Results 21 to 30 of about 121,983 (190)

Sin Nombre Virus in Deer Mice Captured Inside Homes, Southwestern Montana [PDF]

Emerging Infectious Diseases, 2000
From 1996 through 1999, 35 deer mice (Peromyscus maniculatus) were captured in 25 urban and suburban homes in southwestern Montana. Mice were captured throughout the year except for January; seven mice (20%) from seven (28%) of the homes were ...
Amy J. Kuenzi, Richard J. Douglass, Clifford W. Bond   +2 more
doaj   +3 more sources

Structural and functional characterization of the Sin Nombre virus L protein. [PDF]

PLoS Pathog, 2023
The Bunyavirales order is a large and diverse group of segmented negative-strand RNA viruses. Several virus families within this order contain important human pathogens, including Sin Nombre virus (SNV) of the Hantaviridae. Despite the high epidemic potential of bunyaviruses, specific medical countermeasures such as vaccines or antivirals are missing ...
Meier K, Thorkelsson SR, Durieux Trouilleton Q, Vogel D, Yu D, Kosinski J, Cusack S, Malet H, Grünewald K, Quemin ERJ, Rosenthal M.   +10 more
europepmc   +7 more sources

Tracing Transmission of Sin Nombre Virus and Discovery of Infection in Multiple Rodent Species. [PDF]

J Virol, 2021
Orthohantaviruses cause severe disease in humans and can be lethal in up to 40% of cases. Sin Nombre orthohantavirus (SNV) is the main cause of hantavirus disease in North America.
Goodfellow SM, Nofchissey RA, Schwalm KC, Cook JA, Dunnum JL, Guo Y, Ye C, Mertz GJ, Chandran K, Harkins M, Domman DB, Dinwiddie DL, Bradfute SB.   +12 more
europepmc   +4 more sources

Experimental parasite community perturbation reveals associations between Sin Nombre virus and gastrointestinal nematodes in a rodent reservoir host [PDF]

Biology Letters, 2020
Amy R Sweeny, Andrea L Graham, Amy B Pedersen   +2 more
exaly   +2 more sources

Human exposure to particulate matter potentially contaminated with sin nombre virus. [PDF]

Ecohealth, 2013
The most common mechanism for human exposure to hantaviruses throughout North America is inhalation of virally contaminated particulates. However, risk factors associated with exposure to particulates potentially contaminated with hantaviruses are generally not well understood. In North America, Sin Nombre virus (SNV) is the most common hantavirus that
Richardson KS, Kuenzi A, Douglass RJ, Hart J, Carver S.   +4 more
europepmc   +4 more sources

Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies

eLife, 2023
Hantaviruses are high-priority emerging pathogens carried by rodents and transmitted to humans by aerosolized excreta or, in rare cases, person-to-person contact.
Taylor B Engdahl, Elad Binshtein, Rebecca L Brocato, Natalia A Kuzmina, Lucia M Principe, Steven A Kwilas, Robert K Kim, Nathaniel S Chapman, Monique S Porter, Pablo Guardado-Calvo, Félix A Rey, Laura S Handal, Summer M Diaz, Irene A Zagol-Ikapitte, Minh H Tran, W Hayes McDonald, Jens Meiler, Joseph X Reidy, Andrew Trivette, Alexander Bukreyev, Jay W Hooper, James E Crowe   +21 more
doaj   +1 more source

Kinetics of immune responses in deer mice experimentally infected with Sin Nombre virus. [PDF]

J Virol, 2012
ABSTRACTDeer mice are the principal reservoir hosts of Sin Nombre virus, the etiologic agent of most hantavirus cardiopulmonary syndrome cases in North America. Infection of deer mice results in persistence without conspicuous pathology, and most, if not all, infected mice remain infected for life, with periods of viral shedding.
Schountz T, Acuña-Retamar M, Feinstein S, Prescott J, Torres-Perez F, Podell B, Peters S, Ye C, Black WC, Hjelle B.   +9 more
europepmc   +5 more sources

Neutralizing Monoclonal Antibodies against the Gn and the Gc of the Andes Virus Glycoprotein Spike Complex Protect from Virus Challenge in a Preclinical Hamster Model

mBio, 2020
Hantaviruses are the etiological agent of hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). The latter is associated with case fatality rates ranging from 30% to 50%.
James Duehr, Meagan McMahon, Brandi Williamson, Fatima Amanat, Alan Durbin, David W. Hawman, Danny Noack, Skyler Uhl, Gene S. Tan, Heinz Feldmann, Florian Krammer   +10 more
doaj   +1 more source

Broad and potently neutralizing monoclonal antibodies isolated from human survivors of New World hantavirus infection

Cell Reports, 2021
Summary: New World hantaviruses (NWHs) are endemic in North and South America and cause hantavirus cardiopulmonary syndrome (HCPS), with a case fatality rate of up to 40%. Knowledge of the natural humoral immune response to NWH infection is limited. Here,
Taylor B. Engdahl, Natalia A. Kuzmina, Adam J. Ronk, Chad E. Mire, Matthew A. Hyde, Nurgun Kose, Matthew D. Josleyn, Rachel E. Sutton, Apoorva Mehta, Rachael M. Wolters, Nicole M. Lloyd, Francisca R. Valdivieso, Thomas G. Ksiazek, Jay W. Hooper, Alexander Bukreyev, James E. Crowe, Jr.   +15 more
doaj   +1 more source

Sin Nombre Virus Pathogenesis in Peromyscus maniculatus [PDF]

Journal of Virology, 1999
ABSTRACT Sin Nombre virus (SNV), a member of the Hantavirus genus, causes acute viral pneumonia in humans and is thought to persistently infect mice. The deer mouse, Peromyscus maniculatus , has been identified as the primary reservoir host for SNV. To understand SNV infection of
D, Netski, B H, Thran, S C, St Jeor
openaire   +2 more sources