Results 1 to 10 of about 3,627,071 (246)

Structure of the Hantavirus Nucleoprotein Provides Insights into the Mechanism of RNA Encapsidation

Cell Reports, 2016
Hantaviruses are etiological agents of life-threatening hemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome. The nucleoprotein (N) of hantavirus is essential for viral transcription and replication, thus representing an ...
Daniel Olal, Oliver Daumke
doaj   +1 more source

NETosis‐Like Response Triggered by Extracellular Vesicle (EV)‐Delivered Viral Nucleic Acid, a Novel Cellular Immune Mechanism in Crustacean

Journal of Extracellular Vesicles, Volume 14, Issue 12, December 2025.
ABSTRACT As a novel identified manner of cell death, NETosis is widely regarded as an effective approach to resist pathogen infection but mainly focused on vertebrates with systematic cell typing. Besides, the role of extracellular vesicles (EVs), which are essential tools for intercellular information exchange, in regulating NETosis during pathogen ...
Hang Hu, Chunyi Zhong, Xinshan Zhao, Cheng Yi, Yi Gong   +4 more
wiley   +1 more source

Hantavirus Infection in the Republic of Georgia

Emerging Infectious Diseases, 2009
We describe a laboratory-confirmed case of hantavirus infection in the Republic of Georgia. Limited information is available about hantavirus infections in the Caucasus, although the infection has been reported throughout Europe and Russia.
Tinatin Kuchuloria, Danielle V. Clark, Matthew J. Hepburn, Tengiz Tsertsvadze, Guillermo Pimentel, Paata Imnadze   +5 more
doaj   +1 more source

Insect and Mice Infestations in Gaza Displacement Camps: A Field‐Based Study on Vector‐Borne Diseases Amid the 2023–2025 Gaza War

Public Health Challenges, Volume 4, Issue 4, December 2025.
GRAPHICAL ABSTRACT Conflict‐driven destruction in Gaza has caused water and sanitation collapse, leading to infestations of rodents and insects, escalating public health risks among displaced populations. ABSTRACT The current study investigates the severe environmental and public health impacts resulting from the ongoing conflict in the Gaza Strip ...
Zuhair Dardona, Samia Boussaa
wiley   +1 more source

NK cell activation in human hantavirus infection explained by virus-induced IL-15/IL15Rα expression. [PDF]

PLoS Pathogens, 2014
Clinical infection with hantaviruses cause two severe acute diseases, hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). These diseases are characterized by strong immune activation, increased vascular permeability, and
Monika Braun, Niklas K Björkström, Shawon Gupta, Karin Sundström, Clas Ahlm, Jonas Klingström, Hans-Gustaf Ljunggren   +6 more
doaj   +1 more source

Discovery of a Baloxavir‐Inspired Endonuclease Inhibitor That Prevents Herpes Simplex Virus 1 Replication in Cell Culture and In Vivo

Advanced Science, Volume 12, Issue 42, November 13, 2025.
Current herpesvirus treatments targeting the viral DNA polymerase are limited by toxicities and drug resistance. Novel compounds inhibiting the nuclease activity of the herpes simplex virus 1 (HSV‐1) terminase complex, required for viral genome packaging, have been identified.
Sabina Andreu, Kai Tang, Jiahui Zhou, Gabriel Pino‐Peco, Nerea López‐Carrobles, Raquel Bello‐Morales, Daniel Galdo‐Torres, Lina Zhang, Federico Gago, José Antonio López‐Guerrero, Xinyong Liu, Peng Zhan, Luis Menéndez‐Arias   +12 more
wiley   +1 more source

A five-year perspective on the situation of haemorrhagic fever with renal syndrome and status of the hantavirus reservoirs in Europe, 2005-2010 [PDF]

, 2011
Hantavirus infections are reported from many countries in Europe and with highly variable annual case numbers. In 2010, more than 2,000 human cases were reported in Germany, and numbers above the baseline have also been registered in other European ...
Aberle, S.W. (Stephan), Alves, M.J. (M. João), Avsic-Zupanc, T., Beersma, M.F.C. (Thijs), Bino, S., Ceianu, C.S., Christova, I., Connell, J. (John), Dudman, S.G. (Susanne Gjeruldsen), Engler, O., Esbroeck, M. (M.) van, Eßbauer, S., Golovljova, I., Heyman, P., Hukic, M., Klempa, B., Korukluoglu, G., Lundkvist, Å. (Åke), Nicoletti, L., Nowakowska, A., Opp, M. (Matthias), Papa, A. (Anna), Tenorio, A., Tordo, N. (Noël), Ulrich, R.G. (Rainer), Vaheri, A. (Antti), Visontai, I., Zelena, H. (Hana)   +27 more
core   +1 more source

Ecologic Traits Analysis for Identifying Rodent Hosts for Arenavirus and Hepacivirus in the Americas

Biotropica, Volume 57, Issue 6, November 2025.
Over half of emerging human pathogens originate from wildlife, with rodents serving as key zoonotic hosts. This study used ecological trait‐based models to identify rodent traits associated with arenavirus and hepacivirus infections and detect potential host species across the Americas, our models achieve high predictive accuracy (AUC = 0.92–0.96).
María del Carmen Villalobos‐Segura, Oscar Rico‐Chavéz, Gerardo Suzán, Andrea Chaves   +3 more
wiley   +1 more source

Conserved Endonuclease Function of Hantavirus L Polymerase. [PDF]

, 2016
Hantaviruses are important emerging pathogens belonging to the Bunyaviridae family. Like other segmented negative strand RNA viruses, the RNA-dependent RNA polymerase (RdRp) also known as L protein of hantaviruses lacks an intrinsic "capping activity ...
Engler, O., Johansson, M.U., Kunz, S., Rothenberger, S., Torriani, G.   +4 more
core   +2 more sources

Variation in Small Mammal Species Composition and the Occurrence of Parasitic Mites in Two Landscapes in a Scrub Typhus Endemic Region of Western Yunnan Province, China

Ecology and Evolution, Volume 15, Issue 10, October 2025.
Yunnan Province, the most serious scrub typhus endemic areas in China, provides abundant ecological resources that sustain parasite and host populations. The distribution of vector‐borne diseases is driven by interactions between hosts, vectors and the environment, revealing critical ecological dynamics.
Yun‐Yan Luo, Jia‐Xiang Yin, Zong‐Ti Shao, Zeng‐Kan Liu, Shou‐Qin Yin, Jiang‐Li Lu, Jin‐Chun Li, Rong Wei, Alan Frederick Geater   +8 more
wiley   +1 more source