Results 51 to 60 of about 4,807 (202)
Cell Fusion Activities of Hantaan Virus Envelope Glycoproteins [PDF]
Journal of Virology, 2004 ABSTRACT Hantaan virus (HTNV)-infected Vero E6 cells undergo cell fusion with both infected and uninfected cells under low-pH conditions. Flow cytometry and fluorescence microscopy of HTNV-infected Vero E6 cells showed that envelope glycoproteins (GPs) were located both on the cell surface and in the cytoplasm.
Michiko Ogino +6 more
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Hantaan Virus Triggers TLR3-Dependent Innate Immune Responses [PDF]
The Journal of Immunology, 2009 Abstract Immediately after viral infection, innate responses including expression of IFN-α/β and IFN-stimulated genes (ISGs) are elicited ubiquitously by recruitment of specific pathogen recognition receptors. The velocity to induce IFN-α/β and ISGs in response to an infection is often decisive for virulence.
Wiebke, Handke +4 more
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mBio, 2019 Rodent-to-human transmission of hantaviruses is associated with severe disease. Currently, no FDA-approved, specific antivirals or vaccines are available, and the requirement for high biocontainment (biosafety level 3 [BSL-3]) laboratories limits ...
Megan M. Slough +2 more
doaj +1 more source
Pathogenesis of Hantaan Virus in Mice
Journal of General Virology, 1989 The virulence of two virus clones (HV cl-1 and HV cl-2) of Hantaan virus, which were plaque-purified on Vero E6 cells, were compared in suckling mice infected by the intraperitoneal or intracerebral route. HV cl-1 increased the mortality of the mice whereas HV cl-2 did not.
M, Tamura +5 more
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eLife, 2023 Hantaviruses are high-priority emerging pathogens carried by rodents and transmitted to humans by aerosolized excreta or, in rare cases, person-to-person contact.
Taylor B Engdahl +21 more
doaj +1 more source
Hantaan Virus: Identification of Virion Proteins
Journal of General Virology, 1984 SDS-PAGE and immunoprecipitation analyses were carried out on the virion and cell-associated proteins of Hantaan virus, the causative agent of haemorrhagic fever with renal syndrome (HFRS). Purified virions have a density of 1.17 g/ml in sucrose, and contain four proteins with molecular weights of 45 000 (45K), 56K, 72K and 200K, confirming recent ...
L H, Elliott, M P, Kiley, J B, McCormick
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Hemorrhagic fever with renal syndrome：pathogenesis and clinical picture
Frontiers in Cellular and Infection Microbiology, 2016 Hantaan virus (HTNV) causes hemorrhagic fever with renal syndrome (HFRS), which is a zoonosis endemic in eastern Asia, especially in China. The reservoir host of HTNV is field mouse (Apodemus agraricus).
Hong eJiang +4 more
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Acalculous cholecystitis associated with Hantaan virus: A case report. [PDF]
Ann Hepatobiliary Pancreat Surg, 2019 Acute acalculous cholecystitis (AAC) still remains one of the most elusive diagnoses and occurs in various conditions. Although AACs caused by viral infections are rare, various viruses have been revealed to cause AAC. Here we present a case in which a man suffered from AAC caused by a Hantaan virus infection.
Kim SH, Park S, Choi J.
europepmc +4 more sources
Hemorrhagic Fever with Renal Syndrome in 4 US Soldiers, South Korea, 2005
Emerging Infectious Diseases, 2009 Four US soldiers acquired hemorrhagic fever with renal syndrome while training near the Demilitarized Zone, South Korea, in 2005. Hantaan virus sequences were amplified by reverse transcription–PCR from patient serum samples and from lung tissues of ...
Jin-Won Song +10 more
doaj +1 more source
Leukemoid Reaction in Complicated Haemorrhagic Fever with Renal Syndrome [PDF]
Journal of Clinical and Diagnostic Research, 2017 Hantaan Virus (HTNV) infections are mostly associated with fever, haemorrhagic and renal manifestations, known as Haemorrhagic Fever with Renal Syndrome (HFRS). We herein describe three cases with acute HTNV infection, confirming that HTNV infection may
Xiaopeng Yang +4 more
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