Results 21 to 30 of about 2,483 (141)

Evaluating Neutralizing Antibodies in Hantavirus-Infected Patients Using Authentic Virus and Recombinant Vesicular Stomatitis Virus Systems [PDF]

Viruses
Hantaviruses, including the Sin Nombre virus (SNV) and Andes virus (ANDV), are associated with severe global health risks, causing high mortality rates in hantavirus pulmonary syndrome (HPS) patients.
Punya Shrivastava-Ranjan, Jamie A. Kelly, Laura K. McMullan, Deborah Cannon, Laura Morgan, Payel Chatterjee, Shilpi Jain, Joel M. Montgomery, Mike Flint, César G. Albariño, Christina F. Spiropoulou   +10 more
doaj   +2 more sources

Structural and functional characterization of the Sin Nombre virus L protein. [PDF]

PLoS Pathog, 2023
The Bunyavirales order is a large and diverse group of segmented negative-strand RNA viruses. Several virus families within this order contain important human pathogens, including Sin Nombre virus (SNV) of the Hantaviridae. Despite the high epidemic potential of bunyaviruses, specific medical countermeasures such as vaccines or antivirals are missing ...
Meier K, Thorkelsson SR, Durieux Trouilleton Q, Vogel D, Yu D, Kosinski J, Cusack S, Malet H, Grünewald K, Quemin ERJ, Rosenthal M.   +10 more
europepmc   +7 more sources

Removing Deer Mice from Buildings and the Risk for Human Exposure to Sin Nombre Virus

Emerging Infectious Diseases, 2003
Trapping and removing deer mice from ranch buildings resulted in an increased number of mice, including Sin Nombre virus antibody–positive mice, entering ranch buildings.
Richard J. Douglass, Amy J. Kuenzi, Courtney Y. Williams, Samuel J. Douglass, James N. Mills   +4 more
doaj   +3 more sources

Sin Nombre Virus in Deer Mice Captured Inside Homes, Southwestern Montana [PDF]

Emerging Infectious Diseases, 2000
From 1996 through 1999, 35 deer mice (Peromyscus maniculatus) were captured in 25 urban and suburban homes in southwestern Montana. Mice were captured throughout the year except for January; seven mice (20%) from seven (28%) of the homes were ...
Amy J. Kuenzi, Richard J. Douglass, Clifford W. Bond   +2 more
doaj   +3 more sources

Community Assembly Reveals How Environmental Controls Over Rodent Competition Drive Deer Mouse Density and Hantavirus Infection [PDF]

Ecol Lett
We examined how community assembly processes shape Sin Nombre hantavirus (SNV) dynamics in rodent communities across the southwestern United States. Environmental factors structured community composition, which regulated deer mouse abundance and SNV infection, rather than diversity alone.
Luis A, Pearson D.
europepmc   +2 more sources

Experimental parasite community perturbation reveals associations between Sin Nombre virus and gastrointestinal nematodes in a rodent reservoir host [PDF]

Biology Letters, 2020
Amy B Pedersen, Andrea L Graham, Courtney Thomason   +2 more
exaly   +2 more sources

Tracing Transmission of Sin Nombre Virus and Discovery of Infection in Multiple Rodent Species. [PDF]

J Virol, 2021
Orthohantaviruses cause severe disease in humans and can be lethal in up to 40% of cases. Sin Nombre orthohantavirus (SNV) is the main cause of hantavirus disease in North America.
Goodfellow SM, Nofchissey RA, Schwalm KC, Cook JA, Dunnum JL, Guo Y, Ye C, Mertz GJ, Chandran K, Harkins M, Domman DB, Dinwiddie DL, Bradfute SB.   +12 more
europepmc   +4 more sources

Antigenic mapping and functional characterization of human New World hantavirus neutralizing antibodies

eLife, 2023
Hantaviruses are high-priority emerging pathogens carried by rodents and transmitted to humans by aerosolized excreta or, in rare cases, person-to-person contact.
Taylor B Engdahl, Elad Binshtein, Rebecca L Brocato, Natalia A Kuzmina, Lucia M Principe, Steven A Kwilas, Robert K Kim, Nathaniel S Chapman, Monique S Porter, Pablo Guardado-Calvo, Félix A Rey, Laura S Handal, Summer M Diaz, Irene A Zagol-Ikapitte, Minh H Tran, W Hayes McDonald, Jens Meiler, Joseph X Reidy, Andrew Trivette, Alexander Bukreyev, Jay W Hooper, James E Crowe   +21 more
doaj   +1 more source

Neutralizing Monoclonal Antibodies against the Gn and the Gc of the Andes Virus Glycoprotein Spike Complex Protect from Virus Challenge in a Preclinical Hamster Model

mBio, 2020
Hantaviruses are the etiological agent of hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). The latter is associated with case fatality rates ranging from 30% to 50%.
James Duehr, Meagan McMahon, Brandi Williamson, Fatima Amanat, Alan Durbin, David W. Hawman, Danny Noack, Skyler Uhl, Gene S. Tan, Heinz Feldmann, Florian Krammer   +10 more
doaj   +1 more source

Kinetics of immune responses in deer mice experimentally infected with Sin Nombre virus. [PDF]

J Virol, 2012
ABSTRACTDeer mice are the principal reservoir hosts of Sin Nombre virus, the etiologic agent of most hantavirus cardiopulmonary syndrome cases in North America. Infection of deer mice results in persistence without conspicuous pathology, and most, if not all, infected mice remain infected for life, with periods of viral shedding.
Schountz T, Acuña-Retamar M, Feinstein S, Prescott J, Torres-Perez F, Podell B, Peters S, Ye C, Black WC, Hjelle B.   +9 more
europepmc   +5 more sources