Results 21 to 30 of about 234,319 (307)

The Effects and Mechanisms of Periplaneta americana Extract Reversal of Multi-Drug Resistance in BEL-7402/5-FU Cells

Molecules, 2016
The present study reports the reversing effects of extracts from P. americana on multidrug resistance of BEL-7402/5-FU cells, as well as a preliminary investigation on their mechanism of action.
Falu Yuan, Junyong Liu, Tingting Qiao, Ting Li, Qi Shen, Fang Peng   +5 more
doaj   +1 more source

Multidrug-Resistant Tuberculosis

Chest, 2006
Multidrug-resistant tuberculosis (MDR-TB) caused by Mycobacterium tuberculosis resistant to both isoniazid and rifampicin with or without resistance to other drugs is among the most worrisome elements of the pandemic of antibiotic resistance. Globally, about three per cent of all newly diagnosed patients have MDR-TB.
S K, Sharma, A, Mohan
openaire   +2 more sources

Antimicrobial Resistance: Two-Component Regulatory Systems and Multidrug Efflux Pumps

Antibiotics, 2023
The number of multidrug-resistant bacteria is rapidly spreading worldwide. Among the various mechanisms determining resistance to antimicrobial agents, multidrug efflux pumps play a noteworthy role because they export extraneous and noxious substrates ...
Giuseppe Valerio De Gaetano, Germana Lentini, Agata Famà, Francesco Coppolino, Concetta Beninati   +4 more
doaj   +1 more source

A light in multidrug resistance: Photodynamic treatment of multidrug-resistant tumors

Journal of Biomedical Science, 2003
The major drawback of cancer chemotherapy is the development of multidrug-resistant (MDR) tumor cells, which are cross-resistant to a broad range of structurally and functionally unrelated agents, making it difficult to treat these tumors. In the last decade, a number of authors have studied the effects of photodynamic therapy (PDT), a combination of ...
Márcia Alves Marques, Capella, Luiz Sabbatini, Capella   +1 more
openaire   +2 more sources

Programmatically selected multidrug-resistant strains drive the emergence of extensively drug-resistant tuberculosis in South Africa [PDF]

, 2013
South Africa shows one of the highest global burdens of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB). Since 2002, MDR-TB in South Africa has been treated by a standardized combination therapy, which until 2010 included
Pillay, Manormoney, van Helden, Paul D., Nicolaas C. Gey van Pittius (173264), Paul D. van Helden (33594), Marlein E Bosman, Gagneux, Sebastien, Thomas C Victor, Manormoney Pillay (257769), Nicolaas C Gey van Pittius, Borna Müller (173253), Hayes, Cindy, Streicher, Elizabeth M., Andre Trollip (449922), Robin M Warren, Elizabeth M Streicher, Trollip, Andre, Violet N. Chihota (143307), Warren, Robin M., Bosman, Marlein E., Müller, Borna, Violet N Chihota, Cindy Hayes, Marisa Klopper (398815), Cindy Hayes (449923), Elizabeth M. Streicher (439727), Borna Müller, Paul D van Helden, Marlein E. Bosman (449924), Klopper, Marisa, Gerrit Coetzee, Sebastien Gagneux (149824), Chihota, Violet N., Andre Trollip, Marisa Klopper, Sebastien Gagneux, Gerrit Coetzee (296078), Victor, Thomas C., Manormoney Pillay, Coetzee, Gerrit, Gey van Pittius, Nicolaas C., Robin M. Warren (33593), Thomas C. Victor (185348)   +41 more
core   +1 more source

Antimicrobial-drug Susceptibility of Human and Animal Salmonella Typhimurium, Minnesota, 1997–2003

Emerging Infectious Diseases, 2005
We compared antimicrobial resistance phenotypes and pulsed-field gel electrophoresis (PFGE) subtypes of 1,028 human and 716 animal Salmonella enterica serotype Typhimurium isolates from Minnesota from 1997 to 2003.
Stephanie D. Wedel, Jeffrey B. Bender, Fe T. Leano, David J. Boxrud, Craig Hedberg, Kirk E. Smith   +5 more
doaj   +1 more source

Diagnosis and Interim Treatment Outcomes from the First Cohort of Multidrug-Resistant Tuberculosis Patients in Tanzania. [PDF]

, 2013
Kibong'oto National Tuberculosis Hospital (KNTH), Kilimanjaro, Tanzania. Characterize the diagnostic process and interim treatment outcomes from patients treated for multidrug-resistant tuberculosis (MDR-TB) in Tanzania.
Kumburu Happiness H., Ndusilo, N.D., Boeree, M.J., Kibiki, Gibson S, Mpagama Stellah G., Kumburu, Happiness H, Houpt, Eric R, Heysell, Scott K, Eric R Houpt, Boeree Martin J., Kisonga, Riziki M, Kibiki, G.S., Nora D Ndusilo, Jean Gratz, Ndusilo Nora D., Riziki M Kisonga, Boeree, Martin J, Lekule Isack A., Stellah G Mpagama, Martin J Boeree, Heysell, S.K., Kisonga Riziki M., Mpagama, Stellah G, Ndusilo, Nora D, Kumburu, H.H., Scott K Heysell, Lekule, Isack A, Gratz, J., Kisonga, R.M., Gratz, Jean, Kibiki Gibson S., Houpt, E.R., Gibson S Kibiki, Heysell Scott K., Mpagama, S.G., Lekule, I.A., Houpt Eric R., Isack A Lekule, Gratz Jean, Happiness H Kumburu   +39 more
core   +1 more source

Prolonged carriage of OXA-244-carbapenemase-producing Escherichia coli complicates epidemiological investigations

International Journal of Medical Microbiology
The rapid increase of OXA-244-producing Escherichia coli, predominantly driven by genetically clustered isolates of sequence type (ST)38, has been observed in at least nine European countries, including Germany. However, the reasons for the spread of OXA-
Felix Reichert, Simon Brinkwirth, Niels Pfennigwerth, Sebastian Haller, Lena Sophie Fritsch, Tim Eckmanns, Guido Werner, Sören Gatermann, Jörg B. Hans   +8 more
doaj   +1 more source

An open-source nanopore-only sequencing workflow for analysis of clonal outbreaks delivers short-read level accuracy

Journal of Clinical Microbiology
In this work, we present an optimized nanopore long-read only sequencing workflow for epidemiologic analysis of clonal outbreaks built with open-source tools.
Nick Vereecke, Thomas B. Yoon, Ting L. Luo, Brendan W. Corey, Francois Lebreton, Patrick T. Mc Gann, John P. Dekker   +6 more
doaj   +1 more source

Autophagy and Transporter-Based Multi-Drug Resistance

Cells, 2012
All the therapeutic strategies for treating cancers aim at killing the cancer cells via apoptosis (programmed cell death type I). Defective apoptosis endow tumor cells with survival. The cell can respond to such defects with autophagy.
Zhe-Sheng Chen, Kurt Degenhardt, Dong-Mei Zhang, Priyank Kumar   +3 more
doaj   +1 more source