Serological Evidence of Human Orthohantavirus Infections in Barbados, 2008 to 2016
Pathogens, 2021 Background: Hantavirus pulmonary syndrome (HPS) is well-known in South and North America; however, not enough data exist for the Caribbean. The first report of clinical orthohantavirus infection was obtained in Barbados, but no other evidence of clinical
Kirk Osmond Douglas +2 more
exaly +3 more sources
Hantavirus seroprevalence and associated factors for exposure in south-central Uganda [PDF]
Emerging Microbes and InfectionsOrthohantaviruses are largely rodent-borne pathogens that can cause haemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome. In Uganda, the risk of human exposure is heightened by known rodent hosts, close human-rodent interaction ...
Gerald Katushabe +14 more
doaj +2 more sources
Viruses, 2021 In 2012, Tigray orthohantavirus was discovered in Ethiopia, but its seasonal infection in small mammals, and whether it poses a risk to humans was unknown.
Yonas Meheretu +2 more
exaly +3 more sources
First Molecular Detection of Orthohantaviruses (Orthohantavirus hantanense and O. jejuense) in Trombiculid Mites from Wild Rodents in the Republic of Korea [PDF]
PathogensOrthohantaviruses are zoonotic pathogens that cause severe diseases in humans primarily through inhalation of aerosols from rodent excreta. Recent studies suggest that ectoparasites may be potential vectors for Orthohantaviruses.
Seong Yoon Kim +3 more
doaj +2 more sources
Hypopituitarism after Orthohantavirus Infection: What is Currently Known?
Viruses, 2019 Several case reports have described hypopituitarism following orthohantavirus infection, mostly following Puumala virus. The pathogenesis of this seemingly rare complication of orthohantavirus infection remains unknown.
Thomas Langerak +2 more
exaly +3 more sources
Discovery and characterization of Sager Creek virus, a new orthohantavirus in prairie voles (Microtus ochrogaster) [PDF]
npj VirusesWe report the discovery and characterization of a new orthohantavirus species in prairie voles (Microtus ochrogaster) named Sager Creek virus (SACRV).
Nathaniel Mull +6 more
doaj +2 more sources
Characterisation of Orthohantavirus Serotypes in Human Infections in Kazakhstan [PDF]
VirusesOrthohantavirus infection is a zoonotic disease transmitted to humans through contact with infected rodents. In Eurasia, Old World Orthohantaviruses can cause haemorrhagic fever with renal syndrome (HFRS), while in the Americas, New World ...
Nur Tukhanova +10 more
doaj +2 more sources
Orthohantavirus Replication in the Context of Innate Immunity
Viruses, 2023 Orthohantaviruses are rodent-borne, negative-sense RNA viruses that are capable of causing severe vascular disease in humans. Over the course of viral evolution, these viruses have tailored their replication cycles in such a way as to avoid and/or ...
Autumn T Lapointe +2 more
exaly +3 more sources
Pathogenicity and virulence of Rodent-Borne Orthohantaviruses [PDF]
VirulenceThe Orthohantavirus genus in the family Hantaviridae includes viruses that cause zoonotic diseases in humans known as hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). Exposure of humans to these viruses occurs through
Shannon L. Taylor +3 more
doaj +2 more sources
A pan-orthohantavirus human lung xenograft mouse model and its utility for preclinical studies. [PDF]
PLoS PathogensOrthohantaviruses are emerging zoonotic viruses that can infect humans via the respiratory tract. There is an unmet need for an in vivo model to study infection of different orthohantaviruses in physiologically relevant tissue and to assess the efficacy ...
Melanie Rissmann +12 more
doaj +2 more sources