Results 91 to 100 of about 1,691,113 (258)

Pre-Clinical Studies of Inactivated Polivalent Vaccine Against Hemorrhagic Fever with Renal Syndrome

open access: yesЭпидемиология и вакцинопрофилактика, 2019
Relevance. Hemorrhagic fever with renal syndrome (HFRS) is a non-transmissible viral zoonosis widespread in Eurasia, and in Russia it occupies a leading position among zoonotic viral infections and one of the first places among all natural focal human ...
A. A. Sinyugina   +7 more
doaj   +1 more source

neutrophils are on the payroll [PDF]

open access: yes, 2015
Viral hemorrhagic fever caused by hantaviruses is an emerging infectious disease for which suitable treatments are not available. In order to improve this situation a better understanding of hantaviral pathogenesis is urgently required.
Krüger, Detlev H.   +2 more
core   +1 more source

Innate Immunity Never “NODs” Off: NLRs Regulate the Host Anti‐Viral Immune Response

open access: yesImmunological Reviews, Volume 330, Issue 1, March 2025.
ABSTRACT A robust innate immune response is essential in combating viral pathogens. However, it is equally critical to quell overzealous immune signaling to limit collateral damage and enable inflammation resolution. Pattern recognition receptors are critical regulators of these processes.
Mackenzie K. Woolls   +5 more
wiley   +1 more source

In-Cell Western Assays to Evaluate Hantaan Virus Replication as a Novel Approach to Screen Antiviral Molecules and Detect Neutralizing Antibody Titers

open access: yesFrontiers in Cellular and Infection Microbiology, 2017
Hantaviruses encompass rodent-borne zoonotic pathogens that cause severe hemorrhagic fever disease with high mortality rates in humans. Detection of infectious virus titer lays a solid foundation for virology and immunology researches.
Hong-Wei Ma   +10 more
doaj   +1 more source

Evaluation and validation on cellular immunoreactivity of Hantaan virus Gc

open access: yes陆军军医大学学报, 2023
Objective To screen, identify and verify the immunoreactive epitopes on Hantaan virus glycoprotein C-terminal (HTNV Gc). Methods On the basis of predicting the major histocompatibility complex (MHC) gene in more than 98% of the global population, the ...
XIE Mingyang   +4 more
doaj   +1 more source

Wildlife Pathogens and Zoonotic Disease Risk Assessment in Vietnam: A Wildlife Trade Hotspot

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Vietnam is a wildlife trade hotspot presenting multiple high‐risk interfaces for pathogen spillover from wildlife to humans. However, the zoonotic disease risk remains poorly characterized in the country and needs to be assessed to better inform policy dialog and legislative reforms.
Alice Latinne   +2 more
wiley   +1 more source

Evaluation of a Luminex‐Based Multiplex Immunoassay of Hemorrhagic Fever Viruses in Senegal

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Given the growing threat posed by viral hemorrhagic fevers, the development of surveillance tools is crucial to provide accurate and rapid solutions. Public health response involves risk assessment as well as effective and sustainable surveillance to ensure downstream communication and preparedness. A serological approach that offers high precision and
Safietou Sankhe   +17 more
wiley   +1 more source

Multiplex PCR-Based Nanopore Sequencing and Epidemiological Surveillance of Hantaan orthohantavirus in Apodemus agrarius, Republic of Korea

open access: yesViruses, 2021
Whole-genome sequencing of infectious agents enables the identification and characterization of emerging viruses. The MinION device is a portable sequencer that allows real-time sequencing in fields or hospitals.
Kyungmin Park   +15 more
doaj   +1 more source

Cell Fusion Activities of Hantaan Virus Envelope Glycoproteins [PDF]

open access: greenJournal of Virology, 2004
ABSTRACT Hantaan virus (HTNV)-infected Vero E6 cells undergo cell fusion with both infected and uninfected cells under low-pH conditions. Flow cytometry and fluorescence microscopy of HTNV-infected Vero E6 cells showed that envelope glycoproteins (GPs) were located both on the cell surface and in the cytoplasm.
Michiko Ogino   +6 more
openalex   +3 more sources

Metatranscriptomic Analysis Uncovers RNA Virus Diversity in Ticks From the China–Russia–North Korea Border Region

open access: yesTransboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.
Ticks serve as critical viral vectors, and border regions, acting as convergence zones of complex ecosystems, provide diverse habitats for ticks and their hosts, thereby underscoring the need to investigate the tick‐borne virome composition in such areas. In this study, metatranscriptomic analysis of five tick species, namely Haemaphysalis longicornis,
Zhe Liu   +15 more
wiley   +1 more source

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