Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa +8 more
wiley +1 more source
The Research on the Handwriting Stability in Different Devices and Conditions. [PDF]
Lai HJ, Tsai LH, Hsu KY, Yang WC.
europepmc +1 more source
Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu +6 more
wiley +1 more source
Unlocking the silent signals: Motor kinematics as a new frontier in early detection of mild cognitive impairment. [PDF]
Nagamine T.
europepmc +1 more source
IL‐2 Free Expansion of T Cells with Immunofilaments
Ratio and density of stimulatory αCD3 and αCD28 mAb on immunofilaments (IF) influence T cell expansion, cytokine production, and effector phenotype. Moreover, IL‐2 supplementation is not necessary with optimal performing IFs, which leads to simpler culture conditions, and negative side effects of IL‐2 supplementation are reduced.
Marjolein Schluck +4 more
wiley +1 more source
Measurement Tools in Occupational Therapy Practice Primary School Setting: A Scoping Review. [PDF]
Ashari P, Shiraishi M, Ishibashi Y.
europepmc +1 more source
Percutaneous prosthetic venous valves are fabricated by embedding stents in an electrospun matrix that extends luminally to form leaflets. The design shields leaflets from hyperplastic cells, isolates struts from blood contact, and avoids discrete anchoring points.
Dario Arcuti +6 more
wiley +1 more source
Sim-to-Real Domain Adaptation for Early Alzheimer's Detection from Handwriting Kinematics Using Hybrid Deep Learning. [PDF]
Bazarbekov I +4 more
europepmc +1 more source
A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra +8 more
wiley +1 more source
AI-driven approaches for dysgraphia diagnosis using online and offline handwriting data: A comprehensive scoping review. [PDF]
Fallah A, ZandiyeVakili Y, Sajedi H.
europepmc +1 more source

