Results 31 to 40 of about 349,410 (289)

Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic [PDF]

, 2006
We investigated multidrug-resistant (MDR) Mycobacterium tuberculosis strains in Bangui, Central African Republic. We found 39.6% with the same spoligotype and synonymous single nucleotide polymorphism in the mutT1 gene.
Nouvel, Laurent-Xavier, Kassa-Kelembho, Eric, Dos Vultos, Tiago, Zandanga, Germain, Rauzier, Jean, Lafoz, Carmen, Martin, Carlos, Blazquez, Jesus, Talarmin, Antoine, Gicquel, Brigitte   +9 more
core   +2 more sources

Impact of amoxicillin-clavulanate followed by autologous fecal microbiota transplantation on fecal microbiome structure and metabolic potential [PDF]

, 2018
The spread of multidrug resistance among pathogenic organisms threatens the efficacy of antimicrobial treatment options. The human gut serves as a reservoir for many drug-resistant organisms and their resistance genes, and perturbation of the gut ...
Bulow, Christopher, Burnham, Carey-Ann D, CDC Prevention Epicenter Program,, Dantas, Gautam, Dubberke, Erik R, Hink, Tiffany, Jones, Susan, Kwon, Jennie H, Langdon, Amy, Patel, Sanket, Reske, Kimberly A, Seiler, Sondra, Sun, Xiaoqing, Wallace, Meghan   +13 more
core   +2 more sources

Multidrug-resistant Tuberculosis

Medical Clinics of North America, 2013
Multidrug-resistant tuberculosis (MDR-TB) threatens to become the dominant form of tuberculosis in many parts of the world because of decades of inappropriate treatment on a global scale. Infection with MDR-TB is associated with poor outcomes because of delays in treatment and the need for complex, toxic, and long medication regimens.
Lemos, Antônio Carlos Moreira, Matos, Eliana Dias   +1 more
openaire   +9 more sources

Prolonged carriage of OXA-244-carbapenemase-producing Escherichia coli complicates epidemiological investigations

International Journal of Medical Microbiology
The rapid increase of OXA-244-producing Escherichia coli, predominantly driven by genetically clustered isolates of sequence type (ST)38, has been observed in at least nine European countries, including Germany. However, the reasons for the spread of OXA-
Felix Reichert, Simon Brinkwirth, Niels Pfennigwerth, Sebastian Haller, Lena Sophie Fritsch, Tim Eckmanns, Guido Werner, Sören Gatermann, Jörg B. Hans   +8 more
doaj   +1 more source

Antimicrobial-drug Susceptibility of Human and Animal Salmonella Typhimurium, Minnesota, 1997–2003

Emerging Infectious Diseases, 2005
We compared antimicrobial resistance phenotypes and pulsed-field gel electrophoresis (PFGE) subtypes of 1,028 human and 716 animal Salmonella enterica serotype Typhimurium isolates from Minnesota from 1997 to 2003.
Stephanie D. Wedel, Jeffrey B. Bender, Fe T. Leano, David J. Boxrud, Craig Hedberg, Kirk E. Smith   +5 more
doaj   +1 more source

Detecting Mutations in the Mycobacterium tuberculosis Pyrazinamidase Gene pncA to Improve Infection Control and Decrease Drug Resistance Rates in Human Immunodeficiency Virus Coinfection. [PDF]

, 2016
Hospital infection control measures are crucial to tuberculosis (TB) control strategies within settings caring for human immunodeficiency virus (HIV)-positive patients, as these patients are at heightened risk of developing TB.
Bangsberg, Butler, Campos, Carlton A. Evans, Caviedes, Daniela E. Kirwan, David A. J. Moore, Dooley, Eduardo Ticona, Escombe, Escombe, Evans, Franzblau, Hannan, Hu, Huang, Iwamoto, Jon S. Friedland, Jorge Coronel, Kawai, Lilia Z. Cabrera, Louis Grandjean, Luz Caviedes, Luz Huaroto, Matthew Z. Dudley, Mirko Zimic, Mitchison, Moore, Moore, Patricia Sheen, Raviglione, Richard Rodriguez, Robert H. Gilman, Scorpio, Sheen, Sheen, Sheen, Steele, Stricof, Víctor Chávez-Pérez, Wells, Willingham   +41 more
core   +2 more sources

An open-source nanopore-only sequencing workflow for analysis of clonal outbreaks delivers short-read level accuracy

Journal of Clinical Microbiology
In this work, we present an optimized nanopore long-read only sequencing workflow for epidemiologic analysis of clonal outbreaks built with open-source tools.
Nick Vereecke, Thomas B. Yoon, Ting L. Luo, Brendan W. Corey, Francois Lebreton, Patrick T. Mc Gann, John P. Dekker   +6 more
doaj   +1 more source

Autophagy and Transporter-Based Multi-Drug Resistance

Cells, 2012
All the therapeutic strategies for treating cancers aim at killing the cancer cells via apoptosis (programmed cell death type I). Defective apoptosis endow tumor cells with survival. The cell can respond to such defects with autophagy.
Zhe-Sheng Chen, Kurt Degenhardt, Dong-Mei Zhang, Priyank Kumar   +3 more
doaj   +1 more source

Antimicrobial Resistance Surveillance: Data Harmonisation and Data Selection within Secondary Data Use

Antibiotics
Resistance to last-resort antibiotics is a global threat to public health. Therefore, surveillance and monitoring systems for antimicrobial resistance should be established on a national and international scale.
Sinja Bleischwitz, Tristan Salomon Winkelmann, Yvonne Pfeifer, Martin Alexander Fischer, Niels Pfennigwerth, Jens André Hammerl, Ulrike Binsker, Jörg B. Hans, Sören Gatermann, Annemarie Käsbohrer, Guido Werner, Lothar Kreienbrock   +11 more
doaj   +1 more source

Activating alternative transport modes in a multidrug resistance efflux pump to confer chemical susceptibility

Nature Communications, 2022
Antibiotic resistance through multidrug efflux is a major hurdle in antibiotic development. Here, authors experimentally demonstrate that EmrE, a small multidrug resistance efflux pump from E.
Peyton J. Spreacker, Nathan E. Thomas, Will F. Beeninga, Merissa Brousseau, Colin J. Porter, Kylie M. Hibbs, Katherine A. Henzler-Wildman   +6 more
doaj   +1 more source