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Tazobactam selects for multidrug resistance [PDF]
npj Antimicrobials and ResistancePiperacillin-Tazobactam is a β-lactam/β-lactamase inhibitor combination that is amongst the most prescribed antimicrobials in hospital medicine.
Emma R. Holden +4 more
doaj +2 more sources
Annual Review of Medicine, 1991 Laboratory investigations indicate that cancer cells can become simultaneously resistant to many different chemotherapeutic drugs that are natural products via the expression of an energy-dependent drug efflux pump. This multidrug transporter is a plasma membrane glycoprotein encoded in the human by the MDR1 gene.
I, Pastan, M M, Gottesman
+9 more sources
Multidrug-resistant tuberculosis [PDF]
The Lancet, 2019 The ideal number of drugs needed and treatment duration are crucial issues in the management of multidrug-resistant tuberculosis (MDR-TB). Thus, we read with interest the Article by the Collaborative Group for the Meta-Analysis of Individual Patient Data in MDR-TB treatment–2017,1 the results of which support our proposal,2 from 2015, to classify anti ...
Bern-Thomas, Nyang'wa +3 more
+10 more sources
Multidrug resistance associated proteins in multidrug resistance [PDF]
Chinese Journal of Cancer, 2012 Multidrug resistance proteins (MRPs) are members of the C family of a group of proteins named ATP-binding cassette (ABC) transporters. These ABC transporters together form the largest branch of proteins within the human body. The MRP family comprises of 13 members, of which MRP1 to MRP9 are the major transporters indicated to cause multidrug resistance
Sodani, Kamlesh +3 more
openaire +2 more sources
Tropical Animal Science Journal, 2021 This study was aimed to find out that broiler chicken farms have problems with antibiotic resistance Citrobacter freundii and determined the prevalence and class 1 integron encoding gene.
A. M. Witaningrum +3 more
doaj +1 more source
Multidrug resistant tuberculosis [PDF]
BMJ, 2015 #### The bottom line Tuberculosis remains a major cause of morbidity and mortality globally, with an estimated nine million people developing the disease and 1.5 million deaths in 2013; equating to 4100 deaths a day.1 Nevertheless, considerable gains have been made in international tuberculosis control; incidence rates are decreasing (albeit slowly ...
Millard, James +2 more
openaire +2 more sources
In vivo selection of resistant E. coli after ingestion of milk with added drug residues. [PDF]
, 2014 Antimicrobial resistance represents a major global threat to modern medicine. In vitro studies have shown that very low concentrations of drugs, as frequently identified in the environment, and in foods and water for human and animal consumption, can ...
Bicalho, Rodrigo Carvalho +3 more
core +10 more sources
The Impact of Triclosan on the Spread of Antibiotic Resistance in the Environment [PDF]
, 2015 Triclosan (TCS) is a commonly used antimicrobial agent that enters wastewater treatment plants (WWTPs) and the environment. An estimated 1.1 × 105 to 4.2 × 105 kg of TCS are discharged from these WWTPs per year in the United States.
Carey, Daniel E., McNamara, Patrick J.
core +3 more sources
Informatics in Medicine Unlocked, 2021 Development of multidrug resistance is the main obstacle for treating infections of Pseudomonas aeruginosa, an opportunistic pathogen responsible for a wide range of persistent infections throughout the body.
Nazanin Hosseinkhan +2 more
doaj +1 more source
Risk of acquired drug resistance during short-course directly observed treatment of tuberculosis in an area with high levels of drug resistance. [PDF]
, 2007 BACKGROUND: Data on the performance of standardized short-course directly observed treatment (DOTS) of tuberculosis (TB) in areas with high levels of drug resistance and on the potential impact of DOTS on amplification of resistance are limited ...
Cox +33 more
core +2 more sources