Results 71 to 80 of about 35,876 (299)
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Relationship between Handwriting and Visual-Motor Integration in Primary School
Psicología Educativa: Revista de los Psicólogos de la EducaciónIntroduction: School-based literacy development involves the acquisition of complex cognitive and motor skills, among which handwriting plays a central role.
Mariana Diez, Ramón Álvarez-Vaz
doaj +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Novel geometric features for off-line writer identification
, 2016 Writer identification is an important field in forensic document examination. Typically, a writer identification system consists of two main steps: feature extraction and matching and the performance depends significantly on the feature extraction step ...
Al-Maadeed, Somaya +3 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao +6 more
wiley +1 more source
Exploring the participation of children with Down Syndrome in Handwriting Without Tears [PDF]
, 2017 Children with Down Syndrome typically experience difficulties with attention to task and lack motivation when learning to write. This article provides an evaluation of the HWT (Handwriting Without Tears) method applied as an intervention to promote ...
Eve Hutton +5 more
core +1 more source
The Comparative Influence of Culture and Schooling Environment on Handwriting Features
Arab Journal of Forensic Sciences & Forensic Medicine, 2018 Handwriting is an acquired trait of an individual which is primarily culture and environment dependent. The present study attempts to assess the relative influence of schooling environment and culture upon handwriting features.
Monika Saini, Anup K. Kapoor
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi +5 more
wiley +1 more source
Handwriting analysis for diagnosis and prognosis of Parkinson’s disease
, 2010 At present, there are no quantitative, objective methods for diagnosing the Parkinson disease. Existing methods of quantitative analysis by myograms suffer by inaccuracy and patient strain; electronic tablet analysis is limited to the visible drawing ...
Brause, Rüdiger W. +2 more
core
, 2010 The great success and high number of participants in pattern recognition related competitions last years show an important improvement of recognition and classification approaches.
Michael Blumenstein +5 more
core +1 more source