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Viruses, 2023 Hantaviruses, genus Orthohantavirus, family Hantaviridae, order Bunyavirales, are negative-sense, single-stranded, tri-segmented RNA viruses that persistently infect rodents, shrews, and moles. Of these, only certain virus species harbored by rodents are
Evan P. Williams +6 more
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Host mTORC1 signaling regulates andes virus replication. [PDF]
J Virol, 2013 ABSTRACT Hantavirus pulmonary syndrome (HPS) is a severe respiratory disease characterized by pulmonary edema, with fatality rates of 35 to 45%. Disease occurs following infection with pathogenic New World hantaviruses, such as Andes virus (ANDV), which targets lung microvascular endothelial cells.
McNulty S +3 more
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Association of Single-Nucleotide Polymorphisms in IL28B, but Not TNF-α, With Severity of Disease Caused by Andes Virus. [PDF]
Clin Infect Dis, 2015 Angulo J +16 more
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Andes Virus Infection of Cynomolgus Macaques [PDF]
The Journal of Infectious Diseases, 2002 Andes virus (ANDV), a member of the genus Hantavirus, is a causative agent of hantavirus pulmonary syndrome (HPS) and is the only hantavirus known to be transmissible from person to person. HPS is found in North and South America and is often fatal.
Anita K, McElroy +3 more
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A lethal disease model for New World hantaviruses using immunosuppressed Syrian hamsters. [PDF]
PLoS Neglected Tropical Diseases, 2017 Hantavirus, the hemorrhagic causative agent of two clinical diseases, is found worldwide with variation in severity, incidence and mortality. The most lethal hantaviruses are found on the American continent where the most prevalent viruses like Andes ...
Valentijn Vergote +6 more
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Temporal Analysis of Andes Virus and Sin Nombre Virus Infections of Syrian Hamsters [PDF]
Journal of Virology, 2007 ABSTRACTAndes virus (ANDV) and Sin Nombre virus (SNV) are rodent-borne hantaviruses that cause a highly lethal hemorrhagic fever in humans known as hantavirus pulmonary syndrome (HPS). There are no vaccines or specific drugs to prevent or treat HPS, and the pathogenesis is not understood.
Victoria, Wahl-Jensen +6 more
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Development of a minigenome system for Andes virus, a New World hantavirus [PDF]
Archives of Virology, 2012 The development of reverse genetics systems for negative-stranded RNA viruses is a rapidly evolving field that has greatly advanced the study of the many different aspects of the viral life cycle. Andes virus (ANDV) is a highly pathogenic hantavirus found in South America that causes hantavirus pulmonary syndrome but to date remains poorly ...
Kyle S, Brown +2 more
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Viruses, 2019 Hantavirus cardiopulmonary syndrome (HCPS) is characterized by capillary leak, pulmonary edema (PE), and shock, which leads to death in up to 40% of patients.
René López +6 more
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Hantavirus pulmonary syndrome: encephalitis caused by virus Andes
Journal of NeuroVirology, 2011 Hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome (HPS) are rodent-borne emerging diseases caused by members of the genus Hantavirus, family Bunyaviridae. Some species of hantavirus may cause encephalitis, but this is the first report in Andes virus associated to HPS.
Talamonti, Lionel +5 more
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Human Vaccines & Immunotherapeutics, 2017 Andes hantavirus cardiopulmonary syndrome, transmitted by Oligoryzomys longicaudatus, has no approved treatment, a case fatality rate of 35%, and documented person-to-person transmission. An Andes vaccine, highly needed for prevention, is in development.
Francisca Valdivieso +6 more
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