Presence and Persistence of Andes Virus RNA in Human Semen [PDF]
Viruses, 2023 When infecting humans, Andes orthohantavirus (ANDV) may cause a severe disease called hantavirus cardiopulmonary syndrome (HCPS). Following non-specific symptoms, the infection may progress to a syndrome of hemorrhagic fever combined with hyper-acute ...
Roland Züst +13 more
doaj +8 more sources
Human-to-Human Transmission of Andes Virus Modeled in Syrian Hamsters [PDF]
Emerging Infectious Diseases, 2023 Several occurrences of human-to-human transmission of Andes virus, an etiological agent of hantavirus cardiopulmonary syndrome, are documented. Syrian hamsters consistently model human hantavirus cardiopulmonary syndrome, yet neither transmission nor ...
Silke A. Riesle-Sbarbaro +5 more
doaj +5 more sources
Mother-to-Child Transmission of Andes Virus through Breast Milk, Chile [PDF]
Emerging Infectious Diseases, 2020 Andes virus (ANDV) is the only hantavirus transmitted between humans through close contact. We detected the genome and proteins of ANDV in breast milk cells from an infected mother in Chile who transmitted the virus to her child, suggesting ...
Marcela Ferrés +15 more
doaj +8 more sources
Person-to-Person Transmission of Andes Virus in Hantavirus Pulmonary Syndrome, Argentina, 2014 [PDF]
Emerging Infectious Diseases, 2020 Andes virus is unique among hantaviruses because it can be transmitted from person to person. This mechanism was previously supported by epidemiologic data and genetic evidence based only on partial sequences.
Daniel O. Alonso +11 more
doaj +7 more sources
Neutralizing Monoclonal Antibodies against the Gn and the Gc of the Andes Virus Glycoprotein Spike Complex Protect from Virus Challenge in a Preclinical Hamster Model [PDF]
mBio, 2020 Hantaviruses are the etiological agent of hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). The latter is associated with case fatality rates ranging from 30% to 50%.
James Duehr +10 more
doaj +5 more sources
Small interfering RNA inhibition of Andes virus replication. [PDF]
PLoS ONE, 2014 Andes virus (ANDV) is the most common causative agent of hantavirus pulmonary syndrome (HPS) in the Americas, and is the only hantavirus associated with human-to-human transmission. Case fatality rates of ANDV-induced HPS are approximately 40%. There are
Cheng-Feng Chiang +3 more
doaj +6 more sources
Serum levels of interleukin-6 are linked to the severity of the disease caused by Andes Virus [PDF]
PLoS Neglected Tropical Diseases, 2017 Andes virus (ANDV) is the etiological agent of hantavirus cardiopulmonary syndrome in Chile. In this study, we evaluated the profile of the pro-inflammatory cytokines IL-1β, IL-12p70, IL-21, TNF-α, IFN-γ, IL-10 and IL-6 in serum samples of ANDV-infected ...
Janepsy Diaz +2 more
exaly +8 more sources
The Major Cellular Sterol Regulatory Pathway Is Required for Andes Virus Infection [PDF]
PLoS Pathogens, 2014 The Bunyaviridae comprise a large family of RNA viruses with worldwide distribution and includes the pathogenic New World hantavirus, Andes virus (ANDV).
Emily A Bruce +2 more
exaly +7 more sources
Therapeutic Efficacy of Human Monoclonal Antibodies against Andes Virus Infection in Syrian Hamsters [PDF]
Emerging Infectious Diseases, 2021 Andes virus, an orthohantavirus endemic to South America, causes severe hantavirus cardiopulmonary syndrome associated with human-to-human transmission. No approved treatments or vaccines against this virus are available.
Brandi N. Williamson +5 more
doaj +3 more sources
Long-Term Single-Dose Efficacy of a Vesicular Stomatitis Virus-Based Andes Virus Vaccine in Syrian Hamsters [PDF]
Viruses, 2014 Andes virus (ANDV) is highly pathogenic in humans and is the primary etiologic agent of hantavirus cardiopulmonary syndrome (HCPS) in South America. Case-fatality rates are as high as 50% and there are no approved vaccines or specific therapies for ...
Joseph Prescott +3 more
doaj +6 more sources