Results 121 to 130 of about 28,702 (214)

An Observational Study of Afatinib 30 mg Daily in Patients With Advanced Non‐Small‐Cell Lung Cancer Harboring Common EGFR Mutations Treated With Afatinib

Thoracic Cancer, Volume 17, Issue 13, July 2026.
In this prospective multicenter Phase II study, afatinib 30 mg daily demonstrated encouraging efficacy and favorable tolerability in treatment‐naive patients with advanced EGFR‐mutant NSCLC. The 6‐month progression‐free survival rate was 93.2%, objective response rate was 80.0%, and only 13.3% of patients required dose reduction, supporting a lower ...
Kenneth Sooi, Pongwut Danchaivijtr, C. K. Wong, V. D. Tu, Manavi Sachdeva, B. C. Tai, Ross A. Soo   +6 more
wiley   +1 more source

Impact of Oral Sebetralstat on Anxiety Associated With Hereditary Angioedema Attacks

Clinical &Experimental Allergy, Volume 56, Issue 7, Page 739-747, July 2026.
In the phase 3 KONFIDENT trial of oral sebetralstat for on‐demand treatment of hereditary angioedema attacks, many attacks induced moderate‐to‐extreme anxiety. Sebetralstat reduced anxiety versus placebo; time to reductions agreed with trial endpoints, such as time to beginning of symptom relief.
Timothy Craig, Emel Aygören‐Pürsün, Jonathan A. Bernstein, Paula J. Busse, Teresa Caballero, Danny M. Cohn, Mar Guilarte, Henriette Farkas, Douglas H. Jones, Sorena Kiani‐Alikhan, Michael E. Manning, Marcus Maurer, Marc A. Riedl, Sinisa Savic, H. James Wedner, Patrick F. K. Yong, Andrea Zanichelli, Sally van Kooten, Matthew Iverson, Erik Hansen, James Hao, Michael D. Smith, Christopher M. Yea, Paul K. Audhya, William R. Lumry   +24 more
wiley   +1 more source

Urban compactness and Land Use Efficiency in Indochina Capitals: A multi-method spatial assessment (2017-2024). [PDF]

PLoS One
Nguyen TT.
europepmc   +1 more source

Soil Microbial Diversity and Network Organization Respond to Land Use and Agricultural Inputs Worldwide

Global Change Biology, Volume 32, Issue 7, July 2026.
Based on a global analysis of 1921 soil samples, we show that agricultural management acts as a powerful ecological filter reshaping microbial communities. Land use and inputs—pesticides and fertilizers—drive a functional shift toward opportunistic pathogens and fragmented, less connected microbial networks, potentially compromising soil ecosystem ...
Zaki Saati‐Santamaría, Sergio Pérez‐Gorjón, Daniel Abel‐Schaad, Alberto Acedo‐Bécares, Francisca Alba‐Sánchez, Amanda Lucia Alves, Weronika Babinska‐Wensierska, Jorge Ariel Marfetán, Carolina Barroetaveña, Kara Barry, Francisco Beitia, Katerina Biniari, Elí Misael Bobadilla‐Peñaló, Gregory Bonito, Mihalis Boutaris, Victoria Bueno‐González, Guillermo Cabezas, Parharidis Charalambos, Ovidiu Copoț, Andrés de Errasti, Luis de Pedro Noriega, Philippe Delavault, Fernando Dianez‐Martínez, David Diez‐Méndez, Enrico Ercole, Abel Fernández‐Ruiz, Martina Ferraguti, Ana Laura Gallo, Paula García‐Fraile, Mario Garrido, David González del Pozo, Alina G. Greslebin, Gabriel Grilli, Edmundo Danilo Guilcapi‐Pacheco, Danny Haelewaters, Terry W. Henkel, Andrés Hirigoyen, Kentaro Hosaka, Pablo Yair Huais, Marja Jalli, Alfredo Justo, Marjo Keskitalo, Tommaso La Mantia, Aneta Lambevska, Ewald Langer, Corina Leconte, Ewa Lojkowska, David Marcos‐Vidal, Antonio J. Mendoza‐Fernández, Isabel Miralles‐Mellado, Lucía Molina, Norman Muzhinji, Minh N. Nguyen, Diego Nieto‐Lugilde, Alberto Nieto‐Palenzuela, André‐Ledoux Njouonkou, Sarah Norvell, Francisco J. Oficialdegui, Raúl Ortega Pérez, Ansa Palojärvi, Marcos Paradelo‐Pérez, Zunilda Pavone, Julio Peñas de Giles, Anna Maria Persiani, María Belén Pildain, Daniel Pinto‐Carrasco, Lucie Poulin, Jean‐Bernard Pouvreau, Paola Quatrini, David Rodríguez de la Cruz, Gonzalo M. Romano, Natalia Rosas‐Ramos, Francisca Ruano, Isabel Salcedo‐Larralde, Esteban Salmerón‐Sánchez, Katerina Sam, Cathy Sharp, Patricia Vieira Tiago, Ricardo Valenzuela, Aída M. Vasco‐Palacios, Mylonas Vasilis, María Laura Vélez, Alfredo Vizzini, Sergey Volobuev, Alan R. Wood, Pirjo Yli‐Hemminki, Nourou S. Yorou, Ivan V. Zmitrovich, Javier Bobo‐Pinilla   +88 more
wiley   +1 more source

Acute Intraoperative Disseminated Intravascular Coagulation During Suppurative Keloid Excision: A Case Report. [PDF]

Am J Case Rep
Nguyen BL, Pham MQ, Nguyen TH, Nguyen NTC, Ngo KX, Nguyen MT, Pham AQ, Vo TT, Hoang HV.   +8 more
europepmc   +1 more source

Asian Pacific Association of Gastroenterology (APAGE) Clinical Practice Guidelines on the Use of Small Molecules and IL‐23 p19 Inhibitors in Ulcerative Colitis and Crohn's Disease

Journal of Gastroenterology and Hepatology, Volume 41, Issue 7, Page 2006-2029, July 2026.
ABSTRACT Ulcerative colitis (UC) and Crohn's disease (CD) are increasingly prevalent in the Asia Pacific region, necessitating updated, region‐specific guidance on advanced therapies. Targeted small molecule agents, such as filgotinib, tofacitinib, upadacitinib, etrasimod, and ozanimod; and the IL‐23 p19 inhibitors (guselkumab, mirikizumab ...
Choon Jin Ooi, Khoon Lin Ling, Julajak Limsrivilai, Shu‐Chen Wei, Joyce Wing Yan Mak, Taku Kobayashi, Luan Minh Dang, Rupert W. Leong, Huiyu Lin, Meng‐Tzu Weng, Wan Chee Ong, Vineet Ahuja, Satimai Aniwan, Ryota Hokari, Wei Jie Jonathan Lee, Alex Hwong‐Ruey Leow, Wai‐Keung Leung, Wee‐Chian Lim, Govind Makharia, Katsuyoshi Matsuoka, Nazri Mustaffa, Siew‐Chien Ng, Mathew Philip, Pises Pisespongsa, Raja Affendi Raja Ali, Zhi Hua Ran, Marcellus Simadibrata, Jose Sollano, Malcolm Tan, Hang Dao Viet, Nik Razima Wan Ibrahim, Kai Chun Wu, Byong Duk Ye, Ida Hilmi, Asian Pacific Association of Gastroenterology (APAGE) Inflammatory Bowel Disease Committee and Asian Education Network in IBD (AEN‐IBD)   +34 more
wiley   +1 more source

Successful Whole-Lung Lavage in Anti-GM-CSF-Negative Pulmonary Alveolar Proteinosis: A Case Report. [PDF]

Am J Case Rep
Le H, Nguyen GT, Nguyen CN, Nguyen VVH, Nguyen DD, Le HM, Nguyen VAT, Chu SH, Nguyen VAT.   +8 more
europepmc   +1 more source

Association Between Frailty and Cognitive Impairment in Chronic Kidney Disease: A Systematic Review and Meta‐Analysis

Journal of Nursing Scholarship, Volume 58, Issue 4, July 2026.
ABSTRACT Background The literature has reported conflicting findings regarding the association between frailty and cognitive impairment in patients with chronic kidney disease (CKD). This systematic review and meta‐analysis examined the association between frailty and cognitive impairment in patients with CKD.
Hien Thi Bui, Renny Wulan Apriliyasari, Quyen Huong Quynh Bui, Pei‐Shan Tsai   +3 more
wiley   +1 more source

Correcting Underestimated Internal Variability Fails to Reconcile Models With Observed Pacific SST Gradient Strengthening

Geophysical Research Letters, Volume 53, Issue 12, 28 June 2026.
Abstract The equatorial Pacific zonal sea surface temperature (SST) gradient has strengthened since 1980, yet fewer than 1% of CMIP6 simulations reproduce this trend. We test whether underestimated internal variability explains this mismatch. Extreme El Niño events enhance interdecadal variability of the gradient, but CMIP6 models simulate them too ...
Yann Yvon Planton, Jérôme Vialard, Alexey Fedorov, Matthieu Lengaigne, Shayne McGregor, Malte F. Stuecker   +5 more
wiley   +1 more source

Modeling the Distribution, Impacts, and Mitigation of Anthropogenic Heat in Los Angeles

Journal of Geophysical Research: Atmospheres, Volume 131, Issue 12, 28 June 2026.
Abstract Anthropogenic heat emissions from human energy consumption contribute to the urban heat island (UHI) effect, yet their spatiotemporal distributions and impacts remain uncertain. In this study, we develop a 100 m resolution, hourly anthropogenic heat flux (AHF) data set for Los Angeles County and use the Weather Research and Forecasting model ...
Joseph Ko, Hao Hu, Yun Li, Hannah Schlaerth, Stepp Mayes, McKenna Peplinski, Andrew Jin, Dan Li, Pouya Vahmani, Kelly Sanders, George Ban‐Weiss, Jiachen Zhang   +11 more
wiley   +1 more source