Results 11 to 20 of about 13,318 (158)
Unraveling the Mechanistic Links Between Species Diversity and Infection Risk From Zoonotic Pathogens With Direct Transmission Among Reservoir Hosts: Rodent-Orthohantavirus Systems as Models. [PDF]
Ecol EvolIn this review, we synthesize mechanistic evidence for diversity‐disease patterns in rodent‐orthohantavirus systems in the Americas, models of directly transmitted disease systems. We found that host regulation has been examined the most while other mechanisms have received less attention. Based on our findings, we propose that for a negative diversity‐
Eleftheriou A, Luis AD.
europepmc +2 more sources
Journal of Clinical Laboratory Analysis, Volume 39, Issue 23, December 2025.Prompt access to care with proper treatment is essential for preventing patients from developing renal failure and unfavorable outcomes. This study aimed to elucidate laboratory parameters associated with HFRS severity and prognosis to predict disease course and initiate prompt clinical management.
Hong Shi +11 more
wiley +1 more source
Journal of Extracellular Vesicles, Volume 14, Issue 12, December 2025.ABSTRACT As a novel identified manner of cell death, NETosis is widely regarded as an effective approach to resist pathogen infection but mainly focused on vertebrates with systematic cell typing. Besides, the role of extracellular vesicles (EVs), which are essential tools for intercellular information exchange, in regulating NETosis during pathogen ...
Hang Hu +4 more
wiley +1 more source
Public Health Challenges, Volume 4, Issue 4, December 2025.GRAPHICAL ABSTRACT Conflict‐driven destruction in Gaza has caused water and sanitation collapse, leading to infestations of rodents and insects, escalating public health risks among displaced populations. ABSTRACT The current study investigates the severe environmental and public health impacts resulting from the ongoing conflict in the Gaza Strip ...
Zuhair Dardona, Samia Boussaa
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Advanced Science, Volume 12, Issue 42, November 13, 2025.Current herpesvirus treatments targeting the viral DNA polymerase are limited by toxicities and drug resistance. Novel compounds inhibiting the nuclease activity of the herpes simplex virus 1 (HSV‐1) terminase complex, required for viral genome packaging, have been identified.
Sabina Andreu +12 more
wiley +1 more source
Ecologic Traits Analysis for Identifying Rodent Hosts for Arenavirus and Hepacivirus in the Americas
Biotropica, Volume 57, Issue 6, November 2025.Over half of emerging human pathogens originate from wildlife, with rodents serving as key zoonotic hosts. This study used ecological trait‐based models to identify rodent traits associated with arenavirus and hepacivirus infections and detect potential host species across the Americas, our models achieve high predictive accuracy (AUC = 0.92–0.96).
María del Carmen Villalobos‐Segura +3 more
wiley +1 more source
Ecology and Evolution, Volume 15, Issue 10, October 2025.Yunnan Province, the most serious scrub typhus endemic areas in China, provides abundant ecological resources that sustain parasite and host populations. The distribution of vector‐borne diseases is driven by interactions between hosts, vectors and the environment, revealing critical ecological dynamics.
Yun‐Yan Luo +8 more
wiley +1 more source
Global Challenges, Volume 9, Issue 10, October 2025.This narrative review presents evidence from 2020 to 2025 on antiviral medications, adjunctive therapies, and nutritional interventions for COVID‐19. It highlights the roles of remdesivir, monupiravir, nirmatrelvir/ritonavir, corticosteroids, vitamins, and hygiene practices, emphasizing an integrated approach that combines pharmacologic treatments ...
Wan‐Ting Kuo, I‐Hsiu Lai
wiley +1 more source
Health Science Reports, Volume 8, Issue 10, October 2025.ABSTRACT Background and Aims Severe fever with thrombocytopenia syndrome virus (SFTSV) infection causes profound dysregulation of humoral immunity, leading to immunopathology and impaired viral clearance. However, the mechanisms underlying B cell dysfunction and inadequate antibody responses remain poorly defined.
Hongyan Hou +5 more
wiley +1 more source
Hemodialysis International, Volume 29, Issue 4, Page 647-654, October 2025.ABSTRACT Introduction Chronic kidney disease is a global public health issue, affecting approximately 10% of the world's population, and more than 3 million people living with kidney failure who are estimated to be on maintenance dialysis programs, with the majority receiving hemodialysis (HD).
I. Haddiya +5 more
wiley +1 more source