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Multidrug-resistant tuberculosis [PDF]
BMC Infectious Diseases, 2008 With almost 9 million new cases each year, tuberculosis remains one of the most feared diseases on the planet. Led by the STOP-TB Partnership and WHO, recent efforts to combat the disease have made considerable progress in a number of countries. However, the emergence of mutated strains of Mycobacterium tuberculosis that are resistant to the major anti-
McNerney Ruth, Zager Ellen M
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Critical roles of Hedgehog signaling pathway in regulating the multidrug resistance of ovarian cancer [PDF]
Journal of Ovarian ResearchOvarian cancer (OC) is a life-threatening disease with high morbidity and mortality rates among women. Treatment inevitably requires the use of multiple drugs, including platinum-based agents, taxanes, and targeted therapies, across all stages and ...
Ruixue Bi +9 more
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Infection and Drug Resistance, 2019 Heba Shehta Said, Eman Salama Abdelmegeed Department of Microbiology and Immunology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt Introduction: Enterococci commonly inhabit the gastrointestinal tract of both human and animals; however,
Said HS, Abdelmegeed ES
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Annals of Medicine, 1991 Resistance of malignant cells to cytotoxic agents is often a limiting factor to successful chemotherapy. The classical multidrug resistance is characterised by overexpression of a membrane protein, P-glycoprotein, which acts like a drug extruding pump reducing accumulation of cytotoxic agents inside malignant cells, thereby preventing their function ...
M I, Tiirikainen, T, Krusius
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Multidrug resistance associated proteins in multidrug resistance [PDF]
Chinese Journal of Cancer, 2012 Multidrug resistance proteins (MRPs) are members of the C family of a group of proteins named ATP-binding cassette (ABC) transporters. These ABC transporters together form the largest branch of proteins within the human body. The MRP family comprises of 13 members, of which MRP1 to MRP9 are the major transporters indicated to cause multidrug resistance
Sodani, Kamlesh +3 more
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Tropical Animal Science Journal, 2021 This study was aimed to find out that broiler chicken farms have problems with antibiotic resistance Citrobacter freundii and determined the prevalence and class 1 integron encoding gene.
A. M. Witaningrum +3 more
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Multidrug-resistant tuberculosis [PDF]
The Lancet, 2019 The ideal number of drugs needed and treatment duration are crucial issues in the management of multidrug-resistant tuberculosis (MDR-TB). Thus, we read with interest the Article by the Collaborative Group for the Meta-Analysis of Individual Patient Data in MDR-TB treatment–2017,1 the results of which support our proposal,2 from 2015, to classify anti ...
Caminero, José A . +2 more
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Canadian Journal of Infectious Diseases and Medical Microbiology, 2020 Objective. This study aimed to detect 5 kinds of genes related to plasmid-mediated quinolone resistance in four species of nonfermenting bacteria with 2 drug resistance phenotypes (multidrug resistance and pandrug resistance), which were Acinetobacter ...
De-Song Ming +2 more
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Informatics in Medicine Unlocked, 2021 Development of multidrug resistance is the main obstacle for treating infections of Pseudomonas aeruginosa, an opportunistic pathogen responsible for a wide range of persistent infections throughout the body.
Nazanin Hosseinkhan +2 more
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Microbiology Spectrum, 2022 The spread of resistance genes via horizontal plasmid transfer plays a significant role in the formation of multidrug-resistant (MDR) Pseudomonas aeruginosa strains. Here, we identified a megaplasmid (ca.
Meng Li +6 more
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