Results 51 to 60 of about 1,663,102 (228)

Hantaan virus infection induces human mucosal-associated invariant T cell pyroptosis through IRE1α pathway. [PDF]

Commun Biol
Zhang Y, Liu H, Liu D, Zhang H, Ma Y, Li N, Zhang C, Xue M, Wang F, Jia X, Zhang H, Tang K, Xu X, Wang S, Wei Y, Yang X, Zuo J, Chen L, Jin B, Zhang Y.   +19 more
europepmc   +2 more sources

Molecular diversity and phylogeny of Hantaan virus in Guizhou, China: evidence for Guizhou as a radiation center of the present Hantaan virus

Journal of General Virology, 2008
To gain further insight into the molecular epidemiology of Hantaan virus (HTNV) in Guizhou, China, rodents were captured in this region in 2004 and 2005. In addition, serum samples were collected from four patients. Ten hantaviruses were isolated successfully in cell culture from four humans, two Apodemus agrarius, three Rattus norvegicus and one ...
Yang Zou, Jing Hu, Zhao-Xiao Wang, Dingming Wang, Minghui Li, Guo‐Dong Ren, Duan ZhengXiu, Zhen F. Fu, Alexander Plyusnin, Yǒng-Zhèn Zhāng   +9 more
openalex   +3 more sources

A Brief History of Bunyaviral Family Hantaviridae

Diseases, 2023
The discovery of Hantaan virus as an etiologic agent of hemorrhagic fever with renal syndrome in South Korea in 1978 led to identification of related pathogenic and nonpathogenic rodent-borne viruses in Asia and Europe.
Jens H. Kuhn, Connie S. Schmaljohn
doaj   +1 more source

Chloroquine, an Anti-Malaria Drug as Effective Prevention for Hantavirus Infections

Frontiers in Cellular and Infection Microbiology, 2021
We investigated whether chloroquine can prevent hantavirus infection and disease in vitro and in vivo, using the Hantaan virus newborn C57BL/6 mice model and the Syrian hamster model for Andes virus.
Valentijn Vergote, Lies Laenen, Raf Mols, Patrick Augustijns, Marc Van Ranst, Piet Maes   +5 more
doaj   +1 more source

Structural characterization of the oligomerization of full-length Hantaan virus polymerase into symmetric dimers and hexamers

bioRxiv, 2023
Hantaan virus is a dangerous human pathogen whose segmented negative-stranded RNA genome is replicated and transcribed by a virally-encoded multi-functional polymerase.
Quentin Durieux Trouilleton, Dominique Housset, B. Arragain, Hélène Malet   +3 more
semanticscholar   +1 more source

Cell Fusion Activities of Hantaan Virus Envelope Glycoproteins [PDF]

Journal of Virology, 2004
ABSTRACT Hantaan virus (HTNV)-infected Vero E6 cells undergo cell fusion with both infected and uninfected cells under low-pH conditions. Flow cytometry and fluorescence microscopy of HTNV-infected Vero E6 cells showed that envelope glycoproteins (GPs) were located both on the cell surface and in the cytoplasm.
Michiko Ogino, Kumiko Yoshimatsu, Hideki Ebihara, Koichi Araki, Byoung-Hee Lee, Megumi J. Okumura, Jiro Arikawa   +6 more
openalex   +4 more sources

A Case of Graves' Disease Combined with Hantaan Virus Infection

Journal of Korean Medical Science, 2009
Graves' disease (GD) is generally presented by thyrotoxicosis with hyperthyroidism, and it is an organ-specific autoimmune disease induced by thyroid-stimulating hormone receptor autoantibodies. However, among diverse etiologies, viral infections have been suggested to trigger or to be involved in the pathogenesis of GD. Hantaan virus infection causing
Heung Yong Jin, Seon Mee Kang, So Young Kim, Ji Hyun Park, Hong Sun Baek, Tae Sun Park   +5 more
openalex   +4 more sources

Structural Studies of Hantaan Virus [PDF]

Journal of Virology, 2011
ABSTRACT Hantaan virus is the prototypic member of the Hantavirus genus within the family Bunyaviridae and is a causative agent of the potentially fatal hemorrhagic fever with renal syndrome.
Colleen B. Jonsson, Colleen B. Jonsson, Anthony J. Battisti, Michael G. Rossmann, Bärbel Kaufmann, Yong-Kyu Chu, Paul R. Chipman   +6 more
openaire   +3 more sources

Emerging hantavirus infection in wild rodents captured in suburbs of Gwangju Metropolitan City, South Korea.

PLoS Neglected Tropical Diseases, 2022
BackgroundHemorrhagic fever with renal syndrome (HFRS) caused by hantaviruses is a frequently reported acute hemorrhagic fever in South Korea. These viruses are transmitted by various rodent species such as Apodemus agrarius.Methodology/principal ...
Mi Hee Seo, Choon-Mee Kim, Dong-Min Kim, Na Ra Yun, Jung Wook Park, Jae Keun Chung   +5 more
doaj   +1 more source

Processing of genome 5' termini as a strategy of negative-strand RNA viruses to avoid RIG-I-dependent interferon induction. [PDF]

PLoS ONE, 2008
Innate immunity is critically dependent on the rapid production of interferon in response to intruding viruses. The intracellular pathogen recognition receptors RIG-I and MDA5 are essential for interferon induction by viral RNAs containing 5 ...
Matthias Habjan, Ida Andersson, Jonas Klingström, Michael Schümann, Arnold Martin, Petra Zimmermann, Valentina Wagner, Andreas Pichlmair, Urs Schneider, Elke Mühlberger, Ali Mirazimi, Friedemann Weber   +11 more
doaj   +1 more source