Results 21 to 30 of about 7,672 (161)

Complex History of Codiversification and Host Switching of a Newfound Soricid-Borne Orthohantavirus in North America

Viruses, 2019
Orthohantaviruses are tightly linked to the ecology and evolutionary history of their mammalian hosts. We hypothesized that in regions with dramatic climate shifts throughout the Quaternary, orthohantavirus diversity and evolution are shaped by dynamic ...
Schuyler W Liphardt, Richard Yanagihara
exaly   +3 more sources

An Improved Workflow for the Quantification of Orthohantavirus Infection Using Automated Imaging and Flow Cytometry

Viruses
Determination of the infectious titer is a central requirement when working with pathogenic viruses. The plaque or focus assay is a commonly used but labor- and time-consuming approach for determining the infectious titer of orthohantavirus samples.
Christian Sieben, Laura Menke
exaly   +3 more sources

Human Orthohantavirus Infections: A Narrative Review

Pathogens
Orthohantaviruses are zoonotic pathogens belonging to the family Hantaviridae and are responsible for significant human disease. These infections are characterized by acute systemic illness, vascular dysfunction, and, in severe cases, hemorrhage and ...
Vitor Duque
doaj   +2 more sources

High Prevalence of Brucella microti, Co-Infections With Other Zoonotic Pathogens, and Public Health Risk Related to Overpopulated Common Voles (Microtus arvalis), Czech Republic. [PDF]

APMIS
ABSTRACT The common vole (Microtus arvalis) is one of the most abundant rodent species in Europe and is known for its cyclic population outbreaks, which result in significant crop damage and an increased risk of transmission of zoonotic pathogens to humans.
Strakova P, Dokulilova M, Heroldova M, Fortova A, Suchomel J, Rudolf I, Salat J.   +6 more
europepmc   +2 more sources

Orthohantavirus Pathogenesis and Cell Tropism [PDF]

Frontiers in Cellular and Infection Microbiology, 2020
Orthohantaviruses are zoonotic viruses that are naturally maintained by persistent infection in specific reservoir species. Although these viruses mainly circulate among rodents worldwide, spill-over infection to humans occurs. Orthohantavirus infection in humans can result in two distinct clinical outcomes: hemorrhagic fever with renal syndrome (HFRS)
Danny Noack, Marco Goeijenbier, Marco Goeijenbier, Chantal B. E. M. Reusken, Chantal B. E. M. Reusken, Marion P. G. Koopmans, Barry H. G. Rockx   +6 more
openaire   +6 more sources

Orthohantavirus Spp. – Review Of Genus [PDF]

Postępy Mikrobiologii - Advancements of Microbiology, 2021
Abstract The infections caused by orthohantaviruses were already known in the Middle Ages as “English sweats.” There are two main diseases caused by these viruses – HPS (hantavirus pulmonary syndrome) and HFRS (hemorrhagic fever with renal syndrome). Rodents are the main reservoir of these microorganisms, and humans usually catch them
Leis, Kamil, Kaczor, Patryk, Baska, Aleksandra, Kazik, Jakub, Kolan, Michalina, Grudlewska-Buda, Katarzyna, Wiktorczyk, Natalia, Skowron, Krzysztof   +7 more
openaire   +2 more sources

Epidemiological Investigation and Analysis of <i>Orthohantavirus hantanense</i> and <i>Orthohantavirus seoulense</i> From Wild Rodents in Liaoning Province, China. [PDF]

Transbound Emerg Dis
Background Liaoning Province possesses distinct ecological characteristics, including high forest cover and developed agriculture, which provide suitable habitats for various rodent species. Over the years, hemorrhagic fever with renal syndrome (HFRS), caused by members of the genus Orthohantavirus, such as Orthohantavirus hantanense (HTNV) and ...
Wang Y, Liu Q, Xin Q, Zhang M, Wu X, Zhao Y, Wen Y, Han Z, Li J, Wang J, Jiang Y, Han X, Jiang F, Xin H.   +13 more
europepmc   +2 more sources

Ecological and Individual-Level Factors Associated With Hantavirus Cardiopulmonary Syndrome Notifications and in-Hospital Mortality Among Hospitalized Patients in Chile, 2005-2022. [PDF]

Zoonoses Public Health
ABSTRACT Introduction Hantavirus cardiopulmonary syndrome (HCPS) is a severe zoonotic disease caused by Orthohantavirus andesense (Andes virus, ANDV), with significant public health burden in Chile. Despite decades of surveillance, knowledge gaps remain regarding the ecological drivers of notification burden and the individual‐level determinants of in ...
Diethelm-Varela B, Atero N, Sánchez-Rodríguez F, Martínez-Valdebenito C, Henríquez C, Córdova-Bührle F, Ferrés M, Mardones FO.   +7 more
europepmc   +2 more sources

Clinical and Molecular Epidemiology of Hemorrhagic Fever with Renal Syndrome Caused by Orthohantaviruses in Xiangyun County, Dali Prefecture, Yunnan Province, China

Vaccines, 2023
Hemorrhagic fever with renal syndrome (HFRS) is a zoonotic disease transmitted by several rodent species. We obtained clinical data of HFRS patients from the medical records of the People’s Hospital of Xiangyun County in Dali Prefecture from July 2019 to
Hao Huang, Meng Fu, Peiyu Han, Hongmin Yin, Zi Yang, Yichen Kong, Bo Wang, Xinglou Yang, Tilian Ren, Yunzhi Zhang   +9 more
doaj   +1 more source

Evidence of orthohantavirus and leptospira infections in small mammals in an endemic area of Gampaha district in Sri Lanka

One Health Outlook, 2022
Background Orthohantaviruses and leptospira are emerging zoonotic pathogens of high public health significance. The epidemiology of orthohantavirus infections and leptospirosis is similar and presents related clinical pictures in humans.
N. P. Sunil-Chandra, Åsa Fahlman, Shantha Waidyarathna, Jonas Näslund, M. V. M. L. Jayasundara, Lwande Olivia Wesula, Göran Bucht   +6 more
doaj   +1 more source