Results 161 to 170 of about 4,807 (202)

Ribavirin Therapy for Hantaan Virus Infection in Suckling Mice

Journal of Infectious Diseases, 1986
We recently reported that ribavirin inhibited Hantaan virus (HV) replication in vitro. In the present study, we used the HV suckling mouse model to evaluate the efficacy of treatment with various doses of ribavirin. Beginning on day 10, untreated animals, infected with ten times the amount of HV (strain 76/118) required to kill 50% of the animals, lost
J W, Huggins, G R, Kim, O M, Brand, K T, McKee   +3 more
openaire   +2 more sources

[Hantaan virus infection in Twente].

Nederlands tijdschrift voor geneeskunde, 1991
To find out if Hantavirus infection, as a cause of acute renal failure, has been overlooked in the past. To determine if Hantavirus can be found in wild rodents, particularly in red bank voles (Clethrionomys glareolus), living in the area.General hospital, Twente area.Retrospective selection of patients, hospitalised between 1970 and 1989 with renal ...
J G, Jordans, J, Groen, J, Clement, A, Lefevre, V, Haraldsdòttir, A D, Osterhaus   +5 more
openaire   +1 more source

Pathogenesis of experimental Hantaan virus infection in laboratory rats

Archives of Virology, 1986
Weanling Fischer rats inoculated intramuscularly with Hantaan virus (strain 76-118) developed subclinical infections characterized by transient viremia and shedding of virus in saliva, persistence of virus in lung, pancreas, spleen and liver, and development of fluorescent and neutralizing antibodies in serum with immune complex deposition in lung ...
P W, Lee, R, Yanagihara, C J, Gibbs, D C, Gajdusek   +3 more
openaire   +2 more sources

Development of monoclonal antibodies against Hantaan virus nucleocapsid protein

Clinical Diagnostic Laboratory Immunology, 1995
Forty-five hybridoma cell lines producing monoclonal antibodies against Hantaan virus, the etiologic agent of hemorrhagic fever with renal syndrome, were generated by fusion of P3-X63-Ag8.V653 myeloma cells with spleen cells of mice immunized with inactivated Hantaan virus vaccine.
I S, Ha, Y, Choi, Y S, Park, H I, Cheong, J W, Koo, I S, Kim, E C, Kim, S, Kim, J S, Lee   +8 more
openaire   +2 more sources

Antigenic subunits of Hantaan virus expressed by baculovirus and vaccinia virus recombinants

Journal of Virology, 1990
Baculovirus and vaccinia virus vectors were used to express the small (S) and medium (M) genome segments of Hantaan virus. Expression of the complete S or M segments yielded proteins electrophoretically indistinguishable from Hantaan virus nucleocapsid protein or envelope glycoproteins (G1 and G2), and expression of portions of the M segment, encoding ...
C S, Schmaljohn, Y K, Chu, A L, Schmaljohn, J M, Dalrymple   +3 more
openaire   +2 more sources

Hantaan Virus

Journal of the Royal Society of Health, 1984
openaire   +3 more sources

SEROEPIDEMIOLOGY OF HANTAAN VIRUS

The Lancet, 1982
C J, Gibbs, A, Takenaka, M, Franko, D C, Gajdusek, M D, Griffin, J, Chields, G W, Korch, D, Wartzok   +7 more
openaire   +2 more sources

Guanylate‐binding protein 1 inhibits Hantaan virus infection by restricting virus entry

Journal of Medical Virology
Abstract Hantaan virus (HTNV) infection can cause hemorrhagic fever with renal syndrome (HFRS) in humans, and currently, there are no long‐standing protective vaccines or specific antivirals available. Guanylate‐binding protein 1 ( GBP1 ) is an interferon‐stimulated gene ...
Tianle Gu, Sirui Qu, Junmei Zhang, Qikang Ying, Xiaoxiao Zhang, Yunhua Lv, Rongrong Liu, Yunan Feng, Fang Wang, Xingan Wu   +9 more
openaire   +2 more sources

Cervical cancer prevention and control in women living with human immunodeficiency virus

Ca-A Cancer Journal for Clinicians, 2021
Philip E Castle, Vikrant V Sahasrabuddhe
exaly  

Current treatment and recent progress in gastric cancer

Ca-A Cancer Journal for Clinicians, 2021
Smita S Joshi, Brian D Badgwell
exaly