Results 51 to 60 of about 2,465,100 (294)

Emotion detection from handwriting and drawing samples using an attention-based transformer model [PDF]

open access: yesPeerJ Computer Science
Emotion detection (ED) involves the identification and understanding of an individual’s emotional state through various cues such as facial expressions, voice tones, physiological changes, and behavioral patterns.
Zohaib Ahmad Khan   +6 more
doaj   +2 more sources

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Handwriting analysis for diagnosis and prognosis of Parkinson’s disease [PDF]

open access: yes, 2010
At present, there are no quantitative, objective methods for diagnosing the Parkinson disease. Existing methods of quantitative analysis by myograms suffer by inaccuracy and patient strain; electronic tablet analysis is limited to the visible drawing ...
Brause, Rüdiger W.   +2 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Inter-relationships between objective handwriting features and executive control among children with developmental dysgraphia.

open access: yesPLoS ONE, 2018
ObjectiveTo describe handwriting and executive control features and their inter-relationships among children with developmental dysgraphia, in comparison to controls.MethodParticipants included 64 children, aged 10-12 years, 32 with dysgraphia based on ...
Sara Rosenblum
doaj   +1 more source

Texture feature column scheme for single‐ and multi‐script writer identification

open access: yesIET Biometrics, 2021
Identification of writers from images of handwriting is an interesting research problem in the handwriting recognition community. Application of image analysis and machine learning techniques to this problem allows development of computerised solutions ...
Faycel Abbas   +5 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Hybrid DL-ML Framework for Handwriting-Based Person Recognition

open access: yesNTU Journal of Engineering and Technology
This work proposes an efficient handwriting-person-based identification scheme amalgamating deep learning and regular machine learning classifiers. 6,955 fine-quality Arabic handwriting samples were gathered from 107 users.
Nabaa Alsamak, Maysaloon Abed Qasim
doaj   +1 more source

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