Results 51 to 60 of about 1,663,102 (228)
Hantaan virus infection induces human mucosal-associated invariant T cell pyroptosis through IRE1α pathway. [PDF]
Zhang Y+19 more
europepmc +2 more sources
To gain further insight into the molecular epidemiology of Hantaan virus (HTNV) in Guizhou, China, rodents were captured in this region in 2004 and 2005. In addition, serum samples were collected from four patients. Ten hantaviruses were isolated successfully in cell culture from four humans, two Apodemus agrarius, three Rattus norvegicus and one ...
Yang Zou+9 more
openalex +3 more sources
A Brief History of Bunyaviral Family Hantaviridae
The discovery of Hantaan virus as an etiologic agent of hemorrhagic fever with renal syndrome in South Korea in 1978 led to identification of related pathogenic and nonpathogenic rodent-borne viruses in Asia and Europe.
Jens H. Kuhn, Connie S. Schmaljohn
doaj +1 more source
Chloroquine, an Anti-Malaria Drug as Effective Prevention for Hantavirus Infections
We investigated whether chloroquine can prevent hantavirus infection and disease in vitro and in vivo, using the Hantaan virus newborn C57BL/6 mice model and the Syrian hamster model for Andes virus.
Valentijn Vergote+5 more
doaj +1 more source
Hantaan virus is a dangerous human pathogen whose segmented negative-stranded RNA genome is replicated and transcribed by a virally-encoded multi-functional polymerase.
Quentin Durieux Trouilleton+3 more
semanticscholar +1 more source
Cell Fusion Activities of Hantaan Virus Envelope Glycoproteins [PDF]
ABSTRACT Hantaan virus (HTNV)-infected Vero E6 cells undergo cell fusion with both infected and uninfected cells under low-pH conditions. Flow cytometry and fluorescence microscopy of HTNV-infected Vero E6 cells showed that envelope glycoproteins (GPs) were located both on the cell surface and in the cytoplasm.
Michiko Ogino+6 more
openalex +4 more sources
A Case of Graves' Disease Combined with Hantaan Virus Infection
Graves' disease (GD) is generally presented by thyrotoxicosis with hyperthyroidism, and it is an organ-specific autoimmune disease induced by thyroid-stimulating hormone receptor autoantibodies. However, among diverse etiologies, viral infections have been suggested to trigger or to be involved in the pathogenesis of GD. Hantaan virus infection causing
Heung Yong Jin+5 more
openalex +4 more sources
Structural Studies of Hantaan Virus [PDF]
ABSTRACT Hantaan virus is the prototypic member of the Hantavirus genus within the family Bunyaviridae and is a causative agent of the potentially fatal hemorrhagic fever with renal syndrome.
Colleen B. Jonsson+6 more
openaire +3 more sources
BackgroundHemorrhagic fever with renal syndrome (HFRS) caused by hantaviruses is a frequently reported acute hemorrhagic fever in South Korea. These viruses are transmitted by various rodent species such as Apodemus agrarius.Methodology/principal ...
Mi Hee Seo+5 more
doaj +1 more source
Processing of genome 5' termini as a strategy of negative-strand RNA viruses to avoid RIG-I-dependent interferon induction. [PDF]
Innate immunity is critically dependent on the rapid production of interferon in response to intruding viruses. The intracellular pathogen recognition receptors RIG-I and MDA5 are essential for interferon induction by viral RNAs containing 5 ...
Matthias Habjan+11 more
doaj +1 more source