemann–Pick type C2 (NPC2) protein. A relatively rigid hydrophobic core stabilizes cholesterol binding, a flexible but coordinated rim enables controlled access and productive transfer of cholesterol, and coordinated loop motions modulate pocket ...
Smit Patel, Nadia Elghobashi‐Meinhardt
wiley   +1 more source

The THOR network best practices for females of childbearing potential with life‐threatening hemorrhage: Guidance for emergency medical services and hospitals

Transfusion, EarlyView.
Matthew J. Levy, Holly OByrne, Eric A. Bank, Jeremy W. Cannon, Andew P. Cap, Elon Glassberg, John B. Holcomb, Donald H. Jenkins, Christine Leeper, Molly R. Sherwood, Kevin R. Ward, Mark H. Yazer, Philip C. Spinella   +12 more
wiley   +1 more source

Relay-supporting Archives: Requirements and Progress

International Journal of Digital Curation, 2009
We characterize long-term preservation of digital content as an extended relay in time, in which repeated handoffs of information occur independently at every architectural layer: at the physical layer, where bits are handed off between storage systems;
Greg Janée, James Frew, Terry Moore
doaj   +2 more sources

Redefining the role of the transfusion medicine physician in the era of advanced cellular therapies

Transfusion, EarlyView.
Eric A. Gehrie, Kevin J. Land
wiley   +1 more source

Understanding nursing handoff errors in clinical practice: trends and contributing factors based on a systematic review and meta-analysis. [PDF]

BMC Nurs
Yeom S, Kim MG, Park JH.
europepmc   +1 more source

When More May Be Better: Reconceptualizing Clinical Handoffs in Modern Medicine. [PDF]

Cureus
Berlin KE, Zhang J, Yan K, Cohen S, Yale S.   +4 more
europepmc   +1 more source

Digital Specimen Tracking- and ISO 15189-Oriented Risk Management in Anatomic Pathology: A Qualitative Study of Expert Perspectives in Western Austria. [PDF]

Diagnostics (Basel)
Sommeregger P, Pallua N, Zelger B, Kahlil R, Pallua JD.   +4 more
europepmc   +1 more source