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Oral Vaccination With Recombinant Vesicular Stomatitis Virus Expressing Sin Nombre Virus Glycoprotein Prevents Sin Nombre Virus Transmission in Deer Mice [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Sin Nombre virus (SNV) is the major cause of hantavirus cardiopulmonary syndrome (HCPS) in North America, a severe respiratory disease with a high fatality rate. SNV is carried by Peromyscus maniculatus, or deer mice, and human infection occurs following
Bryce M. Warner   +12 more
doaj   +7 more sources

Sin Nombre Virus and the Emergence of Other Hantaviruses: A Review of the Biology, Ecology, and Disease of a Zoonotic Pathogen [PDF]

open access: yesBiology, 2023
Sin Nombre virus (SNV) is an emerging virus that was first discovered in the Four Corners region of the United States in 1993. The virus causes a disease known as Hantavirus Pulmonary Syndrome (HPS), sometimes called Hantavirus Cardiopulmonary Syndrome ...
Andrew T. Jacob   +8 more
doaj   +4 more sources

Experimental Infection of Peromyscus Species Rodents with Sin Nombre Virus [PDF]

open access: yesEmerging Infectious Diseases, 2022
We demonstrate that 6 distinct Peromyscus rodent species are permissive to experimental infection with Sin Nombre orthohantavirus (SNV). Viral RNA and SNV antibodies were detected in members of all 6 species. P.
Kaye Quizon   +9 more
doaj   +4 more sources

Sin Nombre Virus as Unlikely Reverse Zoonotic Threat [PDF]

open access: yesEmerging Infectious Diseases
We inoculated clinical materials into deer mice to attempt isolation of Sin Nombre virus. We did not observe productive infection in the natural rodent reservoir.
Jérémie Prévost   +4 more
doaj   +4 more sources

Sin Nombre Virus Infection in Field Workers, Colorado, USA [PDF]

open access: yesEmerging Infectious Diseases, 2010
We report 2 cases of Sin Nombre virus (SNV) infection in field workers, possibly contracted through rodent bites. Screening for antibodies to SNV in rodents trapped in 2 seasons showed that 9.77% were seropositive.
Fernando Torres-Pérez   +6 more
doaj   +4 more sources

Aerostability of Sin Nombre Virus Aerosol Related to Near-Field Transmission [PDF]

open access: yesPathogens
Sin Nombre virus (SNV) is the main causative agent of hantavirus cardiopulmonary syndrome (HCPS) in North America. SNV is transmitted via environmental biological aerosols (bioaerosols) produced by infected deer mice (Peromyscus maniculatus).
Elizabeth A. Klug   +9 more
doaj   +4 more sources

Development and Characterization of a Sin Nombre Virus Transmission Model in Peromyscus maniculatus [PDF]

open access: yesViruses, 2019
In North America, Sin Nombre virus (SNV) is the main cause of hantavirus cardiopulmonary syndrome (HCPS), a severe respiratory disease with a fatality rate of 35⁻40%. SNV is a zoonotic pathogen carried by deer mice (Peromyscus maniculatus), and few
Bryce M. Warner   +9 more
doaj   +5 more sources

Increased Host Species Diversity and Decreased Prevalence of Sin Nombre Virus [PDF]

open access: yesEmerging Infectious Diseases, 2009
Emerging outbreaks of zoonotic diseases are affecting humans at an alarming rate. Until the ecological factors associated with zoonoses are better understood, disease emergence will continue. For Lyme disease, disease suppression has been demonstrated by
Laurie J. Dizney, Luis A. Ruedas
doaj   +4 more sources

Novel Focus of Sin Nombre Virus in Peromyscus eremicus Mice, Death Valley National Park, California, USA [PDF]

open access: yesEmerging Infectious Diseases, 2018
The deer mouse (Peromyscus maniculatus) is the primary reservoir for Sin Nombre virus (SNV) in the western United States. Rodent surveillance for hantavirus in Death Valley National Park, California, USA, revealed cactus mice (P.
Joseph E. Burns   +8 more
doaj   +2 more sources

Elevated Cytokines, Thrombin and PAI-1 in Severe HCPS Patients Due to Sin Nombre Virus [PDF]

open access: yesViruses, 2015
Sin Nombre Hantavirus (SNV, Bunyaviridae Hantavirus) is a Category A pathogen that causes Hantavirus Cardiopulmonary Syndrome (HCPS) with case fatality ratios generally ranging from 30% to 50%.
Virginie Bondu   +6 more
doaj   +2 more sources

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