Results 31 to 40 of about 2,406,837 (296)

Investigation of the role of LRP in multidrug resistance [PDF]

, 1998
There have been many reports linking the overexpression of the lung resistance-related protein (LRP) with cross-resistance to chemotherapeutic drugs.
Byrne, Daragh
core   +2 more sources

The Effects and Mechanisms of Periplaneta americana Extract Reversal of Multi-Drug Resistance in BEL-7402/5-FU Cells

Molecules, 2016
The present study reports the reversing effects of extracts from P. americana on multidrug resistance of BEL-7402/5-FU cells, as well as a preliminary investigation on their mechanism of action.
Falu Yuan, Junyong Liu, Tingting Qiao, Ting Li, Qi Shen, Fang Peng   +5 more
doaj   +1 more source

Antimicrobial Resistance: Two-Component Regulatory Systems and Multidrug Efflux Pumps

Antibiotics, 2023
The number of multidrug-resistant bacteria is rapidly spreading worldwide. Among the various mechanisms determining resistance to antimicrobial agents, multidrug efflux pumps play a noteworthy role because they export extraneous and noxious substrates ...
Giuseppe Valerio De Gaetano, Germana Lentini, Agata Famà, Francesco Coppolino, Concetta Beninati   +4 more
doaj   +1 more source

Antimicrobial resistance and virulence determinants in European Salmonella genomic island 1-positive Salmonella enterica isolates from different origins. [PDF]

, 2011
Salmonella genomic island 1 (SGI1) contains a multidrug resistance region conferring the ampicillin-chloramphenicol-streptomycin-sulfamethoxazole-tetracycline resistance phenotype encoded by bla(PSE-1), floR, aadA2, sul1, and tet(G).
Hauser, E., Dep Infectieziekten Immunologie, Advances in Veterinary Medicine, Beutlich, Janine, Rodicio, M. R., Schroeter, A., Threlfall, J., Med-Vet-Net WP21 Project Group, Janine Beutlich, Bernd Appel, Malorny, B., Trelfall, J., Andreas Schroeter, Malorny, Burkhard, Thelfall, J., Helmuth, R., Jahn, S., Burkhard Malorny, Elisabeth Hauser, Reiner Helmuth, Stephan Hühn, Dik Mevius, Beatriz Guerra, Mevius, D.J., Rodicio, M.R., Maria Rosario Rodicio, Jahn, Silke, John Threlfall, Appel, B., Rodicio Rodicio, María del Rosario, Silke Jahn, Hühn, S., Mevius, D., Beutlich, J., Rosario Rodicio, M., Guerra, B.   +35 more
core   +2 more sources

Topical colchicine selection of keratinocytes transduced with the multidrug resistance gene (MDR1) can sustain and enhance transgene expression in vivo [PDF]

, 2004
In gene therapy, a clinically relevant therapeutic effect requires long-term expression of the desired gene at a level sufficient to correct or at least alleviate the underlying gene defect.
Pfützner, Wolfgang, Vogel, Jonathan C.
core   +2 more sources

Fungicide-driven evolution and molecular basis of multidrug resistance in field populations of the grey mould fungus Botrytis cinerea [PDF]

, 2009
The grey mould fungus Botrytis cinerea causes losses of commercially important fruits, vegetables and ornamentals worldwide. Fungicide treatments are effective for disease control, but bear the risk of resistance development.
Pradier Jean-Marc, Pradier, J.M., Walker, Anne-Sophie, Mernke, Dennis, Pradier, Jean Marc, J. M., Leroux, Pierre, Matthias Hahn, Matthias Kretschmer, Sabine Fillinger, Walker, Anne Sophie, Kretschmer, M., Hahn, Matthias, Fillinger Sabine, Jean-Marc Pradier, Mosbach, Andreas, Walker, A.S., Mernke, Denis, Kretschmer Matthias, Mernke, D., Fillinger, S., de Waard, Maarten A, Maarten A De Waard, Walker, Anne Sophie, A. S., Leroux, P., de Waard, M.A., De Waard Maarten A., Leroux Pierre, Fillinger-David, Sabine, Helma, S. H., Anne-Sophie Walker, Pierre Leroux, Waard, Maarten A. De, Schoonbeek, Henk-jan, Leroch, Michaela, Leroch, M., Pradier, Jean Marc, Leroux, Pierre, P., Mosbach, A., Waard, M.A., de, Dennis Mernke, Pradier, Jean-Marc, Hahn Matthias, Leroch Michaela, Walker Anne-Sophie, Schoonbeek Henk-Jan, Fillinger-David, Sabine, Helma, Henk-Jan Schoonbeek, Mernke Dennis, Fillinger, Sabine, Mosbach Andreas, Andreas Mosbach, Michaela Leroch, Kretschmer, Matthias, Schoonbeek, H.J., Hahn, M.   +53 more
core   +1 more source

Antimicrobial-drug Susceptibility of Human and Animal Salmonella Typhimurium, Minnesota, 1997–2003

Emerging Infectious Diseases, 2005
We compared antimicrobial resistance phenotypes and pulsed-field gel electrophoresis (PFGE) subtypes of 1,028 human and 716 animal Salmonella enterica serotype Typhimurium isolates from Minnesota from 1997 to 2003.
Stephanie D. Wedel, Jeffrey B. Bender, Fe T. Leano, David J. Boxrud, Craig Hedberg, Kirk E. Smith   +5 more
doaj   +1 more source

Multidrug-Resistant Tuberculosis

Chest, 2006
Multidrug-resistant tuberculosis (MDR-TB) caused by Mycobacterium tuberculosis resistant to both isoniazid and rifampicin with or without resistance to other drugs is among the most worrisome elements of the pandemic of antibiotic resistance. Globally, about three per cent of all newly diagnosed patients have MDR-TB.
S K, Sharma, A, Mohan
openaire   +2 more sources

Programmatically selected multidrug-resistant strains drive the emergence of extensively drug-resistant tuberculosis in South Africa [PDF]

, 2013
South Africa shows one of the highest global burdens of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB). Since 2002, MDR-TB in South Africa has been treated by a standardized combination therapy, which until 2010 included
Pillay, Manormoney, van Helden, Paul D., Nicolaas C. Gey van Pittius (173264), Paul D. van Helden (33594), Marlein E Bosman, Gagneux, Sebastien, Thomas C Victor, Manormoney Pillay (257769), Nicolaas C Gey van Pittius, Borna Müller (173253), Hayes, Cindy, Streicher, Elizabeth M., Andre Trollip (449922), Robin M Warren, Elizabeth M Streicher, Trollip, Andre, Violet N. Chihota (143307), Warren, Robin M., Bosman, Marlein E., Müller, Borna, Violet N Chihota, Cindy Hayes, Marisa Klopper (398815), Cindy Hayes (449923), Elizabeth M. Streicher (439727), Borna Müller, Paul D van Helden, Marlein E. Bosman (449924), Klopper, Marisa, Gerrit Coetzee, Sebastien Gagneux (149824), Chihota, Violet N., Andre Trollip, Marisa Klopper, Sebastien Gagneux, Gerrit Coetzee (296078), Victor, Thomas C., Manormoney Pillay, Coetzee, Gerrit, Gey van Pittius, Nicolaas C., Robin M. Warren (33593), Thomas C. Victor (185348)   +41 more
core   +2 more sources

Prolonged carriage of OXA-244-carbapenemase-producing Escherichia coli complicates epidemiological investigations

International Journal of Medical Microbiology
The rapid increase of OXA-244-producing Escherichia coli, predominantly driven by genetically clustered isolates of sequence type (ST)38, has been observed in at least nine European countries, including Germany. However, the reasons for the spread of OXA-
Felix Reichert, Simon Brinkwirth, Niels Pfennigwerth, Sebastian Haller, Lena Sophie Fritsch, Tim Eckmanns, Guido Werner, Sören Gatermann, Jörg B. Hans   +8 more
doaj   +1 more source