Results 31 to 40 of about 235,517 (308)

Prolonged carriage of OXA-244-carbapenemase-producing Escherichia coli complicates epidemiological investigations

International Journal of Medical Microbiology
The rapid increase of OXA-244-producing Escherichia coli, predominantly driven by genetically clustered isolates of sequence type (ST)38, has been observed in at least nine European countries, including Germany. However, the reasons for the spread of OXA-
Felix Reichert, Simon Brinkwirth, Niels Pfennigwerth, Sebastian Haller, Lena Sophie Fritsch, Tim Eckmanns, Guido Werner, Sören Gatermann, Jörg B. Hans   +8 more
doaj   +1 more source

Antimicrobial-drug Susceptibility of Human and Animal Salmonella Typhimurium, Minnesota, 1997–2003

Emerging Infectious Diseases, 2005
We compared antimicrobial resistance phenotypes and pulsed-field gel electrophoresis (PFGE) subtypes of 1,028 human and 716 animal Salmonella enterica serotype Typhimurium isolates from Minnesota from 1997 to 2003.
Stephanie D. Wedel, Jeffrey B. Bender, Fe T. Leano, David J. Boxrud, Craig Hedberg, Kirk E. Smith   +5 more
doaj   +1 more source

Natural Products with Activity against Multidrug-Resistant Tumor Cells [PDF]

, 2013
Multidrug resistance is the main mechanism by which cancers develop resistance to chemotherapeutic drugs. Consequently, it is also an important factor in the failure of many forms of chemotherapy.
Camila Bernardes de Andrade Carli, Quilles, Marcela Bassi [UNESP], Marcela Bassi Quilles, Iracilda Zeppone Carlos, Bernardes de Andrade Carli, Camila [UNESP], Carlos, Iracilda Zeppone [UNESP]   +5 more
core   +1 more source

An open-source nanopore-only sequencing workflow for analysis of clonal outbreaks delivers short-read level accuracy

Journal of Clinical Microbiology
In this work, we present an optimized nanopore long-read only sequencing workflow for epidemiologic analysis of clonal outbreaks built with open-source tools.
Nick Vereecke, Thomas B. Yoon, Ting L. Luo, Brendan W. Corey, Francois Lebreton, Patrick T. Mc Gann, John P. Dekker   +6 more
doaj   +1 more source

Autophagy and Transporter-Based Multi-Drug Resistance

Cells, 2012
All the therapeutic strategies for treating cancers aim at killing the cancer cells via apoptosis (programmed cell death type I). Defective apoptosis endow tumor cells with survival. The cell can respond to such defects with autophagy.
Zhe-Sheng Chen, Kurt Degenhardt, Dong-Mei Zhang, Priyank Kumar   +3 more
doaj   +1 more source

Activating alternative transport modes in a multidrug resistance efflux pump to confer chemical susceptibility

Nature Communications, 2022
Antibiotic resistance through multidrug efflux is a major hurdle in antibiotic development. Here, authors experimentally demonstrate that EmrE, a small multidrug resistance efflux pump from E.
Peyton J. Spreacker, Nathan E. Thomas, Will F. Beeninga, Merissa Brousseau, Colin J. Porter, Kylie M. Hibbs, Katherine A. Henzler-Wildman   +6 more
doaj   +1 more source

The prevalences of Salmonella Genomic Island 1 variants in human and animal Salmonella Typhimurium DT104 are distinguishable using a Bayesian approach [PDF]

, 2011
Throughout the 1990s, there was an epidemic of multidrug resistant Salmonella Typhimurium DT104 in both animals and humans in Scotland. The use of antimicrobials in agriculture is often cited as a major source of antimicrobial resistance in pathogenic ...
Matthew J Denwood, Reid, S W J, Derek J Brown, Daniel T Haydon, Mellor Dominic J., Mellor, D J, Louise Matthews, Alison E. Mather, Matthews, L., Reid Stuart W. J., Mather, A E, Haydon, D T, Derek J. Brown, Alison E Mather, John E Coia, Coia John E., Matthews, L, Mather, A.E., Stuart W J Reid, Daniel T. Haydon, Brown, D J, Denwood Matthew J., Haydon, D.T., Coia, J E, Dominic J. Mellor, Brown Derek J., John E. Coia, Coia, J.E., Reid, S.W.J., Matthew J. Denwood, Matthews Louise, Stuart W. J. Reid, Denwood, M.J., Denwood, M J, Mather Alison E., Mellor, D.J., Dominic J Mellor, Haydon Daniel T., Brown, D.J.   +38 more
core   +1 more source

Antimicrobial Resistance Surveillance: Data Harmonisation and Data Selection within Secondary Data Use

Antibiotics
Resistance to last-resort antibiotics is a global threat to public health. Therefore, surveillance and monitoring systems for antimicrobial resistance should be established on a national and international scale.
Sinja Bleischwitz, Tristan Salomon Winkelmann, Yvonne Pfeifer, Martin Alexander Fischer, Niels Pfennigwerth, Jens André Hammerl, Ulrike Binsker, Jörg B. Hans, Sören Gatermann, Annemarie Käsbohrer, Guido Werner, Lothar Kreienbrock   +11 more
doaj   +1 more source

Detection approaches for multidrug resistance genes of leukemia [PDF]

, 2017
Ying Du, Baoan Chen Department of Hematology and Oncology (Key Department of Jiangsu Medicine), School of Medicine, Zhongda Hospital, Southeast University, Nanjing, Jiangsu Province, People’s Republic of China Abstract: Leukemia is a clonal ...
Baoan Chen, Du Y, Ying Du, Chen B
core   +2 more sources

Multidrug Resistance in Fungi: Regulation of Transporter-encoding Gene Expression

Frontiers in Physiology, 2014
A critical risk to the continued success of antifungal chemotherapy is the acquisition of resistance; a risk exacerbated by the few classes of effective antifungal drugs.
Sanjoy ePaul, Scott eMoye-Rowley
doaj   +1 more source